Heartleaf Houttuynia Cordata Hyaluron Soothing Clear Pad
Tracked ingredients
Key actives from our research database. Click any to read the full evidence dossier.
Evidence behind the ingredients
Real citations from our research database — one per tracked active in this product. Click any ingredient name to read its full evidence dossier.
A calming K-beauty botanical that's also antibacterial, so it pairs well for acne-prone, sensitive skin.
Huang R et al., Houttuynia cordata polysaccharides ameliorate atopic dermatitis in mice through modulation of skin immune barrier and lipid metabolism, International Journal of Biological Macromolecules 2025;314:144264 — South-Central Minzu U Wuhan; HCP restored lipid metabolic homeostasis and modulated inflammation in AD mice
Kwon N et al., Protective Effects of Fermented Houttuynia cordata Against UVA and H2O2-Induced Oxidative Stress in Human Skin Keratinocytes, Applied Biochemistry and Biotechnology 2023;195(5):3027-3046 — Korean-authored; fermented H. cordata showed antioxidant and anti-inflammatory protection against UVA/H2O2 stress
Wu Z et al., Houttuynia cordata Thunb: An Ethnopharmacological Review, Frontiers in Pharmacology 2021;12:714694 — anti-inflammatory, antibacterial, antiviral effects supporting topical applications
A pure hydrator that holds water in your skin. Makes skin look plumper and smoother almost immediately.
Bravo B et al., Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence, Dermatology and Therapy 2022;12(12):2657-2680 — HA-based cosmeceuticals reliably improve hydration and signs of skin aging
An JH et al., Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin, Annals of Dermatology 2019;31(3):263-271 — cross-linked HA microneedle patches improved wrinkles on Korean skin with minimal discomfort
Jegasothy SM et al., Efficacy of a New Topical Nano-hyaluronic Acid in Humans, Journal of Clinical and Aesthetic Dermatology 2014;7(3):27-29 — nano-HA produced up to 40% wrinkle-depth reduction, 96% hydration increase, and 55% elasticity improvement over 8 weeks
Also called "cica," it calms redness, repairs the skin barrier, and speeds up healing. The go-to for irritated or reactive skin.
Su Z et al., The Effectiveness and Safety of a Skin Care Product With Centella asiatica Leaf Extract, Ceramide NP, and Panthenol in Subjects With Sensitive Skin: A Prospective, Observational Study, Journal of Cosmetic Dermatology 2025;24(7):e70324 — Sun Yat-Sen U 4-week study; cream provided rapid relief of facial redness and supported barrier function
Cho SY et al., Comparative analysis of bioactive compounds and the anti-inflammatory and wound-healing properties of Centella asiatica, Journal of Applied Biological Chemistry 2025;68:30 — Jeju-grown C. asiatica matched/exceeded imported sources for asiaticoside content; in RAW264.7 + HaCaT models inhibited iNOS/COX-2/IL-1β/IL-6 and accelerated HaCaT wound closure
Wang L et al., A two-center randomized controlled trial of a repairing mask as an adjunctive treatment for mild to moderate rosacea, Journal of Cosmetic Dermatology 2024;23(10):3281-3286 — Centella asiatica repairing mask adjunct to minocycline improved IGA, repaired barrier, reduced rosacea symptoms (n=64)
+−4 more ingredients
Pro-vitamin B5. Deeply hydrates and helps repair the skin barrier, calming dry or compromised skin.
Gao Y et al., Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment, Journal of Cosmetic Dermatology 2025;24(7):e70223 — double-blind RCT (n=60): panthenol mask decreased erythema, enhanced hydration, repaired barrier vs saline
Cho YS et al., Use of Dexpanthenol for Atopic Dermatitis-Benefits and Recommendations Based on Current Evidence, Journal of Clinical Medicine 2022;11(14):3943 — Korean-authored review; dexpanthenol improves barrier and reduces severity in mild-to-moderate AD
Heise R et al., Accelerated wound healing with a dexpanthenol-containing ointment after fractional ablative CO2 laser resurfacing of photo-damaged skin in a randomized prospective clinical trial, Cutaneous and Ocular Toxicology 2019;38(3):274-278 — RCT: dexpanthenol significantly faster wound closure vs petroleum jelly post-laser
A gentle smoother and skin-soother. Reduces flakiness and helps the surface look more even.
Xu Z et al., Efficacy and Safety of Topical Compound Heparin Sodium Allantoin Gel for the Treatment of Rosacea, Journal of Cosmetic Dermatology 2025;24(4):e70129 — RCT (n=82, 12 weeks): allantoin gel improved erythema and alleviated itching/burning vs traditional therapy
Tan C et al., The combination of allantoin, bisabolol, D-panthenol and dipotassium glycyrrhizinate mitigates UVB-induced PGE2 synthesis by keratinocytes, International Journal of Cosmetic Science 2024;46(5):691-701 — in vitro: allantoin combination reduced UVB-induced PGE2, IL-1α, IL-6, IL-8, TNFα
Saucedo-Acuna RA et al. (Mexico), Characterization and In Vivo Assay of Allantoin-Enriched Pectin Hydrogel for the Treatment of Skin Wounds, International Journal of Molecular Sciences 2023;24(8):7377 — allantoin-pectin hydrogel reduced wound healing time by ~71% with complete closure at day 15 in rat model
A heavy-duty hydrator that also reduces irritation. Often called "better than hyaluronic acid" for sensitive skin.
Feng X et al., Exploring the Properties and Application Potential of beta-Glucan in Skin Care, Food Science and Nutrition 2025;13(4):e70212 — review concludes beta-glucan exhibits antioxidant, anti-inflammatory, barrier repair, and moisturizing bioactivities
Kussie HC et al., Avenanthramide and beta-Glucan Therapeutics Accelerate Wound Healing Via Distinct and Nonoverlapping Mechanisms, Advances in Wound Care 2024;13(4):155-166 — in vivo: beta-glucan accelerated wound closure with increased angiogenesis
Du B et al., Oat β-glucan ameliorates epidermal barrier disruption by upregulating CaSR via dectin-1-mediated ERK/p38 signaling, International Journal of Biological Macromolecules 2021 — mechanism for barrier-repair effects; in-vitro and animal-model evidence
A workhorse hydrator that pulls water into your skin. In nearly every good moisturizer for a reason.
Danby SG et al., Different types of emollient cream exhibit diverse physiological effects on the skin barrier in adults with atopic dermatitis, Clinical and Experimental Dermatology 2022;47(6):1154-1164 — glycerol+urea emollient delivered superior barrier-strengthening and irritant protection
Evans NJ et al., Human axillary skin condition is improved following incorporation of glycerol into the stratum corneum from an antiperspirant formulation, Archives of Dermatological Research 2017;309(9):739-748 — 4% glycerol penetrated axillary SC, reduced irritation, improved hydration
Fluhr JW et al., Glycerol and the skin: holistic approach to its origin and functions, British Journal of Dermatology 2008;159(1):23-34 — improves xerosis and barrier function
Sources: PubMed · KCI · J-Stage · CNKI · Wanfang · SFD · MFDS · Cochrane · SCCS · CIR. Every entry points to a specific document. See methodology for what each outcome label means.
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