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Ingredients Anti-inflammatory Centella Asiatica
24Ct
Sourced from herb
Tier · Moderate evidence
Anti-inflammatory · Barrier repair

Centella Asiatica

INCI: Centella Asiatica Extract · Also called: Cica, Gotu Kola, Tiger Grass

Also called "cica," it calms redness, repairs the skin barrier, and speeds up recovery. The go-to for irritated or reactive skin.

For your skin

Also called "cica," it calms redness, repairs the skin barrier, and speeds up recovery. The go-to for irritated or reactive skin.

Want the science? Keep reading ↓

Mechanism of action

Triterpene-rich botanical that promotes fibroblast collagen synthesis and angiogenesis in wounded skin.

Why we tier this moderate

6 cited papers across 2 countries. The mechanism is well-described and there's at least one controlled trial in the literature, but we tier this Moderate rather than Strong to stay honest about how many specific papers we cite directly.

5
International
1
Korea

Layering matrix

Compare with

Cited research

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Hur N et al., A Randomized, Double-Blind, Placebo-Controlled Trial Assessing the Effects of Oral Centella asiatica Extract on Skin Aging-Related Parameters in Middle-Aged Korean Women, Nutrients 2026

2026Positive (efficacy)PMID:42196964View source ↗
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Borowicz KK et al., Geroprotective Potential of Centella asiatica: Modulation of Cellular Aging, Nutrients 2026

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Witkowska K et al., Topical Application of Centella asiatica in Wound Healing: Recent Insights into Mechanisms and Clinical Efficacy, Pharmaceutics 2024;16(10):1252 — modern hydrogel and nanostructured Centella delivery systems accelerate wound healing across wound types

2024Meta-analysis (positive)PMID:39458583View source ↗
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Park KS, Pharmacological Effects of Centella asiatica on Skin Diseases: Evidence and Possible Mechanisms, Evidence-Based Complementary and Alternative Medicine 2021;2021:5462633 — Centella triterpenes show therapeutic effects across acne, burns, atopic dermatitis and wounds via multiple signaling pathways

2021Meta-analysis (positive)PMID:34845411View source ↗
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Jenwitheesuk K et al., A prospective randomized, controlled, double-blind trial of the efficacy using Centella cream for scar improvement, Evidence-Based Complementary and Alternative Medicine 2018;2018:9525624 — 7% Centella cream produced statistically significant pigmentation-score improvements over 12 weeks on STSG donor sites

2018Positive (efficacy)PMID:30310413View source ↗
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Bylka W et al., Centella asiatica in dermatology: an overview, Phytotherapy Research 2014;28(8):1117-1124 — pentacyclic triterpenes in Centella enhance wound healing, scar reduction, and burn recovery

Sources: 10 clinical journals and regulatory databases across the US, EU, Korea, Japan, and China. Every entry points to a specific document. See methodology for the full list and what each outcome label means.