Ingredients Anti-inflammatory Centella Asiatica
24Ct
Sourced from herb
Tier · Moderate evidence
Anti-inflammatory · Barrier repair

Centella Asiatica

INCI: Centella Asiatica Extract · Also called: Cica, Gotu Kola, Tiger Grass

Also called "cica," it calms redness, repairs the skin barrier, and speeds up healing. The go-to for irritated or reactive skin.

For your skin

Also called "cica," it calms redness, repairs the skin barrier, and speeds up healing. The go-to for irritated or reactive skin.

Want the science? Keep reading ↓

Mechanism of action

Triterpene-rich botanical that promotes fibroblast collagen synthesis and angiogenesis in wounded skin.

Why we tier this moderate

8 cited papers across 3 countries. The mechanism is well-described and there's at least one controlled trial in the literature, but we tier this Moderate rather than Strong to stay honest about how many specific papers we cite directly.

3
Korea
3
International
2
China

Layering matrix

Compare with

Cited research

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Su Z et al., The Effectiveness and Safety of a Skin Care Product With Centella asiatica Leaf Extract, Ceramide NP, and Panthenol in Subjects With Sensitive Skin: A Prospective, Observational Study, Journal of Cosmetic Dermatology 2025;24(7):e70324 — Sun Yat-Sen U 4-week study; cream provided rapid relief of facial redness and supported barrier function

2025Positive — efficacyPMID:40682399View source ↗
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Cho SY et al., Comparative analysis of bioactive compounds and the anti-inflammatory and wound-healing properties of Centella asiatica, Journal of Applied Biological Chemistry 2025;68:30 — Jeju-grown C. asiatica matched/exceeded imported sources for asiaticoside content; in RAW264.7 + HaCaT models inhibited iNOS/COX-2/IL-1β/IL-6 and accelerated HaCaT wound closure

2025Mechanism onlyKCI:ART003203648View source ↗
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Wang L et al., A two-center randomized controlled trial of a repairing mask as an adjunctive treatment for mild to moderate rosacea, Journal of Cosmetic Dermatology 2024;23(10):3281-3286 — Centella asiatica repairing mask adjunct to minocycline improved IGA, repaired barrier, reduced rosacea symptoms (n=64)

2024Positive — efficacyPMID:38831627View source ↗
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Witkowska K et al., Topical Application of Centella asiatica in Wound Healing: Recent Insights into Mechanisms and Clinical Efficacy, Pharmaceutics 2024;16(10):1252 — modern hydrogel and nanostructured Centella delivery systems accelerate wound healing across wound types

2024Meta-analysis — positivePMID:39458583View source ↗
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Park KS, Pharmacological Effects of Centella asiatica on Skin Diseases: Evidence and Possible Mechanisms, Evidence-Based Complementary and Alternative Medicine 2021;2021:5462633 — Centella triterpenes show therapeutic effects across acne, burns, atopic dermatitis and wounds via multiple signaling pathways

2021Meta-analysis — positivePMID:34845411View source ↗
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MFDS Notified Functional Cosmetic Active — Centella Asiatica Extract (skin barrier strengthening). Korean Ministry of Food and Drug Safety — notified active under the Functional Cosmetics Codex barrier-strengthening category; the standardized triterpene fraction (TECA: madecassoside, asiaticoside, asiatic acid, madecassic acid) is the documented active complex

2020Regulatory approvalMFDS:CentellaAsiatica-BarrierStrengtheningView source ↗
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Jenwitheesuk K et al., A prospective randomized, controlled, double-blind trial of the efficacy using Centella cream for scar improvement, Evidence-Based Complementary and Alternative Medicine 2018;2018:9525624 — 7% Centella cream produced statistically significant pigmentation-score improvements over 12 weeks on STSG donor sites

2018Positive — efficacyPMID:30310413View source ↗
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Bylka W et al., Centella asiatica in dermatology: an overview, Phytotherapy Research 2014;28(8):1117-1124 — pentacyclic triterpenes in Centella enhance wound healing, scar reduction, and burn recovery

2014Mechanism onlyPMID:24399761View source ↗

Sources: PubMed · KCI · J-Stage · CNKI · Wanfang · SFD · MFDS · Cochrane · SCCS · CIR. Every entry points to a specific document. See methodology for what each outcome label means.