For your skin
A heavy-duty hydrator that also reduces irritation. Often called "better than hyaluronic acid" for sensitive skin.
Want the science? Keep reading ↓Mechanism of action
Polysaccharide film-former that hydrates while modulating cutaneous immune response.
Why we tier this moderate
5 cited papers across 3 countries. The mechanism is well-described and there's at least one controlled trial in the literature, but we tier this Moderate rather than Strong to stay honest about how many specific papers we cite directly.
Layering matrix
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Cited research
Feng X et al., Exploring the Properties and Application Potential of beta-Glucan in Skin Care, Food Science and Nutrition 2025;13(4):e70212 — review concludes beta-glucan exhibits antioxidant, anti-inflammatory, barrier repair, and moisturizing bioactivities
Kussie HC et al., Avenanthramide and beta-Glucan Therapeutics Accelerate Wound Healing Via Distinct and Nonoverlapping Mechanisms, Advances in Wound Care 2024;13(4):155-166 — in vivo: beta-glucan accelerated wound closure with increased angiogenesis
Cao Y et al., Improving the outcome of treating striae gravidarum by combined therapies using topical β-glucan and 1565-nm non-ablative fractional laser, Journal of Dermatology 2022;49(9):829-836 — RCT; topical beta-glucan twice daily for 12 weeks on stretch marks
Du B et al., Oat β-glucan ameliorates epidermal barrier disruption by upregulating CaSR via dectin-1-mediated ERK/p38 signaling, International Journal of Biological Macromolecules 2021 — mechanism for barrier-repair effects; in-vitro and animal-model evidence
Jesenak M et al., β-Glucan-based cream (containing pleuran isolated from Pleurotus ostreatus) in supportive treatment of mild-to-moderate atopic dermatitis, Journal of Dermatological Treatment 2016;27(4):351-354 — split-body trial; topical beta-glucan cream improved EASI score
Sources: 10 clinical journals and regulatory databases across the US, EU, Korea, Japan, and China. Every entry points to a specific document. See methodology for the full list and what each outcome label means.