Kateceuticals Resurfacing Overnight Peel
What it's good for
Key actives from our research database. Click any to read the full evidence dossier.
A Korean-approved anti-wrinkle ingredient that encourages collagen production for a smoother, firmer look.
Good for: Anti-aging
Refills the natural barrier between your skin cells. Locks moisture in, keeps irritants out, calms dry or damaged skin.
Good for: Barrier repair
A silicone that sits on your skin as an invisible, non-greasy shield. Reduces water loss, protects against irritants (think soap, friction, incontinence), and is FDA-recognised as a skin protectant from 1-30%. The reason your favourite primer feels silky and your barrier cream actually works under makeup.
Good for: Barrier repair, Hydrating
A workhorse hydrator that pulls water into your skin. In nearly every good moisturizer for a reason.
Good for: Hydrating
Exfoliates the surface of your skin to smooth rough texture and fade dullness. The strongest of the AHAs, so start slow.
Good for: Exfoliating
A pure hydrator that holds water in your skin. Makes skin look plumper and smoother almost immediately.
Good for: Hydrating
A gentle Asian-skincare brightener derived from licorice root. Fades dark spots and calms redness, and it's a pregnancy-safe alternative to stronger fade ingredients.
Good for: Brightening, Anti-inflammatory
A multitasker that calms redness, evens out skin tone, and helps oily skin balance out. One of the safest do-a-little-of-everything ingredients.
Good for: Brightening, Barrier repair, Anti-inflammatory
Speeds up how fast your skin renews itself so old, dull cells shed faster and fresher skin shows through. Builds collagen over time, smoothing fine lines.
Good for: Anti-aging
Evidence behind the ingredients
Real citations from our research database, one per tracked active in this product. Click any ingredient name to read its full evidence dossier.
A Korean-approved anti-wrinkle ingredient that encourages collagen production for a smoother, firmer look.
Yang HJ et al., Two-phase delivery using a horse oil and adenosine-loaded dissolving microneedle patch for skin barrier restoration, moisturization, and wrinkle improvement, Journal of Cosmetic Dermatology 2019;18(3):936-943 — Korean clinical study (n=20): adenosine microneedle patches improved elasticity, hydration, dermal density, wrinkles
Kang G et al., Adenosine-loaded dissolving microneedle patches to improve skin wrinkles, dermal density, elasticity and hydration, International Journal of Cosmetic Science 2018;40(2):199-206 — Korean-authored; adenosine microneedle patches matched or exceeded adenosine cream for multiple endpoints
Kim MY et al., Effect of adenosine on melanogenesis in B16 cells and zebrafish, Annals of Dermatology 2014;26(2):209-13 — adenosine suppresses pigmentation via negative regulation of tyrosinase in cellular and zebrafish models
Refills the natural barrier between your skin cells. Locks moisture in, keeps irritants out, calms dry or damaged skin.
Andrew PV et al., Topical supplementation with physiological lipids rebalances the stratum corneum ceramide profile and strengthens skin barrier function in adults predisposed to atopic dermatitis, British Journal of Dermatology 2025;193(4):729-740 — physiological-lipid emulsion raised SC ceramide NP/AP and improved barrier function vs control
Nugroho WT, Sawitri, Astindari, Utomo B, Listiawan MY, Ervianti E, Astari L. The Efficacy of Moisturisers Containing Ceramide Compared with Other Moisturisers in the Management of Atopic Dermatitis: A Systematic Literature Review and Meta-Analysis. Indian J Dermatol. 2023;68(1):53-58. — Meta-analysis of 5 studies found ceramide-containing moisturisers produced significantly greater improvement in SCORAD compared with non-ceramide moisturisers in atopic dermatitis.
Shindo S et al., Effects of a moisturizer containing pseudo-ceramide and a eucalyptus extract on sweating function in adult atopic dermatitis: a double-blind, randomized, controlled left-right comparison clinical trial, Journal of Cosmetic Dermatology 2022;21(10):4503-4509 — pseudo-ceramide + eucalyptus moisturizer restored sweating function and barrier in AD adults
A silicone that sits on your skin as an invisible, non-greasy shield. Reduces water loss, protects against irritants (think soap, friction, incontinence), and is FDA-recognised as a skin protectant from 1-30%. The reason your favourite primer feels silky and your barrier cream actually works under makeup.
Beeckman D, Verhaeghe S, Defloor T, et al. A 3-in-1 perineal care washcloth impregnated with dimethicone 3% versus water and pH neutral soap to prevent and treat incontinence-associated dermatitis: a randomized, controlled clinical trial. J Wound Ostomy Continence Nurs. 2011;38(6):627-634.
Saary J, Qureshi R, Palda V, et al. A systematic review of contact dermatitis treatment and prevention. J Am Acad Dermatol. 2005;53(5):845-855. (Barrier creams containing dimethicone prevent irritant contact dermatitis.)
FDA OTC Final Monograph, 21 CFR Part 347 — Skin Protectant Drug Products for Over-the-Counter Human Use; dimethicone listed at section 347.10 as a Category I active ingredient at 1-30%.
+−6 more ingredients
A workhorse hydrator that pulls water into your skin. In nearly every good moisturizer for a reason.
Danby SG et al., Different types of emollient cream exhibit diverse physiological effects on the skin barrier in adults with atopic dermatitis, Clinical and Experimental Dermatology 2022;47(6):1154-1164 — glycerol+urea emollient delivered superior barrier-strengthening and irritant protection
Youssef R et al., Glycerol 85% efficacy on atopic skin and its microbiome: a randomized controlled trial, Journal of Dermatological Treatment 2021;32(7):730-736 — topical glycerol 85% RCT on atopic skin
Evans NJ et al., Human axillary skin condition is improved following incorporation of glycerol into the stratum corneum from an antiperspirant formulation, Archives of Dermatological Research 2017;309(9):739-748 — 4% glycerol penetrated axillary SC, reduced irritation, improved hydration
Exfoliates the surface of your skin to smooth rough texture and fade dullness. The strongest of the AHAs, so start slow.
Liu H et al., Topical agents for acne (covers AHA / fruit-acid arm), Cochrane Database of Systematic Reviews 2020;5:CD011368 — conclusion: clinical benefit is unclear
Sarkar R et al., Comparative Evaluation of Efficacy and Tolerability of Glycolic Acid, Salicylic-Mandelic Acid, and Phytic Acid Combination Peels in Melasma, Dermatologic Surgery 2016;42(3):384-391 — 35% glycolic acid and salicylic-mandelic peels equally effective and safe for melasma in Indian skin
Kubiak M et al., Evaluation of 70% glycolic peels versus 15% trichloroacetic peels for the treatment of photodamaged facial skin in aging women, Dermatologic Surgery 2014;40(8):883-891 — both peels improved photodamaged skin; glycolic acid showed faster hydration recovery
A pure hydrator that holds water in your skin. Makes skin look plumper and smoother almost immediately.
Karabat MU, Tuncer MC. Effects of hyaluronic acid on skin at the cellular level: a systematic review. Rev Assoc Med Bras. 2025;71(8):e20250208. — Systematic review of 45 studies found low-molecular-weight HA stimulates keratinocyte proliferation and migration while high-molecular-weight HA drives skin hydration, supporting topical HA as an effective skin-hydrating and barrier-supporting ingredient.
Bravo B et al., Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence, Dermatology and Therapy 2022;12(12):2657-2680 — HA-based cosmeceuticals reliably improve hydration and signs of skin aging
Lee SG et al., Hyaluronan Oligosaccharides Improve Rosacea-Like Phenotype through Anti-Inflammatory and Epidermal Barrier-Improving Effects, Annals of Dermatology 2020
A gentle Asian-skincare brightener derived from licorice root. Fades dark spots and calms redness, and it's a pregnancy-safe alternative to stronger fade ingredients.
Glabridin Inhibits Melanogenesis and Melanin Transfer via Wnt/beta-Catenin Pathway and Rho Family GTPase-Mediated Dendritic Formation Suppression, Pharmaceuticals (Basel) 2026;19(3) — glabridin (the licorice-root active) suppressed melanin synthesis and keratinocyte melanin transfer in vitro via Wnt/beta-Catenin and Rho-GTPase dendrite suppression
Liu Y et al., Glycyrrhiza glabra extract as a skin-whitening agent: Identification of active components and CRTC1/MITF pathway-inhibition mechanism, Journal of Ethnopharmacology 2025;349:119948 — identifies glabridin as the principal active and maps skin-whitening mechanism via CREB/CRTC1/MITF suppression
Wang JY et al., Preparation of compound liquorice microemulsion gel and its pharmacodynamics evaluation, Zhongguo Zhong Yao Za Zhi (China Journal of Chinese Materia Medica) 2020;45(21):5193-5199 — compound licorice (Glycyrrhiza) microemulsion gel significantly reduced ear swelling and inflammatory infiltration in chronic eczema mouse model
A multitasker that calms redness, evens out skin tone, and helps oily skin balance out. One of the safest do-a-little-of-everything ingredients.
Moro F et al., Skin Cancer Prevention and Antiaging: Role of Nicotinamide, International Journal of Molecular Sciences 2026
Passeron T et al., An Investigator-Blinded, Randomized Trial of a Broad-Spectrum Sunscreen Containing Sclareolide and Niacinamide, Dermatology and Therapy (Heidelberg) 2026
Vergilio MM et al., Topical Formulation with Niacinamide Combined with 5 MHz Ultrasound for Improving Skin Ageing, Current Medicinal Chemistry 2025
Speeds up how fast your skin renews itself so old, dull cells shed faster and fresher skin shows through. Builds collagen over time, smoothing fine lines.
SCCS Revision of the Scientific Opinion on Vitamin A (Retinol, Retinyl Acetate, Retinyl Palmitate), SCCS/1639/21, final version adopted 24-25 October 2022
Chien AL et al. Biomarkers of Tretinoin Precursors and Tretinoin Efficacy in Patients With Moderate to Severe Facial Photodamage: A Randomized Clinical Trial. JAMA Dermatology. 2022;158(8):892-900. doi:10.1001/jamadermatol.2022.1891 — RCT comparing topical retinol precursors vs tretinoin for photoaging; both showed equivalent wrinkle reduction at week 24 with retinol formulation causing 6x less erythema than tretinoin.
MFDS Approved Functional Cosmetic Active — Retinol (anti-wrinkle). Korean Ministry of Food and Drug Safety, Cosmetic Functional Active Ingredient List — listed alongside Adenosine, Retinyl Palmitate, and Polyethoxylated Retinamide in the Korean Functional Cosmetics Codex anti-wrinkle category
Sources: 10 clinical journals and regulatory databases across the US, EU, Korea, Japan, and China. Every entry points to a specific document. See methodology for the full list and what each outcome label means.
Layering conflicts
Ingredients in this product that can react with common actives. Avoid stacking unless noted.
- Tretinoinhigh
Tretinoin + glycolic acid causes significant barrier disruption. Never layer.
- Salicylic Acidhigh
Retinol + salicylic acid can over-exfoliate and damage the barrier. Alternate nights.
- Adapalenemedium
Adapalene + glycolic acid can over-exfoliate. Alternate nights.
- Lactic Acidmedium
Retinol + lactic acid is gentler than glycolic but still alternate nights to be safe.
- Mandelic Acidmedium
Retinol + mandelic acid — alternate nights to preserve barrier integrity.
- Benzoyl Peroxidemedium
Benzoyl peroxide can break down retinol. Use one in the morning and the other at night, or pick a stabilized formula made to combine them.
- Vitamin Clow
Vitamin C and retinol work best at different pH levels. Use vitamin C in the morning and retinol at night.
Similar comparisons
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