Ingredients Exfoliating Mandelic Acid
11Md
Sourced from lab
Tier · Strong evidence
Exfoliating

Mandelic Acid

INCI: Mandelic Acid · Also called: AHA

The slowest, gentlest exfoliating acid. Resurfaces with the least irritation, especially friendly to sensitive and deeper skin tones.

For your skin

The slowest, gentlest exfoliating acid. Resurfaces with the least irritation, especially friendly to sensitive and deeper skin tones.

Want the science? Keep reading ↓

Mechanism of action

Larger-molecule AHA that penetrates more slowly, exfoliating with less irritation than glycolic.

Why we tier this strong

6 cited papers across 3 countries. Multiple positive efficacy results plus regulatory backing. Clears our published bar (Strong = 15+ studies with multiple randomized controlled trials (RCTs), or a single large longitudinal cohort).

4
International
1
United States
1
European Union

Layering matrix

!Combine carefully
  • Retinolmedium

    Retinol + mandelic acid — alternate nights to preserve barrier integrity.

Read the research

Compare with

Cited research

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Ravikumar P et al., Efficacy of Alpha and Beta Hydroxy Acid Chemical Peels in Postacne Pigmentation, Journal of Clinical and Aesthetic Dermatology 2022 — mandelic-acid-containing peels improved postacne hyperpigmentation in a randomized comparison

2022Positive — efficacyPMID:35309278View source ↗
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Dayal S et al., Comparative study of efficacy and safety of 45% mandelic acid versus 30% salicylic acid peels in mild-to-moderate acne vulgaris, Journal of Cosmetic Dermatology 2020 — 45% mandelic acid peels comparably effective and better tolerated than 30% salicylic peels

2020Positive — efficacyPMID:31553119View source ↗
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Sarkar R et al., Comparative study of 35% glycolic acid, 20% salicylic-10% mandelic acid, and phytic acid combination peels in the treatment of active acne, Journal of Cutaneous and Aesthetic Surgery 2019;12(3):158-163

2019Positive — efficacyPMID:31619887View source ↗
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Jacobs SW, Culbertson EJ, Effects of Topical Mandelic Acid Treatment on Facial Skin Viscoelasticity, Facial Plastic Surgery 2018;34(6):651-656 — twice-daily topical mandelic acid for 4 weeks increased lower-eyelid skin elasticity by 25.4%

2018Positive — efficacyPMID:30513536View source ↗
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Kontochristopoulos G, Platsidaki E (Greece), Chemical peels in active acne and acne scars, Clinics in Dermatology 2017;35(2):179-182 — review supporting mandelic-acid-containing peels for active acne and acne scarring

2017Meta-analysis — positivePMID:28274356View source ↗
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Sarkar R et al., Comparative Evaluation of Efficacy and Tolerability of Glycolic Acid, Salicylic Mandelic Acid, and Phytic Acid Combination Peels in Melasma, Dermatologic Surgery 2016;42(3):384-391 — salicylic-mandelic combination peels equally efficacious to 35% glycolic in 90 Indian melasma patients

2016Positive — efficacyPMID:26859648View source ↗

Sources: PubMed · KCI · J-Stage · CNKI · Wanfang · SFD · MFDS · Cochrane · SCCS · CIR. Every entry points to a specific document. See methodology for what each outcome label means.