Ingredients Exfoliating Glycolic Acid
9Gl
Sourced from sugarcane + lab
Tier · Strong evidence
Exfoliating

Glycolic Acid

INCI: Glycolic Acid · Also called: AHA

Exfoliates the surface of your skin to smooth rough texture and fade dullness. The strongest of the AHAs, so start slow.

For your skin

Exfoliates the surface of your skin to smooth rough texture and fade dullness. The strongest of the AHAs, so start slow.

Want the science? Keep reading ↓

Mechanism of action

Smallest alpha hydroxy acid; loosens corneocyte bonds in the stratum corneum to accelerate desquamation.

Why we tier this strong

6 cited papers across 2 countries. Multiple positive efficacy results plus regulatory backing. Clears our published bar (Strong = 15+ studies with multiple randomized controlled trials (RCTs), or a single large longitudinal cohort).

3
International
3
United States

Layering matrix

!Combine carefully
  • Retinol + glycolic acid is a classic barrier-buster. Use on different nights.

  • Tretinoin + glycolic acid causes significant barrier disruption. Never layer.

  • Adapalenemedium

    Adapalene + glycolic acid can over-exfoliate. Alternate nights.

  • AHA + BHA stacking risks over-exfoliation. Use a pre-formulated AHA/BHA product or alternate days.

Read the research

Compare with

Cited research

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Liu H et al., Topical agents for acne (covers AHA / fruit-acid arm), Cochrane Database of Systematic Reviews 2020;5:CD011368 — conclusion: clinical benefit is unclear

2020Meta-analysis — mixedPMID:32356369View source ↗
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Sarkar R et al., Comparative Evaluation of Efficacy and Tolerability of Glycolic Acid, Salicylic-Mandelic Acid, and Phytic Acid Combination Peels in Melasma, Dermatologic Surgery 2016;42(3):384-391 — 35% glycolic acid and salicylic-mandelic peels equally effective and safe for melasma in Indian skin

2016Positive — efficacyPMID:26859648View source ↗
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Kubiak M et al., Evaluation of 70% glycolic peels versus 15% trichloroacetic peels for the treatment of photodamaged facial skin in aging women, Dermatologic Surgery 2014;40(8):883-891 — both peels improved photodamaged skin; glycolic acid showed faster hydration recovery

2014Positive — efficacyPMID:25068547View source ↗
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CIR Final Report on the Safety Assessment of Glycolic Acid and Lactic Acid, their salts and simple esters (Andersen FA), International Journal of Toxicology 1998;17(Suppl 1):1-241

1998Safety assessmentCIR-GlycolicAcidView source ↗
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Stiller MJ et al., Topical 8% glycolic acid and 8% L-lactic acid creams for the treatment of photodamaged skin. A double-blind vehicle-controlled clinical trial, Archives of Dermatology 1996;132(6):631-636 — 76% of glycolic acid users improved at least one grade vs 40% vehicle

1996Positive — efficacyPMID:8651713View source ↗
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Garcia A, Fulton JE Jr, The combination of glycolic acid and hydroquinone or kojic acid for the treatment of melasma and related conditions, Dermatologic Surgery 1996;22(5):443-447 — glycolic acid topical products highly effective in reducing melasma pigment

1996Positive — efficacyPMID:8634807View source ↗

Sources: PubMed · KCI · J-Stage · CNKI · Wanfang · SFD · MFDS · Cochrane · SCCS · CIR. Every entry points to a specific document. See methodology for what each outcome label means.