For your skin
A Korean botanical that calms angry, reactive skin. Especially soothing during flare-ups.
Want the science? Keep reading ↓Mechanism of action
Polyphenol-rich botanical with antioxidant and anti-inflammatory action on irritated skin.
Why we tier this moderate
4 cited papers across 3 countries. The mechanism is well-described and there's at least one controlled trial in the literature, but we tier this Moderate rather than Strong to stay honest about how many specific papers we cite directly.
Layering matrix
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Cited research
Wang Y et al., A review of the research progress on Artemisia argyi Folium: botany, phytochemistry, pharmacological activities, and clinical application, Naunyn-Schmiedeberg's Archives of Pharmacology 2024;397(10):7473-7500 — comprehensive review of 136 compounds; documented anti-inflammatory, antioxidant, antibacterial topical use in eczema/dermatitis
Hirano A et al. (Kyushu University, Furue lab), Antioxidant Artemisia princeps extract enhances the expression of filaggrin and loricrin via the AHR/OVOL1 pathway, International Journal of Molecular Sciences 2017;18(9):1948 — Japanese-authored mechanism study explaining how APE upregulates barrier proteins via AHR/OVOL1; no human efficacy trial yet
Lee JH et al., Topical Application of Eupatilin Ameliorates Atopic Dermatitis-Like Skin Lesions in NC/Nga Mice, Annals of Dermatology 2017;29(1):61-68 — Korean-authored study showing topical eupatilin (Artemisia flavonoid) reduced atopic-dermatitis-like lesions and inflammatory markers
Han HM et al., Ameliorative effects of Artemisia argyi Folium extract on 2,4-dinitrochlorobenzene-induced atopic dermatitis-like lesions in BALB/c mice, Molecular Medicine Reports 2016;14(4):3206-3214 — Korean-authored study; Artemisia argyi extract suppressed Th2 cytokines and improved AD lesions
Sources: PubMed · KCI · J-Stage · CNKI · Wanfang · SFD · MFDS · Cochrane · SCCS · CIR. Every entry points to a specific document. See methodology for what each outcome label means.