Ingredients Centella Asiatica vs Mugwort

Centella Asiatica vs Mugwort

Which is right for your skin?

Bottom line

Both are K-Beauty soothing stars: Centella excels at barrier repair and wound healing; Mugwort is the expert at calming heat and visible redness. Irritated → Centella; red and hot → Mugwort.

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Centella Asiatica
Moderate evidence · 8 studies

Also called "cica," it calms redness, repairs the skin barrier, and speeds up healing. The go-to for irritated or reactive skin.

Anti-inflammatory · Barrier repair
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Mugwort
Moderate evidence · 4 studies

A Korean botanical that calms angry, reactive skin. Especially soothing during flare-ups.

Anti-inflammatory

Can you use Centella Asiatica and Mugwort together?

We have no documented layering conflict between Centella Asiatica and Mugwort. Introduce one at a time and patch-test.

Choose Centella Asiatica if…

You want anti-inflammatory, barrier repair. Also called "cica," it calms redness, repairs the skin barrier, and speeds up healing. The go-to for irritated or reactive skin.

Choose Mugwort if…

You want anti-inflammatory. A Korean botanical that calms angry, reactive skin. Especially soothing during flare-ups.

Cited research

Centella Asiatica
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Su Z et al., The Effectiveness and Safety of a Skin Care Product With Centella asiatica Leaf Extract, Ceramide NP, and Panthenol in Subjects With Sensitive Skin: A Prospective, Observational Study, Journal of Cosmetic Dermatology 2025;24(7):e70324 — Sun Yat-Sen U 4-week study; cream provided rapid relief of facial redness and supported barrier function

2025Positive — efficacyView source ↗
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Cho SY et al., Comparative analysis of bioactive compounds and the anti-inflammatory and wound-healing properties of Centella asiatica, Journal of Applied Biological Chemistry 2025;68:30 — Jeju-grown C. asiatica matched/exceeded imported sources for asiaticoside content; in RAW264.7 + HaCaT models inhibited iNOS/COX-2/IL-1β/IL-6 and accelerated HaCaT wound closure

2025Mechanism onlyView source ↗
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Wang L et al., A two-center randomized controlled trial of a repairing mask as an adjunctive treatment for mild to moderate rosacea, Journal of Cosmetic Dermatology 2024;23(10):3281-3286 — Centella asiatica repairing mask adjunct to minocycline improved IGA, repaired barrier, reduced rosacea symptoms (n=64)

2024Positive — efficacyView source ↗
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Witkowska K et al., Topical Application of Centella asiatica in Wound Healing: Recent Insights into Mechanisms and Clinical Efficacy, Pharmaceutics 2024;16(10):1252 — modern hydrogel and nanostructured Centella delivery systems accelerate wound healing across wound types

2024Meta-analysis — positiveView source ↗
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Park KS, Pharmacological Effects of Centella asiatica on Skin Diseases: Evidence and Possible Mechanisms, Evidence-Based Complementary and Alternative Medicine 2021;2021:5462633 — Centella triterpenes show therapeutic effects across acne, burns, atopic dermatitis and wounds via multiple signaling pathways

2021Meta-analysis — positiveView source ↗
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MFDS Notified Functional Cosmetic Active — Centella Asiatica Extract (skin barrier strengthening). Korean Ministry of Food and Drug Safety — notified active under the Functional Cosmetics Codex barrier-strengthening category; the standardized triterpene fraction (TECA: madecassoside, asiaticoside, asiatic acid, madecassic acid) is the documented active complex

2020Regulatory approvalView source ↗
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Jenwitheesuk K et al., A prospective randomized, controlled, double-blind trial of the efficacy using Centella cream for scar improvement, Evidence-Based Complementary and Alternative Medicine 2018;2018:9525624 — 7% Centella cream produced statistically significant pigmentation-score improvements over 12 weeks on STSG donor sites

2018Positive — efficacyView source ↗
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Bylka W et al., Centella asiatica in dermatology: an overview, Phytotherapy Research 2014;28(8):1117-1124 — pentacyclic triterpenes in Centella enhance wound healing, scar reduction, and burn recovery

2014Mechanism onlyView source ↗
Mugwort
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Wang Y et al., A review of the research progress on Artemisia argyi Folium: botany, phytochemistry, pharmacological activities, and clinical application, Naunyn-Schmiedeberg's Archives of Pharmacology 2024;397(10):7473-7500 — comprehensive review of 136 compounds; documented anti-inflammatory, antioxidant, antibacterial topical use in eczema/dermatitis

2024Mechanism onlyView source ↗
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Hirano A et al. (Kyushu University, Furue lab), Antioxidant Artemisia princeps extract enhances the expression of filaggrin and loricrin via the AHR/OVOL1 pathway, International Journal of Molecular Sciences 2017;18(9):1948 — Japanese-authored mechanism study explaining how APE upregulates barrier proteins via AHR/OVOL1; no human efficacy trial yet

2017Mechanism onlyView source ↗
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Lee JH et al., Topical Application of Eupatilin Ameliorates Atopic Dermatitis-Like Skin Lesions in NC/Nga Mice, Annals of Dermatology 2017;29(1):61-68 — Korean-authored study showing topical eupatilin (Artemisia flavonoid) reduced atopic-dermatitis-like lesions and inflammatory markers

2017Positive — efficacyView source ↗
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Han HM et al., Ameliorative effects of Artemisia argyi Folium extract on 2,4-dinitrochlorobenzene-induced atopic dermatitis-like lesions in BALB/c mice, Molecular Medicine Reports 2016;14(4):3206-3214 — Korean-authored study; Artemisia argyi extract suppressed Th2 cytokines and improved AD lesions

2016Positive — efficacyView source ↗

Every entry points to a specific paper or regulatory document. See methodology for what each outcome label means.

Full Centella Asiatica guide →Full Mugwort guide →