For your skin
A purified compound from the cica (centella) plant, laser-focused on calming inflammation and speeding up how fast skin heals.
Want the science? Keep reading ↓Mechanism of action
Purified triterpene from Centella; reduces inflammatory cytokines and accelerates re-epithelialization.
Why we tier this moderate
5 cited papers across 3 countries. The mechanism is well-described and there's at least one controlled trial in the literature, but we tier this Moderate rather than Strong to stay honest about how many specific papers we cite directly.
Layering matrix
Compare with
Cited research
Bandopadhyay S et al., Therapeutic properties and pharmacological activities of asiaticoside and madecassoside: A review, Journal of Cellular and Molecular Medicine 2023;27(5):593-608 — comprehensive review of wound-healing, anti-inflammatory and regenerative activity
Park KS, Pharmacological Effects of Centella asiatica on Skin Diseases: Evidence and Possible Mechanisms, Evidence-Based Complementary and Alternative Medicine 2021;2021:5462633 — KR-authored review of triterpenes including madecassoside
MFDS Notified Functional Cosmetic Active — Madecassoside (barrier strengthening, as a component of the Centella TECA complex). Korean Ministry of Food and Drug Safety, Functional Cosmetics Codex — one of four standardized triterpenes defining the notified Centella barrier-repair active
Haftek M et al., Clinical, biometric and structural evaluation of the long-term effects of a topical treatment with ascorbic acid and madecassoside in photoaged human skin, Experimental Dermatology 2008;17(11):946-52 — 6-month topical madecassoside + ascorbic acid produced measurable photoaging improvement
Bonté F et al., Influence of asiatic acid, madecassic acid, and asiaticoside on human collagen I synthesis, Planta Medica 1994;60(2):133-5
Sources: PubMed · KCI · J-Stage · CNKI · Wanfang · SFD · MFDS · Cochrane · SCCS · CIR. Every entry points to a specific document. See methodology for what each outcome label means.