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Shop Tocobo Cica Calming Gel Cream
Moisturizer
Tocobo

Cica Calming Gel Cream

~$23.5· 75 ml / 2.37 oz
RednessDrynessAcne

What it's good for

Key actives from our research database. Click any to read the full evidence dossier.

  • Centella AsiaticaModerate evidenceFull dossier ↗

    Also called "cica," it calms redness, repairs the skin barrier, and speeds up recovery. The go-to for irritated or reactive skin.

    Good for: Anti-inflammatory, Barrier repair

  • Hyaluronic AcidStrong evidenceFull dossier ↗

    A pure hydrator that holds water in your skin. Makes skin look plumper and smoother almost immediately.

    Good for: Hydrating

  • NiacinamideStrong evidenceFull dossier ↗

    A multitasker that calms redness, evens out skin tone, and helps oily skin balance out. One of the safest do-a-little-of-everything ingredients.

    Good for: Brightening, Barrier repair, Anti-inflammatory

  • Bifida Ferment LysateModerate evidenceFull dossier ↗

    A probiotic-based ingredient that strengthens your skin's defenses against irritation and environmental stress.

    Good for: Barrier repair, Anti-inflammatory

  • Tea Tree OilModerate evidenceFull dossier ↗

    A natural acne spot-treatment that kills the bacteria behind red, painful pimples. Slower than benzoyl peroxide but with fewer side effects when used at 5%.

    Good for: Anti-acne, Anti-inflammatory

  • AllantoinAnecdotal evidenceFull dossier ↗

    A gentle smoother and skin-soother. Reduces flakiness and helps the surface look more even.

    Good for: Anti-inflammatory, Hydrating

Evidence behind the ingredients

Real citations from our research database, one per tracked active in this product. Click any ingredient name to read its full evidence dossier.

Centella AsiaticaModerate evidence6 citations

Also called "cica," it calms redness, repairs the skin barrier, and speeds up recovery. The go-to for irritated or reactive skin.

Hur N et al., A Randomized, Double-Blind, Placebo-Controlled Trial Assessing the Effects of Oral Centella asiatica Extract on Skin Aging-Related Parameters in Middle-Aged Korean Women, Nutrients 2026

2026Positive (efficacy)PMID:42196964View source ↗

Borowicz KK et al., Geroprotective Potential of Centella asiatica: Modulation of Cellular Aging, Nutrients 2026

2026Mechanism onlyPMID:42280293View source ↗

Witkowska K et al., Topical Application of Centella asiatica in Wound Healing: Recent Insights into Mechanisms and Clinical Efficacy, Pharmaceutics 2024;16(10):1252 — modern hydrogel and nanostructured Centella delivery systems accelerate wound healing across wound types

2024Meta-analysis (positive)PMID:39458583View source ↗
Hyaluronic AcidStrong evidence7 citations

A pure hydrator that holds water in your skin. Makes skin look plumper and smoother almost immediately.

Karabat MU, Tuncer MC. Effects of hyaluronic acid on skin at the cellular level: a systematic review. Rev Assoc Med Bras. 2025;71(8):e20250208. — Systematic review of 45 studies found low-molecular-weight HA stimulates keratinocyte proliferation and migration while high-molecular-weight HA drives skin hydration, supporting topical HA as an effective skin-hydrating and barrier-supporting ingredient.

2025Meta-analysis (positive)PMID:40990743View source ↗

Bravo B et al., Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence, Dermatology and Therapy 2022;12(12):2657-2680 — HA-based cosmeceuticals reliably improve hydration and signs of skin aging

2022Meta-analysis (positive)PMID:36200921View source ↗

Lee SG et al., Hyaluronan Oligosaccharides Improve Rosacea-Like Phenotype through Anti-Inflammatory and Epidermal Barrier-Improving Effects, Annals of Dermatology 2020

2020Mechanism onlyPMID:33911737View source ↗
NiacinamideStrong evidence10 citations

A multitasker that calms redness, evens out skin tone, and helps oily skin balance out. One of the safest do-a-little-of-everything ingredients.

Moro F et al., Skin Cancer Prevention and Antiaging: Role of Nicotinamide, International Journal of Molecular Sciences 2026

2026Mechanism onlyPMID:42278444View source ↗

Passeron T et al., An Investigator-Blinded, Randomized Trial of a Broad-Spectrum Sunscreen Containing Sclareolide and Niacinamide, Dermatology and Therapy (Heidelberg) 2026

2026Positive (efficacy)PMID:41240206View source ↗

Vergilio MM et al., Topical Formulation with Niacinamide Combined with 5 MHz Ultrasound for Improving Skin Ageing, Current Medicinal Chemistry 2025

2025Positive (efficacy)PMID:39171587View source ↗
+3 more ingredients
Bifida Ferment LysateModerate evidence6 citations

A probiotic-based ingredient that strengthens your skin's defenses against irritation and environmental stress.

Zhu X et al., Protective effect of Bifidobacterium animalis CGMCC25262 on HaCaT keratinocytes, International Microbiology 2024;27(5):1417-1428 — B. animalis lysate upregulated HAS-2, AQP3, FLG and reduced RANTES under TNF-α/IFN-γ

2024Mechanism onlyPMID:38278974View source ↗

Wang Y et al., Short-term skin reactions and changes in stratum corneum following different ways of facial sheet mask usage, Journal of Tissue Viability 2024;33(4):831-839 — evaluated topical bifida ferment lysate masks on skin barrier measures

2024Positive (efficacy)PMID:38951050View source ↗

Wang R et al., The pivotal role of Bifida Ferment Lysate on reinforcing the skin barrier function and maintaining homeostasis of skin defenses in vitro, Journal of Cosmetic Dermatology 2023;22(12):3427-3435 — BFL upregulated barrier and antioxidant genes; reduced inflammatory signaling

2023Mechanism onlyPMID:37218728View source ↗
Tea Tree OilModerate evidence6 citations

A natural acne spot-treatment that kills the bacteria behind red, painful pimples. Slower than benzoyl peroxide but with fewer side effects when used at 5%.

Najafi-Taher R et al., A topical gel of tea tree oil nanoemulsion containing adapalene versus adapalene marketed gel in patients with acne vulgaris: a randomized clinical trial, Archives of Dermatological Research 2022;314(7):673-679 — RCT showed tea tree oil + adapalene nanoemulsion gel produced significantly better reduction in total, inflammatory and non-inflammatory acne lesions than standard adapalene

2022Positive (efficacy)PMID:34251536View source ↗

Zambello A et al. Tea tree oil contact sensitization in children. Contact Dermatitis. 2021;84(2):123-124. doi:10.1111/cod.13699 — Documents allergic contact dermatitis from tea tree oil exposure in pediatric patients identified through patch testing; highlights sensitization risk in children.

2021Safety assessmentPMID:32885466View source ↗

Malhi HK, Tu J, Riley TV, Kumarasinghe SP, Hammer KA, Tea tree oil gel for mild to moderate acne; a 12 week uncontrolled, open-label phase II pilot study, Australasian Journal of Dermatology 2017;58(3):205-210

2017Positive (efficacy)PMID:27000386View source ↗
AllantoinAnecdotal evidence6 citations

A gentle smoother and skin-soother. Reduces flakiness and helps the surface look more even.

Xu Z et al., Efficacy and Safety of Topical Compound Heparin Sodium Allantoin Gel for the Treatment of Rosacea, Journal of Cosmetic Dermatology 2025;24(4):e70129 — RCT (n=82, 12 weeks): allantoin gel improved erythema and alleviated itching/burning vs traditional therapy

2025Positive (efficacy)PMID:40177799View source ↗

Tan C et al., The combination of allantoin, bisabolol, D-panthenol and dipotassium glycyrrhizinate mitigates UVB-induced PGE2 synthesis by keratinocytes, International Journal of Cosmetic Science 2024;46(5):691-701 — in vitro: allantoin combination reduced UVB-induced PGE2, IL-1α, IL-6, IL-8, TNFα

2024Mechanism onlyPMID:38433250View source ↗

Saucedo-Acuna RA et al. (Mexico), Characterization and In Vivo Assay of Allantoin-Enriched Pectin Hydrogel for the Treatment of Skin Wounds, International Journal of Molecular Sciences 2023;24(8):7377 — allantoin-pectin hydrogel reduced wound healing time by ~71% with complete closure at day 15 in rat model

2023Mechanism onlyPMID:37108540View source ↗

Sources: 10 clinical journals and regulatory databases across the US, EU, Korea, Japan, and China. Every entry points to a specific document. See methodology for the full list and what each outcome label means.

Full ingredient list

Everything on the package label, not just the tracked actives above.

Fragrance freeDrying alcohol freeSulfates freeParabens free
  • Contains silicones: Dimethicone, Methyl Trimethicone, Pca DimethiconeNo irritancy evidence. CIR rates this safe as used; some shoppers avoid it by preference.
+Show all 43 ingredients

Listed in the order printed on the package. By regulation, ingredients at 1% or higher are listed in descending order by concentration, so the first entry is the largest part of the formula.

  1. Water
  2. Glycerin
  3. Butylene Glycol
  4. Propanediol
  5. Dimethicone
  6. Methyl Trimethicone
  7. Hydrogenated Poly(C6 14 Olefin)
  8. 1,2-Hexanediol
  9. Pca Dimethicone
  10. Pentaerythrityl Tetraethylhexanoate
  11. Cetearyl Alcohol
  12. Glyceryl Stearate Citrate
  13. Acrylates/​C10-30 Alkyl Acrylate Crosspolymer
  14. Tromethamine
  15. Centella Asiatica Leaf Extract
  16. Bifida Ferment Lysate
  17. Lactococcus Ferment Lysate
  18. Lactobacillus Ferment Lysate
  19. Dextrin
  20. Dipropylene Glycol
  21. Niacinamide
  22. Xanthan Gum
  23. Ethylhexylglycerin
  24. Gardenia Florida Fruit Extract
  25. Disodium EDTA
  26. Sorbitan Isostearate
  27. Panthenol
  28. Melaleuca Alternifolia (Tea Tree) Extract
  29. Hydrogenated Lecithin
  30. Asiaticoside
  31. Asiatic Acid
  32. Madecassic Acid
  33. Pinus Densiflora Leaf Extract
  34. Tocopherol
  35. Sodium Hyaluronate
  36. Beta-Glucan
  37. Ceramide NP
  38. Hydroxypropyltrimonium Hyaluronate
  39. Hydrolyzed Hyaluronic Acid
  40. Sodium Acetylated Hyaluronate
  41. Hyaluronic Acid
  42. Hydrolyzed Sodium Hyaluronate
  43. Sodium Hyaluronate Crosspolymer

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