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Essence
Isntree

Hyaluronic Acid Water Essence

~$31.22· 50ml
Dryness

What it's good for

Key actives from our research database. Click any to read the full evidence dossier.

  • NiacinamideStrong evidenceFull dossier ↗

    A multitasker that calms redness, evens out skin tone, and helps oily skin balance out. One of the safest do-a-little-of-everything ingredients.

    Good for: Brightening, Barrier repair, Anti-inflammatory

  • Hyaluronic AcidStrong evidenceFull dossier ↗

    A pure hydrator that holds water in your skin. Makes skin look plumper and smoother almost immediately.

    Good for: Hydrating

  • Beta-GlucanModerate evidenceFull dossier ↗

    A heavy-duty hydrator that also reduces irritation. Often called "better than hyaluronic acid" for sensitive skin.

    Good for: Hydrating, Anti-inflammatory

  • PanthenolModerate evidenceFull dossier ↗

    Pro-vitamin B5. Deeply hydrates and helps repair the skin barrier, calming dry or compromised skin.

    Good for: Hydrating, Barrier repair

  • AdenosineModerate evidenceFull dossier ↗

    A Korean-approved anti-wrinkle ingredient that encourages collagen production for a smoother, firmer look.

    Good for: Anti-aging

  • GlycerinModerate evidenceFull dossier ↗

    A workhorse hydrator that pulls water into your skin. In nearly every good moisturizer for a reason.

    Good for: Hydrating

  • Sodium PCAAnecdotal evidenceFull dossier ↗

    Replenishes one of the actual humectant molecules your own skin makes. Levels drop in eczema and with age, so topping it up genuinely helps dry, dehydrated, or atopic-prone skin feel less tight.

    Good for: Hydrating, Barrier repair

Evidence behind the ingredients

Real citations from our research database, one per tracked active in this product. Click any ingredient name to read its full evidence dossier.

NiacinamideStrong evidence10 citations

A multitasker that calms redness, evens out skin tone, and helps oily skin balance out. One of the safest do-a-little-of-everything ingredients.

Moro F et al., Skin Cancer Prevention and Antiaging: Role of Nicotinamide, International Journal of Molecular Sciences 2026

2026Mechanism onlyPMID:42278444View source ↗

Passeron T et al., An Investigator-Blinded, Randomized Trial of a Broad-Spectrum Sunscreen Containing Sclareolide and Niacinamide, Dermatology and Therapy (Heidelberg) 2026

2026Positive (efficacy)PMID:41240206View source ↗

Vergilio MM et al., Topical Formulation with Niacinamide Combined with 5 MHz Ultrasound for Improving Skin Ageing, Current Medicinal Chemistry 2025

2025Positive (efficacy)PMID:39171587View source ↗
Hyaluronic AcidStrong evidence7 citations

A pure hydrator that holds water in your skin. Makes skin look plumper and smoother almost immediately.

Karabat MU, Tuncer MC. Effects of hyaluronic acid on skin at the cellular level: a systematic review. Rev Assoc Med Bras. 2025;71(8):e20250208. — Systematic review of 45 studies found low-molecular-weight HA stimulates keratinocyte proliferation and migration while high-molecular-weight HA drives skin hydration, supporting topical HA as an effective skin-hydrating and barrier-supporting ingredient.

2025Meta-analysis (positive)PMID:40990743View source ↗

Bravo B et al., Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence, Dermatology and Therapy 2022;12(12):2657-2680 — HA-based cosmeceuticals reliably improve hydration and signs of skin aging

2022Meta-analysis (positive)PMID:36200921View source ↗

Lee SG et al., Hyaluronan Oligosaccharides Improve Rosacea-Like Phenotype through Anti-Inflammatory and Epidermal Barrier-Improving Effects, Annals of Dermatology 2020

2020Mechanism onlyPMID:33911737View source ↗
Beta-GlucanModerate evidence5 citations

A heavy-duty hydrator that also reduces irritation. Often called "better than hyaluronic acid" for sensitive skin.

Feng X et al., Exploring the Properties and Application Potential of beta-Glucan in Skin Care, Food Science and Nutrition 2025;13(4):e70212 — review concludes beta-glucan exhibits antioxidant, anti-inflammatory, barrier repair, and moisturizing bioactivities

2025Mechanism onlyPMID:40291929View source ↗

Kussie HC et al., Avenanthramide and beta-Glucan Therapeutics Accelerate Wound Healing Via Distinct and Nonoverlapping Mechanisms, Advances in Wound Care 2024;13(4):155-166 — in vivo: beta-glucan accelerated wound closure with increased angiogenesis

2024Positive (efficacy)PMID:38299969View source ↗

Cao Y et al., Improving the outcome of treating striae gravidarum by combined therapies using topical β-glucan and 1565-nm non-ablative fractional laser, Journal of Dermatology 2022;49(9):829-836 — RCT; topical beta-glucan twice daily for 12 weeks on stretch marks

2022Positive (efficacy)PMID:35570397View source ↗
+4 more ingredients
PanthenolModerate evidence5 citations

Pro-vitamin B5. Deeply hydrates and helps repair the skin barrier, calming dry or compromised skin.

Gao Y et al., Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment, Journal of Cosmetic Dermatology 2025;24(7):e70223 — double-blind RCT (n=60): panthenol mask decreased erythema, enhanced hydration, repaired barrier vs saline

2025Positive (efficacy)PMID:40613435View source ↗

Cho YS et al., Use of Dexpanthenol for Atopic Dermatitis-Benefits and Recommendations Based on Current Evidence, Journal of Clinical Medicine 2022;11(14):3943 — Korean-authored review; dexpanthenol improves barrier and reduces severity in mild-to-moderate AD

2022Meta-analysis (positive)PMID:35887707View source ↗

Heise R et al., Accelerated wound healing with a dexpanthenol-containing ointment after fractional ablative CO2 laser resurfacing of photo-damaged skin in a randomized prospective clinical trial, Cutaneous and Ocular Toxicology 2019;38(3):274-278 — RCT: dexpanthenol significantly faster wound closure vs petroleum jelly post-laser

2019Positive (efficacy)PMID:30897983View source ↗
AdenosineModerate evidence6 citations

A Korean-approved anti-wrinkle ingredient that encourages collagen production for a smoother, firmer look.

Yang HJ et al., Two-phase delivery using a horse oil and adenosine-loaded dissolving microneedle patch for skin barrier restoration, moisturization, and wrinkle improvement, Journal of Cosmetic Dermatology 2019;18(3):936-943 — Korean clinical study (n=20): adenosine microneedle patches improved elasticity, hydration, dermal density, wrinkles

2019Positive (efficacy)PMID:30160014View source ↗

Kang G et al., Adenosine-loaded dissolving microneedle patches to improve skin wrinkles, dermal density, elasticity and hydration, International Journal of Cosmetic Science 2018;40(2):199-206 — Korean-authored; adenosine microneedle patches matched or exceeded adenosine cream for multiple endpoints

2018Positive (efficacy)PMID:29574973View source ↗

Kim MY et al., Effect of adenosine on melanogenesis in B16 cells and zebrafish, Annals of Dermatology 2014;26(2):209-13 — adenosine suppresses pigmentation via negative regulation of tyrosinase in cellular and zebrafish models

2014Mechanism onlyPMID:24882976View source ↗
GlycerinModerate evidence6 citations

A workhorse hydrator that pulls water into your skin. In nearly every good moisturizer for a reason.

Danby SG et al., Different types of emollient cream exhibit diverse physiological effects on the skin barrier in adults with atopic dermatitis, Clinical and Experimental Dermatology 2022;47(6):1154-1164 — glycerol+urea emollient delivered superior barrier-strengthening and irritant protection

2022Positive (efficacy)PMID:35167133View source ↗

Youssef R et al., Glycerol 85% efficacy on atopic skin and its microbiome: a randomized controlled trial, Journal of Dermatological Treatment 2021;32(7):730-736 — topical glycerol 85% RCT on atopic skin

2021Positive (efficacy)PMID:31869257View source ↗

Evans NJ et al., Human axillary skin condition is improved following incorporation of glycerol into the stratum corneum from an antiperspirant formulation, Archives of Dermatological Research 2017;309(9):739-748 — 4% glycerol penetrated axillary SC, reduced irritation, improved hydration

2017Positive (efficacy)PMID:28889318View source ↗
Sodium PCAAnecdotal evidence4 citations

Replenishes one of the actual humectant molecules your own skin makes. Levels drop in eczema and with age, so topping it up genuinely helps dry, dehydrated, or atopic-prone skin feel less tight.

Novel design of pyrrolidonecarboxylic acid and sodium dilauramidoglutamide lysine complex for targeted drug delivery to human stratum corneum, International Journal of Pharmaceutics 2025

2025Mechanism onlyPMID:40187708View source ↗

Baldwin H, Del Rosso J, Going Beyond Ceramides in Moisturizers: The Role of Natural Moisturizing Factors, Journal of Drugs in Dermatology 2024 — review establishing PCA (pyrrolidone carboxylic acid) as a core skin natural moisturizing factor alongside amino acids, urea, lactate, and electrolytes; essential to barrier function and xerosis treatment

2024Mechanism onlyPMID:38834224View source ↗

Li L et al., Association Between Skin Acid Mantle, Natural Moisturizing Factors, and Antibacterial Activity Against S. aureus in the Stratum Corneum, Clinical Cosmetic and Investigational Dermatology 2023 — PCA and urocanic acid as NMF components contribute to skin antibacterial defense; 1-unit pH drop = 68.1% S. aureus cell death

2023Mechanism onlyPMID:37378303View source ↗

Sources: 10 clinical journals and regulatory databases across the US, EU, Korea, Japan, and China. Every entry points to a specific document. See methodology for the full list and what each outcome label means.

Full ingredient list

Everything on the package label, not just the tracked actives above.

Fragrance freeDrying alcohol freeSulfates freeParabens free
  • Contains silicones: CyclohexasiloxaneNo irritancy evidence. CIR rates this safe as used; some shoppers avoid it by preference.
+Show all 37 ingredients

Listed in the order printed on the package. By regulation, ingredients at 1% or higher are listed in descending order by concentration, so the first entry is the largest part of the formula.

  1. Water
  2. Methylpropanediol
  3. Polyglycerin-3
  4. Glycerin
  5. Caprylic/​Capric Triglyceride
  6. 1,2-Hexanediol
  7. Niacinamide
  8. Cyclohexasiloxane
  9. Ammonium Acryloyldimethyltaurate/​VP Copolymer
  10. Sodium Hyaluronate
  11. Betaine
  12. Xanthan Gum
  13. Trehalose
  14. Panthenol
  15. Butylene Glycol
  16. Sodium PCA
  17. Ethylhexylglycerin
  18. Adenosine
  19. Carbomer
  20. Disodium EDTA
  21. Tromethamine
  22. Polyquaternium-51
  23. Avena Sativa (Oat) Kernel Extract
  24. Beta-Glucan
  25. Hydrogenated Lecithin
  26. Pteris Multifida Extract
  27. Cynara Scolymus (Artichoke) Leaf Extract
  28. Pentylene Glycol
  29. Hyaluronic Acid
  30. Sodium Hyaluronate Crosspolymer
  31. Hydrolyzed Hyaluronic Acid
  32. Ascorbyl Propyl Hyaluronate
  33. Tocopherol
  34. Hydroxypropyltrimonium Hyaluronate
  35. Hydrolyzed Sodium Hyaluronate
  36. Sodium Acetylated Hyaluronate
  37. Opuntia Ficus-Indica Seed Oil

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Not medical advice. GlowPal is educational. Patch-test new products and talk to a qualified healthcare professional before changing your routine, especially if you're pregnant, nursing, or have a diagnosed skin condition. See our terms.