White Truffle Intensive Skin Calming Serum
What it's good for
Key actives from our research database. Click any to read the full evidence dossier.
A Korean-approved anti-wrinkle ingredient that encourages collagen production for a smoother, firmer look.
Good for: Anti-aging
A lightweight Japanese plant oil that hydrates and seals in moisture without feeling heavy.
Good for: Hydrating, Barrier repair
Also called "cica," it calms redness, repairs the skin barrier, and speeds up recovery. The go-to for irritated or reactive skin.
Good for: Anti-inflammatory, Barrier repair
The classic "tea-bag-on-puffy-eyes" botanical. Calms angry skin via well-studied anti-inflammatory pathways, gently. Good for reactive or rosacea-prone complexions.
Good for: Anti-inflammatory, Antioxidant
A fruit-derived AHA that exfoliates and antioxidizes. It shares the same basic mechanism as glycolic and lactic acid but is weaker gram-for-gram; in practice you'll see it doing dual duty (a little exfoliation plus pH stabilisation) in multi-acid toners and serums. When it appears low on an ingredient list, it's adjusting pH; higher up, it's contributing real exfoliation.
Good for: Exfoliating, Antioxidant
A polyphenol from green tea that calms UV-triggered redness and reinforces your sunscreen as a second line of antioxidant defense.
Good for: Antioxidant, Anti-inflammatory, Sun protection
A workhorse hydrator that pulls water into your skin. In nearly every good moisturizer for a reason.
Good for: Hydrating
A pure hydrator that holds water in your skin. Makes skin look plumper and smoother almost immediately.
Good for: Hydrating
A Korean botanical that calms angry, reactive skin. Especially soothing during flare-ups.
Good for: Anti-inflammatory
A "natural skin lightener" with actual clinical-trial backing for melasma. A placebo-controlled study showed real MASI improvement. Sits well alongside vitamin C, alpha-arbutin, or niacinamide in a brightening stack.
Good for: Brightening, Antioxidant
A multitasker that calms redness, evens out skin tone, and helps oily skin balance out. One of the safest do-a-little-of-everything ingredients.
Good for: Brightening, Barrier repair, Anti-inflammatory
A workhorse antioxidant that defends your skin from daily oxidative damage. Pairs especially well with vitamin C, and it's in nearly every good moisturizer for a reason.
Good for: Antioxidant
A botanical astringent backed by real anti-inflammatory evidence. Extracts genuinely calm acne-related inflammation by blocking the same NF-κB pathway that redness-causing cytokines depend on. Honest caveat: most shelf-ready witch hazel toners are distilled water with trace tannin; look for "Hamamelis virginiana extract" rather than "hamamelis water" on the label if you want the active fraction.
Good for: Anti-inflammatory, Anti-acne
Evidence behind the ingredients
Real citations from our research database, one per tracked active in this product. Click any ingredient name to read its full evidence dossier.
A Korean-approved anti-wrinkle ingredient that encourages collagen production for a smoother, firmer look.
Yang HJ et al., Two-phase delivery using a horse oil and adenosine-loaded dissolving microneedle patch for skin barrier restoration, moisturization, and wrinkle improvement, Journal of Cosmetic Dermatology 2019;18(3):936-943 — Korean clinical study (n=20): adenosine microneedle patches improved elasticity, hydration, dermal density, wrinkles
Kang G et al., Adenosine-loaded dissolving microneedle patches to improve skin wrinkles, dermal density, elasticity and hydration, International Journal of Cosmetic Science 2018;40(2):199-206 — Korean-authored; adenosine microneedle patches matched or exceeded adenosine cream for multiple endpoints
Kim MY et al., Effect of adenosine on melanogenesis in B16 cells and zebrafish, Annals of Dermatology 2014;26(2):209-13 — adenosine suppresses pigmentation via negative regulation of tyrosinase in cellular and zebrafish models
A lightweight Japanese plant oil that hydrates and seals in moisture without feeling heavy.
Jiao Y et al., Restorative effects of camellia oil on the skin-barrier function in a model of DNCB-induced atopic dermatitis, European Journal of Histochemistry 2025;69(1):4147 — topical camellia oil improved AD symptoms, upregulated filaggrin, reduced inflammatory infiltration in mouse model
Chaikul P et al., Melanogenesis Inhibitory and Antioxidant Effects of Camellia oleifera Seed Oil, Advanced Pharmaceutical Bulletin 2017;7(3):473-477 — camellia oil demonstrated tyrosinase inhibition, reduced melanin content, antioxidant cellular protection
Kim S et al., Anti-inflammatory activity of Camellia japonica oil, BMB Reports 2012;45(3):177-182 — suppressed pro-inflammatory cytokine and NO production in LPS-stimulated macrophages
Also called "cica," it calms redness, repairs the skin barrier, and speeds up recovery. The go-to for irritated or reactive skin.
Hur N et al., A Randomized, Double-Blind, Placebo-Controlled Trial Assessing the Effects of Oral Centella asiatica Extract on Skin Aging-Related Parameters in Middle-Aged Korean Women, Nutrients 2026
Borowicz KK et al., Geroprotective Potential of Centella asiatica: Modulation of Cellular Aging, Nutrients 2026
Witkowska K et al., Topical Application of Centella asiatica in Wound Healing: Recent Insights into Mechanisms and Clinical Efficacy, Pharmaceutics 2024;16(10):1252 — modern hydrogel and nanostructured Centella delivery systems accelerate wound healing across wound types
+−10 more ingredients
The classic "tea-bag-on-puffy-eyes" botanical. Calms angry skin via well-studied anti-inflammatory pathways, gently. Good for reactive or rosacea-prone complexions.
Essential Oil of Matricaria chamomilla Alleviates Psoriatic-Like Skin Inflammation by Inhibiting PI3K/Akt/mTOR and p38MAPK Signaling Pathway, Clinical Cosmetic and Investigational Dermatology 2024
Comparative analysis of whole plant, flower and root extracts of Chamomilla recutita L. (Germany), Frontiers in Immunology 2024
Xu J et al., Therapeutic effects of chamomile volatile oil nanoemulsion/Bletilla striata polysaccharides gels on atopic dermatitis, International Journal of Biological Macromolecules 2024 — topical chamomile volatile oil nanoemulsion (19.07 nm) reduced skin damage, epidermal thickness, and mast cell infiltration in atopic dermatitis mice; rebalanced Th1/Th2
A fruit-derived AHA that exfoliates and antioxidizes. It shares the same basic mechanism as glycolic and lactic acid but is weaker gram-for-gram; in practice you'll see it doing dual duty (a little exfoliation plus pH stabilisation) in multi-acid toners and serums. When it appears low on an ingredient list, it's adjusting pH; higher up, it's contributing real exfoliation.
Tang SC, Yang JH. Dual Effects of Alpha-Hydroxy Acids on the Skin. Molecules. 2018;23(4):863.
Yamamoto Y, Uede K, Yonei N, Kishioka A, Ohtani T, Furukawa F. Effects of alpha-hydroxy acids on the human skin of Japanese subjects: the rationale for chemical peeling. Journal of Dermatology. 2006 Jan;33(1):16-22. — Clinical-mechanistic study in Japanese subjects demonstrating AHA (including citric acid class) keratolytic and epidermal renewal effects as rationale for chemical peeling.
Bernstein EF, Underhill CB, Lakkakorpi J, et al. Citric acid increases viable epidermal thickness and glycosaminoglycan content of sun-damaged skin. Dermatologic Surgery. 1997 Aug;23(8):689-694. — Mechanistic study showing topical citric acid increased viable epidermal thickness and dermal glycosaminoglycans in sun-damaged skin, similar to glycolic acid and retinoic acid.
A polyphenol from green tea that calms UV-triggered redness and reinforces your sunscreen as a second line of antioxidant defense.
Detudom P, Kamanamool N, Paichitrojjana A, Udompataikul P, Udompataikul M, Efficacy of anti-sebum moisturizing cream containing 2% l-carnitine and 5% epigallocatechin gallate in seborrhea, Journal of Cosmetic Dermatology 2023;22(11):3058-3064 — Thai RCT showed EGCG-containing cream significantly reduced sebum and improved hydration in seborrhea
Ud-Din S et al., A Double-Blind, Randomized Trial Shows the Role of Zonal Priming and Direct Topical Application of Epigallocatechin-3-Gallate in the Modulation of Cutaneous Scarring in Human Skin, Journal of Investigative Dermatology 2019;139(8):1680-1690 — topical EGCG reduced scar thickness weeks 1-3 and increased elasticity at week 4 vs placebo
Kim YR et al., Clinical Evaluation of a New-Formula Shampoo for Scalp Seborrheic Dermatitis Containing Rosa centifolia + EGCG: A Randomized Double-Blind Controlled Study, Annals of Dermatology 2014;26(6):733-8 — EGCG-containing shampoo matched ketoconazole and zinc pyrithione efficacy; faster erythema response than 1% zinc pyrithione
A workhorse hydrator that pulls water into your skin. In nearly every good moisturizer for a reason.
Danby SG et al., Different types of emollient cream exhibit diverse physiological effects on the skin barrier in adults with atopic dermatitis, Clinical and Experimental Dermatology 2022;47(6):1154-1164 — glycerol+urea emollient delivered superior barrier-strengthening and irritant protection
Youssef R et al., Glycerol 85% efficacy on atopic skin and its microbiome: a randomized controlled trial, Journal of Dermatological Treatment 2021;32(7):730-736 — topical glycerol 85% RCT on atopic skin
Evans NJ et al., Human axillary skin condition is improved following incorporation of glycerol into the stratum corneum from an antiperspirant formulation, Archives of Dermatological Research 2017;309(9):739-748 — 4% glycerol penetrated axillary SC, reduced irritation, improved hydration
A pure hydrator that holds water in your skin. Makes skin look plumper and smoother almost immediately.
Karabat MU, Tuncer MC. Effects of hyaluronic acid on skin at the cellular level: a systematic review. Rev Assoc Med Bras. 2025;71(8):e20250208. — Systematic review of 45 studies found low-molecular-weight HA stimulates keratinocyte proliferation and migration while high-molecular-weight HA drives skin hydration, supporting topical HA as an effective skin-hydrating and barrier-supporting ingredient.
Bravo B et al., Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence, Dermatology and Therapy 2022;12(12):2657-2680 — HA-based cosmeceuticals reliably improve hydration and signs of skin aging
Lee SG et al., Hyaluronan Oligosaccharides Improve Rosacea-Like Phenotype through Anti-Inflammatory and Epidermal Barrier-Improving Effects, Annals of Dermatology 2020
A Korean botanical that calms angry, reactive skin. Especially soothing during flare-ups.
Wang Y et al., A review of the research progress on Artemisia argyi Folium: botany, phytochemistry, pharmacological activities, and clinical application, Naunyn-Schmiedeberg's Archives of Pharmacology 2024;397(10):7473-7500 — comprehensive review of 136 compounds; documented anti-inflammatory, antioxidant, antibacterial topical use in eczema/dermatitis
Hirano A et al. (Kyushu University, Furue lab), Antioxidant Artemisia princeps extract enhances the expression of filaggrin and loricrin via the AHR/OVOL1 pathway, International Journal of Molecular Sciences 2017;18(9):1948 — Japanese-authored mechanism study explaining how APE upregulates barrier proteins via AHR/OVOL1; no human efficacy trial yet
Lee JH et al., Topical Application of Eupatilin Ameliorates Atopic Dermatitis-Like Skin Lesions in NC/Nga Mice, Annals of Dermatology 2017;29(1):61-68 — Korean-authored study showing topical eupatilin (Artemisia flavonoid) reduced atopic-dermatitis-like lesions and inflammatory markers
A "natural skin lightener" with actual clinical-trial backing for melasma. A placebo-controlled study showed real MASI improvement. Sits well alongside vitamin C, alpha-arbutin, or niacinamide in a brightening stack.
Prasawang N, Sutjarit N, Sitthipunya A, et al. Inhibition of Tyrosinase and Melanogenesis by a White Mulberry Fruit Extract. International Journal of Molecular Sciences. 2025 Aug 6;26(15):7589. — Demonstrated dose-dependent inhibition of tyrosinase activity and melanogenesis by white mulberry crude extract in B16F10 cells and zebrafish embryos without cytotoxicity.
Goelzer Neto CF et al., Natural sources of melanogenic inhibitors: A systematic review, International Journal of Cosmetic Science 2022;44(2):143-153 — SR identifying Morus alba (mulberry) as a notable melanogenesis inhibitor
Zhang L et al., Moraceae Plants with Tyrosinase Inhibitory Activity: A Review, Mini Reviews in Medicinal Chemistry 2017;17(13):1148-1157 — Morus alba and related Moraceae compounds demonstrate enzymatic tyrosinase inhibition and clinical whitening effects competitive with available depigmenting agents
A multitasker that calms redness, evens out skin tone, and helps oily skin balance out. One of the safest do-a-little-of-everything ingredients.
Moro F et al., Skin Cancer Prevention and Antiaging: Role of Nicotinamide, International Journal of Molecular Sciences 2026
Passeron T et al., An Investigator-Blinded, Randomized Trial of a Broad-Spectrum Sunscreen Containing Sclareolide and Niacinamide, Dermatology and Therapy (Heidelberg) 2026
Vergilio MM et al., Topical Formulation with Niacinamide Combined with 5 MHz Ultrasound for Improving Skin Ageing, Current Medicinal Chemistry 2025
A workhorse antioxidant that defends your skin from daily oxidative damage. Pairs especially well with vitamin C, and it's in nearly every good moisturizer for a reason.
Neves JR et al., Efficacy of a topical serum containing L-ascorbic acid, neohesperidin, pycnogenol, tocopherol, and hyaluronic acid in relation to skin aging signs, Journal of Cosmetic Dermatology 2022;21(10):4462-4469 — tocopherol-containing antioxidant serum reduced pollution-induced damage and improved aging signs
Warshaw EM et al., Patch Testing With Tocopherol and Tocopherol Acetate: The North American Contact Dermatitis Group Experience, 2001 to 2016, Dermatitis 2021;32(5):308-318 — 15-year NACDG data: positive patch-test reactions to tocopherol rare given widespread cosmetic use
Lin FH et al., Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin, Journal of Investigative Dermatology 2005;125(4):826-832 — ferulic acid + vit C + vit E combo doubled photoprotection vs C+E alone (cross-listed; same paper cited for Ferulic Acid and Vit C)
A botanical astringent backed by real anti-inflammatory evidence. Extracts genuinely calm acne-related inflammation by blocking the same NF-κB pathway that redness-causing cytokines depend on. Honest caveat: most shelf-ready witch hazel toners are distilled water with trace tannin; look for "Hamamelis virginiana extract" rather than "hamamelis water" on the label if you want the active fraction.
Liu X, Hage TW, Chen LC, Wang EHC, Liao IC, Goldberg J, et al. Revealing the Therapeutic Potential: Investigating the Impact of a Novel Witch Hazel Formula on Anti-Inflammation and Antioxidation. Journal of Cosmetic Dermatology. 2025 Feb. — Clinical evaluation of a novel witch hazel formula demonstrating anti-inflammatory and antioxidant effects on skin.
Wojciak M, Pacuła W, Sowa I, Feldo M, Graczyk F, Załuski D. Hamamelis virginiana L. in Skin Care: A Review of Its Pharmacological Properties and Cosmetological Applications. Molecules. 2025 Jun 26;30(13):2744. — Narrative review of pharmacological properties and skin care applications of Hamamelis virginiana.
Piazza S, Martinelli G, Vrhovsek U, Masuero D, Fumagalli M, Magnavacca A, et al. Anti-Inflammatory and Anti-Acne Effects of Hamamelis virginiana Bark in Human Keratinocytes. Antioxidants. 2022;11(6):1119.
Sources: 10 clinical journals and regulatory databases across the US, EU, Korea, Japan, and China. Every entry points to a specific document. See methodology for the full list and what each outcome label means.
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