Tracked ingredients
Key actives from our research database. Click any to read the full evidence dossier.
Evidence behind the ingredients
Real citations from our research database — one per tracked active in this product. Click any ingredient name to read its full evidence dossier.
Also called "cica," it calms redness, repairs the skin barrier, and speeds up healing. The go-to for irritated or reactive skin.
Su Z et al., The Effectiveness and Safety of a Skin Care Product With Centella asiatica Leaf Extract, Ceramide NP, and Panthenol in Subjects With Sensitive Skin: A Prospective, Observational Study, Journal of Cosmetic Dermatology 2025;24(7):e70324 — Sun Yat-Sen U 4-week study; cream provided rapid relief of facial redness and supported barrier function
Cho SY et al., Comparative analysis of bioactive compounds and the anti-inflammatory and wound-healing properties of Centella asiatica, Journal of Applied Biological Chemistry 2025;68:30 — Jeju-grown C. asiatica matched/exceeded imported sources for asiaticoside content; in RAW264.7 + HaCaT models inhibited iNOS/COX-2/IL-1β/IL-6 and accelerated HaCaT wound closure
Wang L et al., A two-center randomized controlled trial of a repairing mask as an adjunctive treatment for mild to moderate rosacea, Journal of Cosmetic Dermatology 2024;23(10):3281-3286 — Centella asiatica repairing mask adjunct to minocycline improved IGA, repaired barrier, reduced rosacea symptoms (n=64)
Pro-vitamin B5. Deeply hydrates and helps repair the skin barrier, calming dry or compromised skin.
Gao Y et al., Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment, Journal of Cosmetic Dermatology 2025;24(7):e70223 — double-blind RCT (n=60): panthenol mask decreased erythema, enhanced hydration, repaired barrier vs saline
Cho YS et al., Use of Dexpanthenol for Atopic Dermatitis-Benefits and Recommendations Based on Current Evidence, Journal of Clinical Medicine 2022;11(14):3943 — Korean-authored review; dexpanthenol improves barrier and reduces severity in mild-to-moderate AD
Heise R et al., Accelerated wound healing with a dexpanthenol-containing ointment after fractional ablative CO2 laser resurfacing of photo-damaged skin in a randomized prospective clinical trial, Cutaneous and Ocular Toxicology 2019;38(3):274-278 — RCT: dexpanthenol significantly faster wound closure vs petroleum jelly post-laser
A gentle smoother and skin-soother. Reduces flakiness and helps the surface look more even.
Xu Z et al., Efficacy and Safety of Topical Compound Heparin Sodium Allantoin Gel for the Treatment of Rosacea, Journal of Cosmetic Dermatology 2025;24(4):e70129 — RCT (n=82, 12 weeks): allantoin gel improved erythema and alleviated itching/burning vs traditional therapy
Tan C et al., The combination of allantoin, bisabolol, D-panthenol and dipotassium glycyrrhizinate mitigates UVB-induced PGE2 synthesis by keratinocytes, International Journal of Cosmetic Science 2024;46(5):691-701 — in vitro: allantoin combination reduced UVB-induced PGE2, IL-1α, IL-6, IL-8, TNFα
Saucedo-Acuna RA et al. (Mexico), Characterization and In Vivo Assay of Allantoin-Enriched Pectin Hydrogel for the Treatment of Skin Wounds, International Journal of Molecular Sciences 2023;24(8):7377 — allantoin-pectin hydrogel reduced wound healing time by ~71% with complete closure at day 15 in rat model
+−2 more ingredients
A polyphenol from green tea that calms UV-triggered redness and reinforces your sunscreen as a second line of antioxidant defense.
Detudom P, Kamanamool N, Paichitrojjana A, Udompataikul P, Udompataikul M, Efficacy of anti-sebum moisturizing cream containing 2% l-carnitine and 5% epigallocatechin gallate in seborrhea, Journal of Cosmetic Dermatology 2023;22(11):3058-3064 — Thai RCT showed EGCG-containing cream significantly reduced sebum and improved hydration in seborrhea
Ud-Din S et al., A Double-Blind, Randomized Trial Shows the Role of Zonal Priming and Direct Topical Application of Epigallocatechin-3-Gallate in the Modulation of Cutaneous Scarring in Human Skin, Journal of Investigative Dermatology 2019;139(8):1680-1690 — topical EGCG reduced scar thickness weeks 1-3 and increased elasticity at week 4 vs placebo
Shin S et al., Epigallocatechin Gallate-Mediated Alteration of the MicroRNA Expression Profile in DHT-Treated Human Dermal Papilla Cells, Annals of Dermatology 2016;28(3):327-34 — EGCG altered miRNA expression to protect dermal papilla cells from DHT-induced death, oxidative stress, and senescence (hair-loss mechanism)
A Korean-skincare staple that hydrates, soothes, and helps surface damage heal faster. Especially nice on dehydrated or post-acne skin.
Puaratanaarunkon T et al., Efficacy and safety of a facial serum containing snail secretion filtrate, Calendula officinalis, and Glycyrrhiza glabra root extract in the treatment of maskne: A randomized placebo-controlled study, Journal of Cosmetic Dermatology 2022;21(10):4470-4478 — 12-week RCT (n=66): snail-secretion-filtrate serum significantly reduced inflammatory acne lesions
Lim DJ et al., Efficacy and safety of a new cosmeceutical regimen based on the combination of snail secretion filtrate and snail egg extract to improve signs of skin aging, Journal of Clinical and Aesthetic Dermatology 2020;13(3):31-38 — 3-month RCT in women 45-65 showed significant improvements in roughness, firmness, elasticity vs vehicle
Fabi SG et al., The Effects of Filtrate of the Secretion of the Cryptomphalus Aspersa on Photoaged Skin, Journal of Drugs in Dermatology 2013;12(4):453-457 — 12-week vehicle-controlled split-face study; significant improvement in fine lines and periorbital wrinkles vs placebo
Sources: PubMed · KCI · J-Stage · CNKI · Wanfang · SFD · MFDS · Cochrane · SCCS · CIR. Every entry points to a specific document. See methodology for what each outcome label means.
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