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Ingredients Hydrating Snail Mucin
23Sm
Sourced from snail
Tier · Moderate evidence
Hydrating · Barrier repair

Snail Mucin

INCI: Snail Secretion Filtrate · Also called: SSF, Snail Filtrate

A Korean-skincare staple that hydrates, soothes, and helps surface damage recover faster. Especially nice on dehydrated or post-acne skin.

For your skin

A Korean-skincare staple that hydrates, soothes, and helps surface damage recover faster. Especially nice on dehydrated or post-acne skin.

Want the science? Keep reading ↓

Mechanism of action

Glycoprotein-rich filtrate that delivers humectants, allantoin, and glycolic acid for hydration and repair.

Why we tier this moderate

6 cited papers across 2 countries. The mechanism is well-described and there's at least one controlled trial in the literature, but we tier this Moderate rather than Strong to stay honest about how many specific papers we cite directly.

5
International
1
United States

Layering matrix

Read the research

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Cited research

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Sekar D et al., From Slime to Sublime: The Impact of Snail Mucin on Scar Therapy and Wound Healing in Dermatology, Cutaneous and Ocular Toxicology 2025

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Puaratanaarunkon T et al., Efficacy and safety of a facial serum containing snail secretion filtrate, Calendula officinalis, and Glycyrrhiza glabra root extract in the treatment of maskne: A randomized placebo-controlled study, Journal of Cosmetic Dermatology 2022;21(10):4470-4478 — 12-week RCT (n=66): snail-secretion-filtrate serum significantly reduced inflammatory acne lesions

2022Positive (efficacy)PMID:35763437View source ↗
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McDermott M et al., Advancing Discovery of Snail Mucins Function and Application, Frontiers in Bioengineering and Biotechnology 2021

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Lim DJ et al., Efficacy and safety of a new cosmeceutical regimen based on the combination of snail secretion filtrate and snail egg extract to improve signs of skin aging, Journal of Clinical and Aesthetic Dermatology 2020;13(3):31-38 — 3-month RCT in women 45-65 showed significant improvements in roughness, firmness, elasticity vs vehicle

2020Positive (efficacy)PMID:32308795View source ↗
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Fabi SG et al., The Effects of Filtrate of the Secretion of the Cryptomphalus Aspersa on Photoaged Skin, Journal of Drugs in Dermatology 2013;12(4):453-457 — 12-week vehicle-controlled split-face study; significant improvement in fine lines and periorbital wrinkles vs placebo

2013Positive (efficacy)PMID:23652894View source ↗
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Iglesias-de la Cruz MC et al., A secretion of the mollusc Cryptomphalus aspersa promotes proliferation, migration and survival of keratinocytes and dermal fibroblasts in vitro, International Journal of Cosmetic Science 2012;34(2):183-189 — mechanistic basis for SCA's regenerative skin effects

Sources: 10 clinical journals and regulatory databases across the US, EU, Korea, Japan, and China. Every entry points to a specific document. See methodology for the full list and what each outcome label means.