Shop Patchology Serve Chilled Rose Hydrating Under Eye Patches with Hyaluronic Acid 5 Pairs
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Serve Chilled Rose Hydrating Under Eye Patches with Hyaluronic Acid 5 Pairs

~$18
RednessDrynessRadiance

Evidence behind the ingredients

Real citations from our research database — one per tracked active in this product. Click any ingredient name to read its full evidence dossier.

GlycerinModerate evidence4 citations

A workhorse hydrator that pulls water into your skin. In nearly every good moisturizer for a reason.

Danby SG et al., Different types of emollient cream exhibit diverse physiological effects on the skin barrier in adults with atopic dermatitis, Clinical and Experimental Dermatology 2022;47(6):1154-1164 — glycerol+urea emollient delivered superior barrier-strengthening and irritant protection

2022Positive — efficacyPMID:35167133View source ↗

Evans NJ et al., Human axillary skin condition is improved following incorporation of glycerol into the stratum corneum from an antiperspirant formulation, Archives of Dermatological Research 2017;309(9):739-748 — 4% glycerol penetrated axillary SC, reduced irritation, improved hydration

2017Positive — efficacyPMID:28889318View source ↗

Fluhr JW et al., Glycerol and the skin: holistic approach to its origin and functions, British Journal of Dermatology 2008;159(1):23-34 — improves xerosis and barrier function

2008Positive — efficacyPMID:18510666View source ↗
Centella AsiaticaModerate evidence9 citations

Also called "cica," it calms redness, repairs the skin barrier, and speeds up healing. The go-to for irritated or reactive skin.

Hur N et al., A Randomized, Double-Blind, Placebo-Controlled Trial Assessing the Effects of Oral Centella asiatica Extract on Skin Aging-Related Parameters in Middle-Aged Korean Women, Nutrients 2026

2026Positive — efficacyPMID:42196964View source ↗

Borowicz KK et al., Geroprotective Potential of Centella asiatica: Modulation of Cellular Aging, Nutrients 2026

2026Mechanism onlyPMID:42280293View source ↗

Su Z et al., The Effectiveness and Safety of a Skin Care Product With Centella asiatica Leaf Extract, Ceramide NP, and Panthenol in Subjects With Sensitive Skin: A Prospective, Observational Study, Journal of Cosmetic Dermatology 2025;24(7):e70324 — Sun Yat-Sen U 4-week study; cream provided rapid relief of facial redness and supported barrier function

2025Positive — efficacyPMID:40682399View source ↗
ChamomileModerate evidence5 citations

The classic "tea-bag-on-puffy-eyes" botanical. Calms angry skin via the same anti-inflammatory pathways psoriasis drugs target, just gentler. Good for reactive or rosacea-prone complexions.

Essential Oil of Matricaria chamomilla Alleviates Psoriatic-Like Skin Inflammation by Inhibiting PI3K/Akt/mTOR and p38MAPK Signaling Pathway, Clinical Cosmetic and Investigational Dermatology 2024

2024Mechanism onlyPMID:38222858View source ↗

Phytochemical, Technological, and Pharmacological Study on the Galenic Dry Extracts Prepared from German Chamomile Flowers (Romania), Plants 2024

2024Mechanism onlyPMID:38337883View source ↗

Comparative analysis of whole plant, flower and root extracts of Chamomilla recutita L. (Germany), Frontiers in Immunology 2024

2024Mechanism onlyPMID:38720895View source ↗
+3 more ingredients
ResveratrolModerate evidence5 citations

A grape-derived antioxidant that defends skin from daily oxidative damage and helps even out tone. Often paired with vitamins C and E in nighttime serums.

Shi Y, Shen C, Zhang W, Efficacy and safety of a topical skincare regimen containing CE Ferulic serum and resveratrol BE serum following ablative fractional CO2 laser treatment, Journal of the European Academy of Dermatology and Venereology 2024;38 Suppl 6:18-25 — split-face RCT, resveratrol-containing serum reduced erythema and accelerated wound healing post-laser

2024Positive — efficacyPMID:38828801View source ↗

Boo YC, Human Skin Lightening Efficacy of Resveratrol and Its Analogs: From in Vitro Studies to Cosmetic Applications, Antioxidants (Basel) 2019;8(9):332

2019Mechanism onlyPMID:31443469View source ↗

Farris P, Zeichner J, Berson D, Efficacy and Tolerability of a Skin Brightening/Anti-Aging Cosmeceutical Containing Retinol 0.5%, Niacinamide, Hexylresorcinol, and Resveratrol, Journal of Drugs in Dermatology 2016;15(7):863-8

2016Positive — efficacyPMID:27391637View source ↗
Hyaluronic AcidStrong evidence7 citations

A pure hydrator that holds water in your skin. Makes skin look plumper and smoother almost immediately.

Bravo B et al., Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence, Dermatology and Therapy 2022;12(12):2657-2680 — HA-based cosmeceuticals reliably improve hydration and signs of skin aging

2022Meta-analysis — positivePMID:36200921View source ↗

Lee SG et al., Hyaluronan Oligosaccharides Improve Rosacea-Like Phenotype through Anti-Inflammatory and Epidermal Barrier-Improving Effects, Annals of Dermatology 2020

2020Mechanism onlyPMID:33911737View source ↗

An JH et al., Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin, Annals of Dermatology 2019;31(3):263-271 — cross-linked HA microneedle patches improved wrinkles on Korean skin with minimal discomfort

2019Positive — efficacyPMID:33911590View source ↗
AllantoinModerate evidence6 citations

A gentle smoother and skin-soother. Reduces flakiness and helps the surface look more even.

Xu Z et al., Efficacy and Safety of Topical Compound Heparin Sodium Allantoin Gel for the Treatment of Rosacea, Journal of Cosmetic Dermatology 2025;24(4):e70129 — RCT (n=82, 12 weeks): allantoin gel improved erythema and alleviated itching/burning vs traditional therapy

2025Positive — efficacyPMID:40177799View source ↗

Tan C et al., The combination of allantoin, bisabolol, D-panthenol and dipotassium glycyrrhizinate mitigates UVB-induced PGE2 synthesis by keratinocytes, International Journal of Cosmetic Science 2024;46(5):691-701 — in vitro: allantoin combination reduced UVB-induced PGE2, IL-1α, IL-6, IL-8, TNFα

2024Mechanism onlyPMID:38433250View source ↗

Saucedo-Acuna RA et al. (Mexico), Characterization and In Vivo Assay of Allantoin-Enriched Pectin Hydrogel for the Treatment of Skin Wounds, International Journal of Molecular Sciences 2023;24(8):7377 — allantoin-pectin hydrogel reduced wound healing time by ~71% with complete closure at day 15 in rat model

2023Mechanism onlyPMID:37108540View source ↗

Sources: PubMed · KCI · J-Stage · CNKI · Wanfang · SFD · MFDS · Cochrane · SCCS · CIR. Every entry points to a specific document. See methodology for what each outcome label means.

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