For your skin
A grape-derived antioxidant that defends skin from daily oxidative damage and helps even out tone. Often paired with vitamins C and E in nighttime serums.
Want the science? Keep reading ↓Mechanism of action
Polyphenolic stilbene that scavenges reactive oxygen species, activates SIRT1, and inhibits tyrosinase and downstream melanogenic signaling.
Why we tier this moderate
6 cited papers across 4 countries. The mechanism is well-described and there's at least one controlled trial in the literature, but we tier this Moderate rather than Strong to stay honest about how many specific papers we cite directly.
Cited research
Shi Y, Shen C, Zhang W, Efficacy and safety of a topical skincare regimen containing CE Ferulic serum and resveratrol BE serum following ablative fractional CO2 laser treatment, Journal of the European Academy of Dermatology and Venereology 2024;38 Suppl 6:18-25 — split-face RCT, resveratrol-containing serum reduced erythema and accelerated wound healing post-laser
Hecker A et al., The impact of resveratrol on skin wound healing, scarring, and aging, International Wound Journal 2022;19(1):9-28 — review of resveratrol's dermatological effects on wound healing, scarring, and photoaging
Lin MH et al., The bioactivities of resveratrol and its naturally occurring derivatives on skin, Journal of Food and Drug Analysis 2021;29(1):15-38 — review of cutaneous resveratrol activity in photoaging, melanogenesis, and dermatitis
Boo YC, Human Skin Lightening Efficacy of Resveratrol and Its Analogs: From in Vitro Studies to Cosmetic Applications, Antioxidants (Basel) 2019;8(9):332
Farris P, Zeichner J, Berson D, Efficacy and Tolerability of a Skin Brightening/Anti-Aging Cosmeceutical Containing Retinol 0.5%, Niacinamide, Hexylresorcinol, and Resveratrol, Journal of Drugs in Dermatology 2016;15(7):863-8
Farris P, Yatskayer M, Chen N, Krol Y, Oresajo C, Evaluation of efficacy and tolerance of a nighttime topical antioxidant containing resveratrol, baicalin, and vitamin E for treatment of mild to moderately photodamaged skin, Journal of Drugs in Dermatology 2014;13(12):1467-72 — 12-week clinical trial showed improvement in fine lines, firmness, elasticity, hyperpigmentation, radiance and ~19% dermal thickness gain
Sources: 10 clinical journals and regulatory databases across the US, EU, Korea, Japan, and China. Every entry points to a specific document. See methodology for the full list and what each outcome label means.