Serum No. 1
What it's good for
Key actives from our research database. Click any to read the full evidence dossier.
A workhorse hydrator that pulls water into your skin. In nearly every good moisturizer for a reason.
Good for: Hydrating
A pure hydrator that holds water in your skin. Makes skin look plumper and smoother almost immediately.
Good for: Hydrating
An essential fatty acid your sebum runs short on if you're acne-prone, and topping it up topically literally shrinks clogged pores. Also rebuilds the lipid mortar between skin cells. Found concentrated in safflower, hemp, and rosehip oils.
Good for: Barrier repair, Anti-acne
A staple in Hanbang (traditional Korean medicine) skincare. It's packed with antioxidants and ginsenosides that help firm the skin, boost circulation, and defend against environmental aging.
Good for: Anti-aging, Antioxidant, Barrier repair
Pro-vitamin B5. Deeply hydrates and helps repair the skin barrier, calming dry or compromised skin.
Good for: Hydrating, Barrier repair
Goes into your pores and dissolves the oil and dead skin clogging them. Best for blackheads, whiteheads, and oily, acne-prone skin.
Good for: Anti-acne, Exfoliating
Evidence behind the ingredients
Real citations from our research database, one per tracked active in this product. Click any ingredient name to read its full evidence dossier.
A workhorse hydrator that pulls water into your skin. In nearly every good moisturizer for a reason.
Danby SG et al., Different types of emollient cream exhibit diverse physiological effects on the skin barrier in adults with atopic dermatitis, Clinical and Experimental Dermatology 2022;47(6):1154-1164 — glycerol+urea emollient delivered superior barrier-strengthening and irritant protection
Youssef R et al., Glycerol 85% efficacy on atopic skin and its microbiome: a randomized controlled trial, Journal of Dermatological Treatment 2021;32(7):730-736 — topical glycerol 85% RCT on atopic skin
Evans NJ et al., Human axillary skin condition is improved following incorporation of glycerol into the stratum corneum from an antiperspirant formulation, Archives of Dermatological Research 2017;309(9):739-748 — 4% glycerol penetrated axillary SC, reduced irritation, improved hydration
A pure hydrator that holds water in your skin. Makes skin look plumper and smoother almost immediately.
Karabat MU, Tuncer MC. Effects of hyaluronic acid on skin at the cellular level: a systematic review. Rev Assoc Med Bras. 2025;71(8):e20250208. — Systematic review of 45 studies found low-molecular-weight HA stimulates keratinocyte proliferation and migration while high-molecular-weight HA drives skin hydration, supporting topical HA as an effective skin-hydrating and barrier-supporting ingredient.
Bravo B et al., Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence, Dermatology and Therapy 2022;12(12):2657-2680 — HA-based cosmeceuticals reliably improve hydration and signs of skin aging
Lee SG et al., Hyaluronan Oligosaccharides Improve Rosacea-Like Phenotype through Anti-Inflammatory and Epidermal Barrier-Improving Effects, Annals of Dermatology 2020
An essential fatty acid your sebum runs short on if you're acne-prone, and topping it up topically literally shrinks clogged pores. Also rebuilds the lipid mortar between skin cells. Found concentrated in safflower, hemp, and rosehip oils.
Lin TK, Zhong L, Santiago JL. Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils. Int J Mol Sci. 2017;19(1):70. — reviews linoleic-acid-rich oils in barrier repair.
Liu M et al., Topical application of a linoleic acid-ceramide containing moisturizer exhibit therapeutic and preventive benefits for psoriasis vulgaris: a randomized controlled trial, Dermatol Ther 2015;28(6):373-82 — RCT linoleic-acid/ceramide cream improved barrier
Letawe C, Boone M, Pierard GE. Digital image analysis of the effect of topically applied linoleic acid on acne microcomedones. Clin Exp Dermatol. 1998;23(2):56-58.
+−3 more ingredients
A staple in Hanbang (traditional Korean medicine) skincare. It's packed with antioxidants and ginsenosides that help firm the skin, boost circulation, and defend against environmental aging.
Jung SW et al., Protective Effects of Korean Red Ginseng Against Oxidative Stress-Induced Damage in Human Hair, Annals of Dermatology 2025
Kim H et al., The Beneficial Effect of Korean Red Ginseng Extract on Atopic Dermatitis Patients: An 8 Weeks Open, Noncomparative Clinical Study, Annals of Dermatology 2018
Park HM et al., A single-center, randomized, double-blind, placebo-controlled study on the efficacy and safety of enzyme-treated red ginseng powder complex (BG11001) for antiwrinkle and proelasticity in individuals with healthy skin, Journal of Ginseng Research 2016
Pro-vitamin B5. Deeply hydrates and helps repair the skin barrier, calming dry or compromised skin.
Gao Y et al., Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment, Journal of Cosmetic Dermatology 2025;24(7):e70223 — double-blind RCT (n=60): panthenol mask decreased erythema, enhanced hydration, repaired barrier vs saline
Cho YS et al., Use of Dexpanthenol for Atopic Dermatitis-Benefits and Recommendations Based on Current Evidence, Journal of Clinical Medicine 2022;11(14):3943 — Korean-authored review; dexpanthenol improves barrier and reduces severity in mild-to-moderate AD
Heise R et al., Accelerated wound healing with a dexpanthenol-containing ointment after fractional ablative CO2 laser resurfacing of photo-damaged skin in a randomized prospective clinical trial, Cutaneous and Ocular Toxicology 2019;38(3):274-278 — RCT: dexpanthenol significantly faster wound closure vs petroleum jelly post-laser
Goes into your pores and dissolves the oil and dead skin clogging them. Best for blackheads, whiteheads, and oily, acne-prone skin.
Liu Y et al., Clinical Efficacy of a Salicylic Acid-Containing Gel on Acne Management and Skin Barrier Function: A 21-Day Prospective Study, Journal of Cosmetic Dermatology 2025;24(7):e70353 — salicylic acid gel reduced acne lesions, regulated sebum, improved hydration and barrier function
Ye R et al., 2% supramolecular salicylic acid hydrogel vs. adapalene gel in mild to moderate acne vulgaris: multicenter, randomized, evaluator-blind, parallel-controlled trial, Journal of Cosmetic Dermatology 2024;23(6):2125-2134 — 2% SSA hydrogel was equally effective as adapalene gel for mild-to-moderate acne
Brumley C et al. Allergic contact dermatitis to salicylic acid: A case series of relevant sensitization. Contact Dermatitis. 2024;91(2):133-138. doi:10.1111/cod.14573 — Case series of 489 patch-tested patients (2020-2024): 21 positive reactions to salicylic acid. Documents that ACD to SA is likely underreported; testing at 5% concentration feasible.
Sources: 10 clinical journals and regulatory databases across the US, EU, Korea, Japan, and China. Every entry points to a specific document. See methodology for the full list and what each outcome label means.
Layering conflicts
Ingredients in this product that can react with common actives. Avoid stacking unless noted.
- Retinolhigh
Retinol + salicylic acid can over-exfoliate and damage the barrier. Alternate nights.
- Tretinoinhigh
Tretinoin + salicylic acid — major irritation risk. Strict separation required.
- Glycolic Acidmedium
AHA + BHA stacking risks over-exfoliation. Use a pre-formulated AHA/BHA product or alternate days.
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Not medical advice. GlowPal is educational. Patch-test new products and talk to a qualified healthcare professional before changing your routine, especially if you're pregnant, nursing, or have a diagnosed skin condition. See our terms.