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Shop Skin1004 Madagascar Centella Ampoule
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Skin1004

Madagascar Centella Ampoule

~$13.61· 3.38 fl oz
AcneDrynessRedness

What it's good for

Key actives from our research database. Click any to read the full evidence dossier.

  • Centella AsiaticaModerate evidenceFull dossier ↗

    Also called "cica," it calms redness, repairs the skin barrier, and speeds up recovery. The go-to for irritated or reactive skin.

    Good for: Anti-inflammatory, Barrier repair

  • MadecassosideModerate evidenceFull dossier ↗

    A purified compound from the cica (centella) plant, laser-focused on calming inflammation and speeding up how fast skin recovers.

    Good for: Anti-inflammatory, Barrier repair

Evidence behind the ingredients

Real citations from our research database, one per tracked active in this product. Click any ingredient name to read its full evidence dossier.

Centella AsiaticaModerate evidence6 citations

Also called "cica," it calms redness, repairs the skin barrier, and speeds up recovery. The go-to for irritated or reactive skin.

Hur N et al., A Randomized, Double-Blind, Placebo-Controlled Trial Assessing the Effects of Oral Centella asiatica Extract on Skin Aging-Related Parameters in Middle-Aged Korean Women, Nutrients 2026

2026Positive (efficacy)PMID:42196964View source ↗

Borowicz KK et al., Geroprotective Potential of Centella asiatica: Modulation of Cellular Aging, Nutrients 2026

2026Mechanism onlyPMID:42280293View source ↗

Witkowska K et al., Topical Application of Centella asiatica in Wound Healing: Recent Insights into Mechanisms and Clinical Efficacy, Pharmaceutics 2024;16(10):1252 — modern hydrogel and nanostructured Centella delivery systems accelerate wound healing across wound types

2024Meta-analysis (positive)PMID:39458583View source ↗
MadecassosideModerate evidence6 citations

A purified compound from the cica (centella) plant, laser-focused on calming inflammation and speeding up how fast skin recovers.

Liu L et al., Madecassoside Attenuated UVB Irradiation-Induced Skin Ferroptosis by Targeting POR, Phytomedicine 2026

2026Mechanism onlyPMID:41421280View source ↗

Bandopadhyay S et al., Therapeutic properties and pharmacological activities of asiaticoside and madecassoside: A review, Journal of Cellular and Molecular Medicine 2023;27(5):593-608 — comprehensive review of wound-healing, anti-inflammatory and regenerative activity

2023Meta-analysis (positive)PMID:36756687View source ↗

Park KS, Pharmacological Effects of Centella asiatica on Skin Diseases: Evidence and Possible Mechanisms, Evidence-Based Complementary and Alternative Medicine 2021;2021:5462633 — KR-authored review of triterpenes including madecassoside

2021Meta-analysis (positive)PMID:34845411View source ↗

Sources: 10 clinical journals and regulatory databases across the US, EU, Korea, Japan, and China. Every entry points to a specific document. See methodology for the full list and what each outcome label means.

Full ingredient list

Everything on the package label, not just the tracked actives above.

Fragrance freeDrying alcohol freeSulfates freeParabens freeSilicones free
+Show all 7 ingredients

Listed in the order printed on the package. By regulation, ingredients at 1% or higher are listed in descending order by concentration, so the first entry is the largest part of the formula.

  1. Water
  2. Glycerin
  3. Butylene Glycol
  4. Centella Asiatica Extract
  5. 1,2-Hexanediol
  6. Cellulose Gum
  7. Ethylhexylglycerin

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