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Shop Olay Regenerist Micro-Sculpting Cream
Moisturizer
Olay

Regenerist Micro-Sculpting Cream

~$28· 1.7 oz
Fine lines & firmnessDrynessRadiance

What it's good for

Key actives from our research database. Click any to read the full evidence dossier.

  • NiacinamideStrong evidenceFull dossier ↗

    A multitasker that calms redness, evens out skin tone, and helps oily skin balance out. One of the safest do-a-little-of-everything ingredients.

    Good for: Brightening, Barrier repair, Anti-inflammatory

  • GlycerinModerate evidenceFull dossier ↗

    A workhorse hydrator that pulls water into your skin. In nearly every good moisturizer for a reason.

    Good for: Hydrating

  • Hyaluronic AcidStrong evidenceFull dossier ↗

    A pure hydrator that holds water in your skin. Makes skin look plumper and smoother almost immediately.

    Good for: Hydrating

Evidence behind the ingredients

Real citations from our research database, one per tracked active in this product. Click any ingredient name to read its full evidence dossier.

NiacinamideStrong evidence10 citations

A multitasker that calms redness, evens out skin tone, and helps oily skin balance out. One of the safest do-a-little-of-everything ingredients.

Moro F et al., Skin Cancer Prevention and Antiaging: Role of Nicotinamide, International Journal of Molecular Sciences 2026

2026Mechanism onlyPMID:42278444View source ↗

Passeron T et al., An Investigator-Blinded, Randomized Trial of a Broad-Spectrum Sunscreen Containing Sclareolide and Niacinamide, Dermatology and Therapy (Heidelberg) 2026

2026Positive (efficacy)PMID:41240206View source ↗

Vergilio MM et al., Topical Formulation with Niacinamide Combined with 5 MHz Ultrasound for Improving Skin Ageing, Current Medicinal Chemistry 2025

2025Positive (efficacy)PMID:39171587View source ↗
GlycerinModerate evidence6 citations

A workhorse hydrator that pulls water into your skin. In nearly every good moisturizer for a reason.

Danby SG et al., Different types of emollient cream exhibit diverse physiological effects on the skin barrier in adults with atopic dermatitis, Clinical and Experimental Dermatology 2022;47(6):1154-1164 — glycerol+urea emollient delivered superior barrier-strengthening and irritant protection

2022Positive (efficacy)PMID:35167133View source ↗

Youssef R et al., Glycerol 85% efficacy on atopic skin and its microbiome: a randomized controlled trial, Journal of Dermatological Treatment 2021;32(7):730-736 — topical glycerol 85% RCT on atopic skin

2021Positive (efficacy)PMID:31869257View source ↗

Evans NJ et al., Human axillary skin condition is improved following incorporation of glycerol into the stratum corneum from an antiperspirant formulation, Archives of Dermatological Research 2017;309(9):739-748 — 4% glycerol penetrated axillary SC, reduced irritation, improved hydration

2017Positive (efficacy)PMID:28889318View source ↗
Hyaluronic AcidStrong evidence7 citations

A pure hydrator that holds water in your skin. Makes skin look plumper and smoother almost immediately.

Karabat MU, Tuncer MC. Effects of hyaluronic acid on skin at the cellular level: a systematic review. Rev Assoc Med Bras. 2025;71(8):e20250208. — Systematic review of 45 studies found low-molecular-weight HA stimulates keratinocyte proliferation and migration while high-molecular-weight HA drives skin hydration, supporting topical HA as an effective skin-hydrating and barrier-supporting ingredient.

2025Meta-analysis (positive)PMID:40990743View source ↗

Bravo B et al., Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence, Dermatology and Therapy 2022;12(12):2657-2680 — HA-based cosmeceuticals reliably improve hydration and signs of skin aging

2022Meta-analysis (positive)PMID:36200921View source ↗

Lee SG et al., Hyaluronan Oligosaccharides Improve Rosacea-Like Phenotype through Anti-Inflammatory and Epidermal Barrier-Improving Effects, Annals of Dermatology 2020

2020Mechanism onlyPMID:33911737View source ↗

Sources: 10 clinical journals and regulatory databases across the US, EU, Korea, Japan, and China. Every entry points to a specific document. See methodology for the full list and what each outcome label means.

Full ingredient list

Everything on the package label, not just the tracked actives above.

Drying alcohol freeSulfates free
  • Contains fragrance: Benzyl Alcohol, FragranceWorth knowing if you have sensitive or reactive skin.
  • Contains parabens: Ethylparaben, Methylparaben, PropylparabenNo irritancy evidence. CIR rates this safe as used; some shoppers avoid it by preference.
  • Contains silicones: Dimethicone, DimethiconolNo irritancy evidence. CIR rates this safe as used; some shoppers avoid it by preference.
+Show all 42 ingredients

Listed in the order printed on the package. By regulation, ingredients at 1% or higher are listed in descending order by concentration, so the first entry is the largest part of the formula.

  1. Water
  2. Glycerin
  3. Isohexadecane
  4. Niacinamide (Vitamin B3)
  5. Isopropyl Isostearate
  6. Aluminum Starch Octenylsuccinate
  7. Nylon-12
  8. Dimethicone
  9. Panthenol (Pro-Vitamin B5)
  10. Tocopheryl Acetate (Vitamin E)
  11. Sodium Hyaluronate
  12. Palmitoyl Pentapeptide-4 (Amino-Peptide)
  13. Camellia Sinensis Leaf Extract (Green Tea)
  14. Aloe Barbadensis Leaf Juice (Aloe Vera)
  15. Allantoin
  16. Stearyl Alcohol
  17. Polyethylene
  18. Cetyl Alcohol
  19. Sodium Acrylates Copolymer
  20. Behenyl Alcohol
  21. Benzyl Alcohol
  22. Acrylamide/​Sodium Acryloyldimethyltaurate Copolymer
  23. Dimethiconol
  24. Sodium Peg-7 Olive Oil Carboxylate
  25. Peucedanum Graveolens (Dill) Extract
  26. Peg-100 Stearate
  27. Stearic Acid
  28. Disodium Edta
  29. Cetearyl Glucoside
  30. Cetearyl Alcohol
  31. Citric Acid
  32. C12-13 Pareth-3
  33. Laureth-7
  34. C13-14 Isoparaffin
  35. Sodium Hydroxide
  36. Caprylic/​Capric Triglyceride
  37. Ethylparaben
  38. Methylparaben
  39. Propylparaben
  40. Fragrance
  41. Titanium Dioxide
  42. Mica

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