No.9 NAD+ Retinol Volumetox Eye Cream
- Routine step
- Treatment
- When
- Morning and evening
- Pairs well with
- Tretinoin, Adapalene, Retinaldehyde, Niacinamide
- Use with care
- 6 layering conflicts, listed below
Apply a thin layer to the areas you are treating, after serums and before moisturizer. Follow the label on frequency.
This product contains an active that can irritate at first. Patch test on the inner forearm for 24 hours and start two or three times a week.
Ingredient research in this formula
These are ingredient-level research links, not evidence that this exact product has been clinically tested.
Speeds up how fast your skin renews itself so old, dull cells shed faster and fresher skin shows through. Builds collagen over time, smoothing fine lines.
Good for: Anti-aging
The ultimate "cell recharger." It boosts your skin's cellular energy to speed up repair and protect against aging at the DNA level. It's the new high-tech standard for longevity skincare.
Good for: Anti-aging, Barrier repair
Evidence behind the ingredients
Real citations from our research database, one per tracked active in this product. Click any ingredient name to read its full evidence dossier.
Speeds up how fast your skin renews itself so old, dull cells shed faster and fresher skin shows through. Builds collagen over time, smoothing fine lines.
SCCS Revision of the Scientific Opinion on Vitamin A (Retinol, Retinyl Acetate, Retinyl Palmitate), SCCS/1639/21, final version adopted 24-25 October 2022
Chien AL et al. Biomarkers of Tretinoin Precursors and Tretinoin Efficacy in Patients With Moderate to Severe Facial Photodamage: A Randomized Clinical Trial. JAMA Dermatology. 2022;158(8):892-900. doi:10.1001/jamadermatol.2022.1891: RCT comparing topical retinol precursors vs tretinoin for photoaging; both showed equivalent wrinkle reduction at week 24 with retinol formulation causing 6x less erythema than tretinoin.
MFDS Approved Functional Cosmetic Active: Retinol (anti-wrinkle). Korean Ministry of Food and Drug Safety, Cosmetic Functional Active Ingredient List: listed alongside Adenosine, Retinyl Palmitate, and Polyethoxylated Retinamide in the Korean Functional Cosmetics Codex anti-wrinkle category
The ultimate "cell recharger." It boosts your skin's cellular energy to speed up repair and protect against aging at the DNA level. It's the new high-tech standard for longevity skincare.
Ministrini S, Liberale L, Erle HE, Percoco G, Tfayli A, Assi A, Kapitonov I, Greiner I, Camici GG, A Liposomal Formulation Enhances the Anti-Senescence Properties of Nicotinamide Adenine-Dinucleotide (NAD+) in Endothelial Cells and Keratinocytes, Current Issues in Molecular Biology 2025: in-vitro: liposomal NAD+ reduced senescent cells in human keratinocytes and endothelial cells and increased skin penetration about 30% vs free NAD+ (cell-based mechanism)
Kang S, Park J, Cheng Z, Ye S, Jun SH, Kang NG, Novel Approach to Skin Anti-Aging: Boosting Pharmacological Effects of Exogenous Nicotinamide Adenine Dinucleotide (NAD+) by Synergistic Inhibition of CD38 Expression, Cells 2024: in-vitro: exogenous NAD+ on human fibroblasts protected against UV-induced and intrinsic aging via sirtuin/autophagy pathways; effect amplified by CD38 inhibition (cell-based mechanism)
Sources: 10 clinical journals and regulatory databases across the US, EU, Korea, Japan, and China. Every entry points to a specific document. See methodology for the full list and what each outcome label means.
Layering conflicts
Ingredients in this product that can react with common actives. Avoid stacking unless noted.
- Salicylic Acidhigh
Retinol + salicylic acid can over-exfoliate and damage the barrier. Alternate nights.
- Glycolic Acidhigh
Retinol + glycolic acid is a classic barrier-buster. Use on different nights.
- Lactic Acidmedium
Retinol + lactic acid is gentler than glycolic but still alternate nights to be safe.
- Mandelic Acidmedium
Retinol + mandelic acid: alternate nights to preserve barrier integrity.
- Benzoyl Peroxidemedium
Benzoyl peroxide can break down retinol. Use one in the morning and the other at night, or pick a stabilized formula made to combine them.
- Vitamin Clow
Vitamin C and retinol work best at different pH levels. Use vitamin C in the morning and retinol at night.
Similar comparisons
Not medical advice. GlowPal is educational. Patch-test new products and talk to a qualified healthcare professional before changing your routine, especially if you're pregnant, nursing, or have a diagnosed skin condition. See our terms.