Shop numbuzin No.3 Toner Pads (70 Pads)
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No.3 Toner Pads (70 Pads)

~$16· 70 Pads
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Evidence behind the ingredients

Real citations from our research database — one per tracked active in this product. Click any ingredient name to read its full evidence dossier.

NiacinamideStrong evidence11 citations

A multitasker that calms redness, evens out skin tone, and helps oily skin balance out. One of the safest do-a-little-of-everything ingredients.

Moro F et al., Skin Cancer Prevention and Antiaging: Role of Nicotinamide, International Journal of Molecular Sciences 2026

2026Mechanism onlyPMID:42278444View source ↗

Passeron T et al., An Investigator-Blinded, Randomized Trial of a Broad-Spectrum Sunscreen Containing Sclareolide and Niacinamide, Dermatology and Therapy (Heidelberg) 2026

2026Positive — efficacyPMID:41240206View source ↗

Vergilio MM et al., Topical Formulation with Niacinamide Combined with 5 MHz Ultrasound for Improving Skin Ageing, Current Medicinal Chemistry 2025

2025Positive — efficacyPMID:39171587View source ↗
Bifida Ferment LysateModerate evidence5 citations

A probiotic-based ingredient that strengthens your skin's defenses against irritation and environmental stress.

Zhu X et al., Protective effect of Bifidobacterium animalis CGMCC25262 on HaCaT keratinocytes, International Microbiology 2024;27(5):1417-1428 — B. animalis lysate upregulated HAS-2, AQP3, FLG and reduced RANTES under TNF-α/IFN-γ

2024Mechanism onlyPMID:38278974View source ↗

Korean authors et al., Selection of microbiome extracts using 3D human skin equivalents and clinical evaluation of an emulsion for skin wrinkle improvement, Journal of the Society of Cosmetic Scientists of Korea 2023;49(1):47-58 — 21-woman 2-week clinical trial: 5% (v/v) Bifidobacterium bifidum fermented filtrate emulsion reduced periocular wrinkles 5.6% more than placebo

2023Positive — efficacyKCI:ART002947739View source ↗

Wang R et al., The pivotal role of Bifida Ferment Lysate on reinforcing the skin barrier function and maintaining homeostasis of skin defenses in vitro, Journal of Cosmetic Dermatology 2023;22(12):3427-3435 — BFL upregulated barrier and antioxidant genes; reduced inflammatory signaling

2023Mechanism onlyPMID:37218728View source ↗
AdenosineModerate evidence7 citations

A Korean-approved anti-wrinkle ingredient that encourages collagen production for a smoother, firmer look.

Nguyen NH et al., Translational Evaluation of a Disodium Adenosine Monophosphate (AMP2Na)-Based Topical Formulation for Physiology-Aligned Skin Rejuvenation, International Journal of Molecular Sciences 2026

2026Mechanism onlyPMID:42278371View source ↗

MFDS Approved Functional Cosmetic Active — Adenosine (anti-wrinkle). Korean Ministry of Food and Drug Safety, Cosmetic Functional Active Ingredient List

2020Regulatory approvalMFDS:Adenosine-AntiWrinkleView source ↗

Jang M et al., Dissolving microneedle with high molecular weight hyaluronic acid to improve skin wrinkles, dermal density and elasticity, International Journal of Cosmetic Science 2020;42(3):302-309 — Korean comparison: HMW HA + adenosine outperformed LMW HA across wrinkle and elasticity parameters

2020Positive — efficacyPMID:32421218View source ↗
+2 more ingredients
Hyaluronic AcidStrong evidence7 citations

A pure hydrator that holds water in your skin. Makes skin look plumper and smoother almost immediately.

Bravo B et al., Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence, Dermatology and Therapy 2022;12(12):2657-2680 — HA-based cosmeceuticals reliably improve hydration and signs of skin aging

2022Meta-analysis — positivePMID:36200921View source ↗

Lee SG et al., Hyaluronan Oligosaccharides Improve Rosacea-Like Phenotype through Anti-Inflammatory and Epidermal Barrier-Improving Effects, Annals of Dermatology 2020

2020Mechanism onlyPMID:33911737View source ↗

An JH et al., Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin, Annals of Dermatology 2019;31(3):263-271 — cross-linked HA microneedle patches improved wrinkles on Korean skin with minimal discomfort

2019Positive — efficacyPMID:33911590View source ↗
Lactobacillus FermentAnecdotal evidence4 citations

A "postbiotic" (dead probiotic bits) that talks to your skin microbiome without adding live bugs. Patches up a leaky barrier and is friendly even on very reactive skin.

Algieri F, Pimazzoni S et al. (Italy), Postbiotic derived from Lacticaseibacillus paracasei CNCM I-5220 as a novel approach to improve ageing-induced skin damage, Scientific Reports 2026 — 6-week topical postbiotic application reduced roughness and increased hydration, elasticity, and echogenicity vs placebo; boosted hyaluronic acid in keratinocytes and pro-collagen in fibroblasts

2026Positive — efficacyPMID:42168426View source ↗

Flores Rodriguez JC et al. (Mexico/Colombia/Costa Rica), Postbiotics in Dermatology: A Literature Review of Emerging Topical Therapies for Acne, Rosacea, and Eczema, Cureus 2026;18(3) — review of 16 studies: postbiotics improved SCORAD and barrier function in atopic dermatitis; reduced inflammatory acne lesions 50-70% and suppressed sebum 42-72%

2026Meta-analysis — positivePMID:42005241View source ↗

Effects of a lotion containing probiotic ferment lysate as the main functional ingredient on enhancing skin barrier: a randomized, self-control study, Scientific Reports 2023

2023Positive — efficacyPMID:37803101View source ↗

Sources: PubMed · KCI · J-Stage · CNKI · Wanfang · SFD · MFDS · Cochrane · SCCS · CIR. Every entry points to a specific document. See methodology for what each outcome label means.

Layering conflicts

Ingredients in this product that can react with common actives. Avoid stacking unless noted.

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