Time Revolution Night Repair Ampoule 5th Gen 50ml
What it's good for
Key actives from our research database. Click any to read the full evidence dossier.
A probiotic-based ingredient that strengthens your skin's defenses against irritation and environmental stress.
Good for: Barrier repair, Anti-inflammatory
A "postbiotic" (dead probiotic bits) that talks to your skin microbiome without adding live bugs. Patches up a leaky barrier and is friendly even on very reactive skin.
Good for: Barrier repair, Hydrating
A multitasker that calms redness, evens out skin tone, and helps oily skin balance out. One of the safest do-a-little-of-everything ingredients.
Good for: Brightening, Barrier repair, Anti-inflammatory
A lightweight oil that mimics what your skin already makes. Softens and seals in hydration without feeling greasy.
Good for: Barrier repair, Hydrating
Pro-vitamin B5. Deeply hydrates and helps repair the skin barrier, calming dry or compromised skin.
Good for: Hydrating, Barrier repair
A Korean-approved anti-wrinkle ingredient that encourages collagen production for a smoother, firmer look.
Good for: Anti-aging
Evidence behind the ingredients
Real citations from our research database, one per tracked active in this product. Click any ingredient name to read its full evidence dossier.
A probiotic-based ingredient that strengthens your skin's defenses against irritation and environmental stress.
Zhu X et al., Protective effect of Bifidobacterium animalis CGMCC25262 on HaCaT keratinocytes, International Microbiology 2024;27(5):1417-1428 — B. animalis lysate upregulated HAS-2, AQP3, FLG and reduced RANTES under TNF-α/IFN-γ
Wang Y et al., Short-term skin reactions and changes in stratum corneum following different ways of facial sheet mask usage, Journal of Tissue Viability 2024;33(4):831-839 — evaluated topical bifida ferment lysate masks on skin barrier measures
Wang R et al., The pivotal role of Bifida Ferment Lysate on reinforcing the skin barrier function and maintaining homeostasis of skin defenses in vitro, Journal of Cosmetic Dermatology 2023;22(12):3427-3435 — BFL upregulated barrier and antioxidant genes; reduced inflammatory signaling
A "postbiotic" (dead probiotic bits) that talks to your skin microbiome without adding live bugs. Patches up a leaky barrier and is friendly even on very reactive skin.
Algieri F, Pimazzoni S et al. (Italy), Postbiotic derived from Lacticaseibacillus paracasei CNCM I-5220 as a novel approach to improve ageing-induced skin damage, Scientific Reports 2026 — 6-week topical postbiotic application reduced roughness and increased hydration, elasticity, and echogenicity vs placebo; boosted hyaluronic acid in keratinocytes and pro-collagen in fibroblasts
Flores Rodriguez JC et al. (Mexico/Colombia/Costa Rica), Postbiotics in Dermatology: A Literature Review of Emerging Topical Therapies for Acne, Rosacea, and Eczema, Cureus 2026;18(3) — review of 16 studies: postbiotics improved SCORAD and barrier function in atopic dermatitis; reduced inflammatory acne lesions 50-70% and suppressed sebum 42-72%
Flint E et al., Topical Probiotics Reduce Atopic Dermatitis Severity: A Systematic Review and Meta-Analysis, Cureus 2024;16(9):e70001 — SR/MA of topical Lactobacillus probiotics for atopic dermatitis
A multitasker that calms redness, evens out skin tone, and helps oily skin balance out. One of the safest do-a-little-of-everything ingredients.
Moro F et al., Skin Cancer Prevention and Antiaging: Role of Nicotinamide, International Journal of Molecular Sciences 2026
Passeron T et al., An Investigator-Blinded, Randomized Trial of a Broad-Spectrum Sunscreen Containing Sclareolide and Niacinamide, Dermatology and Therapy (Heidelberg) 2026
Vergilio MM et al., Topical Formulation with Niacinamide Combined with 5 MHz Ultrasound for Improving Skin Ageing, Current Medicinal Chemistry 2025
+−3 more ingredients
A lightweight oil that mimics what your skin already makes. Softens and seals in hydration without feeling greasy.
Wolosik K et al., Squalane as a Promising Agent Protecting UV-Induced Inhibition of Collagen Biosynthesis and Wound Healing in Human Dermal Fibroblast, Molecules 2025;30(9):1964 — low-dose squalane (0.005-0.015%) restored collagen biosynthesis and wound healing in UVA-exposed human dermal fibroblasts
Morgan AB et al., Explicating the multifunctional roles of tocotrienol and squalene in promoting skin health, Skin Health and Disease 2024;4(5):e448 — squalene/squalane promotes skin health via antioxidant, hydrating, emollient, anti-inflammatory mechanisms
Fiume M et al., Safety Assessment of Squalane and Squalene as Used in Cosmetics, International Journal of Toxicology 2023;42(3_suppl):107S-109S — CIR expert-panel assessment concluding squalane is safe as a cosmetic ingredient
Pro-vitamin B5. Deeply hydrates and helps repair the skin barrier, calming dry or compromised skin.
Gao Y et al., Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment, Journal of Cosmetic Dermatology 2025;24(7):e70223 — double-blind RCT (n=60): panthenol mask decreased erythema, enhanced hydration, repaired barrier vs saline
Cho YS et al., Use of Dexpanthenol for Atopic Dermatitis-Benefits and Recommendations Based on Current Evidence, Journal of Clinical Medicine 2022;11(14):3943 — Korean-authored review; dexpanthenol improves barrier and reduces severity in mild-to-moderate AD
Heise R et al., Accelerated wound healing with a dexpanthenol-containing ointment after fractional ablative CO2 laser resurfacing of photo-damaged skin in a randomized prospective clinical trial, Cutaneous and Ocular Toxicology 2019;38(3):274-278 — RCT: dexpanthenol significantly faster wound closure vs petroleum jelly post-laser
A Korean-approved anti-wrinkle ingredient that encourages collagen production for a smoother, firmer look.
Yang HJ et al., Two-phase delivery using a horse oil and adenosine-loaded dissolving microneedle patch for skin barrier restoration, moisturization, and wrinkle improvement, Journal of Cosmetic Dermatology 2019;18(3):936-943 — Korean clinical study (n=20): adenosine microneedle patches improved elasticity, hydration, dermal density, wrinkles
Kang G et al., Adenosine-loaded dissolving microneedle patches to improve skin wrinkles, dermal density, elasticity and hydration, International Journal of Cosmetic Science 2018;40(2):199-206 — Korean-authored; adenosine microneedle patches matched or exceeded adenosine cream for multiple endpoints
Kim MY et al., Effect of adenosine on melanogenesis in B16 cells and zebrafish, Annals of Dermatology 2014;26(2):209-13 — adenosine suppresses pigmentation via negative regulation of tyrosinase in cellular and zebrafish models
Sources: 10 clinical journals and regulatory databases across the US, EU, Korea, Japan, and China. Every entry points to a specific document. See methodology for the full list and what each outcome label means.
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