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Shop medicube Collagen Jelly Cream
Moisturizer
medicube

Collagen Jelly Cream

~$19.98· Standard Size

What it's good for

Key actives from our research database. Click any to read the full evidence dossier.

  • NiacinamideStrong evidenceFull dossier ↗

    A multitasker that calms redness, evens out skin tone, and helps oily skin balance out. One of the safest do-a-little-of-everything ingredients.

    Good for: Brightening, Barrier repair, Anti-inflammatory

  • SqualaneAnecdotal evidenceFull dossier ↗

    A lightweight oil that mimics what your skin already makes. Softens and seals in hydration without feeling greasy.

    Good for: Barrier repair, Hydrating

  • AdenosineModerate evidenceFull dossier ↗

    A Korean-approved anti-wrinkle ingredient that encourages collagen production for a smoother, firmer look.

    Good for: Anti-aging

  • GlycerinModerate evidenceFull dossier ↗

    A workhorse hydrator that pulls water into your skin. In nearly every good moisturizer for a reason.

    Good for: Hydrating

  • Vitamin EModerate evidenceFull dossier ↗

    A workhorse antioxidant that defends your skin from daily oxidative damage. Pairs especially well with vitamin C, and it's in nearly every good moisturizer for a reason.

    Good for: Antioxidant

  • Hydrolyzed CollagenModerate evidenceFull dossier ↗

    The protein your skin loses with age, broken down small enough to absorb. Multiple meta-analyses of RCTs show measurable wins in wrinkles, elasticity, and hydration after ~12 weeks. Most evidence is oral, but topical helps surface hydration too.

    Good for: Anti-aging, Hydrating

  • CeramidesStrong evidenceFull dossier ↗

    Refills the natural barrier between your skin cells. Locks moisture in, keeps irritants out, calms dry or damaged skin.

    Good for: Barrier repair

Evidence behind the ingredients

Real citations from our research database, one per tracked active in this product. Click any ingredient name to read its full evidence dossier.

NiacinamideStrong evidence10 citations

A multitasker that calms redness, evens out skin tone, and helps oily skin balance out. One of the safest do-a-little-of-everything ingredients.

Moro F et al., Skin Cancer Prevention and Antiaging: Role of Nicotinamide, International Journal of Molecular Sciences 2026

2026Mechanism onlyPMID:42278444View source ↗

Passeron T et al., An Investigator-Blinded, Randomized Trial of a Broad-Spectrum Sunscreen Containing Sclareolide and Niacinamide, Dermatology and Therapy (Heidelberg) 2026

2026Positive (efficacy)PMID:41240206View source ↗

Vergilio MM et al., Topical Formulation with Niacinamide Combined with 5 MHz Ultrasound for Improving Skin Ageing, Current Medicinal Chemistry 2025

2025Positive (efficacy)PMID:39171587View source ↗
SqualaneAnecdotal evidence5 citations

A lightweight oil that mimics what your skin already makes. Softens and seals in hydration without feeling greasy.

Wolosik K et al., Squalane as a Promising Agent Protecting UV-Induced Inhibition of Collagen Biosynthesis and Wound Healing in Human Dermal Fibroblast, Molecules 2025;30(9):1964 — low-dose squalane (0.005-0.015%) restored collagen biosynthesis and wound healing in UVA-exposed human dermal fibroblasts

2025Mechanism onlyPMID:40363772View source ↗

Morgan AB et al., Explicating the multifunctional roles of tocotrienol and squalene in promoting skin health, Skin Health and Disease 2024;4(5):e448 — squalene/squalane promotes skin health via antioxidant, hydrating, emollient, anti-inflammatory mechanisms

2024Mechanism onlyPMID:39355739View source ↗

Fiume M et al., Safety Assessment of Squalane and Squalene as Used in Cosmetics, International Journal of Toxicology 2023;42(3_suppl):107S-109S — CIR expert-panel assessment concluding squalane is safe as a cosmetic ingredient

2023Safety assessmentPMID:37752766View source ↗
AdenosineModerate evidence6 citations

A Korean-approved anti-wrinkle ingredient that encourages collagen production for a smoother, firmer look.

Yang HJ et al., Two-phase delivery using a horse oil and adenosine-loaded dissolving microneedle patch for skin barrier restoration, moisturization, and wrinkle improvement, Journal of Cosmetic Dermatology 2019;18(3):936-943 — Korean clinical study (n=20): adenosine microneedle patches improved elasticity, hydration, dermal density, wrinkles

2019Positive (efficacy)PMID:30160014View source ↗

Kang G et al., Adenosine-loaded dissolving microneedle patches to improve skin wrinkles, dermal density, elasticity and hydration, International Journal of Cosmetic Science 2018;40(2):199-206 — Korean-authored; adenosine microneedle patches matched or exceeded adenosine cream for multiple endpoints

2018Positive (efficacy)PMID:29574973View source ↗

Kim MY et al., Effect of adenosine on melanogenesis in B16 cells and zebrafish, Annals of Dermatology 2014;26(2):209-13 — adenosine suppresses pigmentation via negative regulation of tyrosinase in cellular and zebrafish models

2014Mechanism onlyPMID:24882976View source ↗
+4 more ingredients
GlycerinModerate evidence6 citations

A workhorse hydrator that pulls water into your skin. In nearly every good moisturizer for a reason.

Danby SG et al., Different types of emollient cream exhibit diverse physiological effects on the skin barrier in adults with atopic dermatitis, Clinical and Experimental Dermatology 2022;47(6):1154-1164 — glycerol+urea emollient delivered superior barrier-strengthening and irritant protection

2022Positive (efficacy)PMID:35167133View source ↗

Youssef R et al., Glycerol 85% efficacy on atopic skin and its microbiome: a randomized controlled trial, Journal of Dermatological Treatment 2021;32(7):730-736 — topical glycerol 85% RCT on atopic skin

2021Positive (efficacy)PMID:31869257View source ↗

Evans NJ et al., Human axillary skin condition is improved following incorporation of glycerol into the stratum corneum from an antiperspirant formulation, Archives of Dermatological Research 2017;309(9):739-748 — 4% glycerol penetrated axillary SC, reduced irritation, improved hydration

2017Positive (efficacy)PMID:28889318View source ↗
Vitamin EModerate evidence6 citations

A workhorse antioxidant that defends your skin from daily oxidative damage. Pairs especially well with vitamin C, and it's in nearly every good moisturizer for a reason.

Neves JR et al., Efficacy of a topical serum containing L-ascorbic acid, neohesperidin, pycnogenol, tocopherol, and hyaluronic acid in relation to skin aging signs, Journal of Cosmetic Dermatology 2022;21(10):4462-4469 — tocopherol-containing antioxidant serum reduced pollution-induced damage and improved aging signs

2022Positive (efficacy)PMID:35150043View source ↗

Warshaw EM et al., Patch Testing With Tocopherol and Tocopherol Acetate: The North American Contact Dermatitis Group Experience, 2001 to 2016, Dermatitis 2021;32(5):308-318 — 15-year NACDG data: positive patch-test reactions to tocopherol rare given widespread cosmetic use

2021Safety assessmentPMID:34238818View source ↗

Lin FH et al., Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin, Journal of Investigative Dermatology 2005;125(4):826-832 — ferulic acid + vit C + vit E combo doubled photoprotection vs C+E alone (cross-listed; same paper cited for Ferulic Acid and Vit C)

2005Positive (efficacy)PMID:16185284View source ↗
Hydrolyzed CollagenModerate evidence7 citations

The protein your skin loses with age, broken down small enough to absorb. Multiple meta-analyses of RCTs show measurable wins in wrinkles, elasticity, and hydration after ~12 weeks. Most evidence is oral, but topical helps surface hydration too.

Reilly DM, Kynaston L, Naseem S, Proudman E, Laceby D. A Clinical Trial Shows Improvement in Skin Collagen, Hydration, Elasticity, Wrinkles, Scalp, and Hair Condition following 12-Week Oral Intake of a Supplement Containing Hydrolysed Collagen. Dermatology Research and Practice. 2024. — Randomized double-blind placebo-controlled trial; 12-week oral collagen supplement showed 44.6% decrease in collagen fragmentation, +13.8% hydration, +22.7% elasticity, -19.6% wrinkle index vs placebo.

2024Positive (efficacy)PMID:39021368View source ↗

Demir-Dora D, Ozsoy U, Yildirim Y, et al. The Efficacy and Safety of CollaSel Pro® Hydrolyzed Collagen Peptide Supplementation without Addons in Improving Skin Health in Adult Females: A Double Blind, Randomized, Placebo-Controlled Clinical Study. Journal of Clinical Medicine. 2024 Sep 11. — Double-blind RCT (n=112); significant improvements in skin elasticity (p=0.009), hydration (p<0.001), and roughness vs placebo.

2024Positive (efficacy)PMID:39336856View source ↗

Pu SY et al., Effects of Oral Collagen for Skin Anti-Aging: A Systematic Review and Meta-Analysis, Nutrients 2023;15(9):2080 — 26 RCTs / 1,721 patients: hydrolyzed collagen significantly improved skin hydration and elasticity vs placebo across multiple collagen sources

2023Meta-analysis (positive)PMID:37432180View source ↗
CeramidesStrong evidence7 citations

Refills the natural barrier between your skin cells. Locks moisture in, keeps irritants out, calms dry or damaged skin.

Andrew PV et al., Topical supplementation with physiological lipids rebalances the stratum corneum ceramide profile and strengthens skin barrier function in adults predisposed to atopic dermatitis, British Journal of Dermatology 2025;193(4):729-740 — physiological-lipid emulsion raised SC ceramide NP/AP and improved barrier function vs control

2025Positive (efficacy)PMID:40408261View source ↗

Nugroho WT, Sawitri, Astindari, Utomo B, Listiawan MY, Ervianti E, Astari L. The Efficacy of Moisturisers Containing Ceramide Compared with Other Moisturisers in the Management of Atopic Dermatitis: A Systematic Literature Review and Meta-Analysis. Indian J Dermatol. 2023;68(1):53-58. — Meta-analysis of 5 studies found ceramide-containing moisturisers produced significantly greater improvement in SCORAD compared with non-ceramide moisturisers in atopic dermatitis.

2023Meta-analysis (positive)PMID:37151263View source ↗

Shindo S et al., Effects of a moisturizer containing pseudo-ceramide and a eucalyptus extract on sweating function in adult atopic dermatitis: a double-blind, randomized, controlled left-right comparison clinical trial, Journal of Cosmetic Dermatology 2022;21(10):4503-4509 — pseudo-ceramide + eucalyptus moisturizer restored sweating function and barrier in AD adults

2022Positive (efficacy)PMID:35298858View source ↗

Sources: 10 clinical journals and regulatory databases across the US, EU, Korea, Japan, and China. Every entry points to a specific document. See methodology for the full list and what each outcome label means.

Full ingredient list

Everything on the package label, not just the tracked actives above.

Drying alcohol freeSulfates freeParabens freeSilicones free
  • Contains fragrance: Fragrance(Parfum)Worth knowing if you have sensitive or reactive skin.
+Show all 48 ingredients

Listed in the order printed on the package. By regulation, ingredients at 1% or higher are listed in descending order by concentration, so the first entry is the largest part of the formula.

  1. Water
  2. Propanediol
  3. Dipropylene Glycol
  4. Butylene Glycol
  5. Methylpropanediol
  6. Diethoxyethyl Succinate
  7. Ethoxydiglycol
  8. Ammonium Acryloyldimethyltaurate/​Beheneth-25 Methacrylate Crosspolymer
  9. Niacinamide
  10. Trehalose
  11. 1,2-Hexanediol
  12. Chlorella Vulgaris Extract
  13. Collagen
  14. Hydrolyzed Collagen
  15. Cynanchum Atratum Extract
  16. Althaea Rosea Flower Extract
  17. Soluble Collagen
  18. Allium Sativum (Garlic) Bulb Extract
  19. Avena Sativa (Oat) Kernel Extract
  20. Bertholletia Excelsa Seed Extract
  21. Brassica Oleracea Italica (Broccoli) Extract
  22. Camellia Sinensis Seed Extract
  23. Salmon Egg Extract
  24. Solanum Lycopersicum (Tomato) Fruit Extract
  25. Spinacia Oleracea (Spinach) Leaf Extract
  26. Vaccinium Angustifolium (Blueberry) Fruit Extract
  27. Wine Extract
  28. Polyglyceryl-10 Isostearate
  29. Tromethamine
  30. Glucose
  31. Polyglyceryl-10 Oleate
  32. Ethylhexylglycerin
  33. Fructooligosaccharides
  34. Fructose
  35. Adenosine
  36. Sodium Phytate
  37. Cyanocobalamin
  38. Tocopherol
  39. Pullulan
  40. Glycerin
  41. Hydroxypropyltrimonium Hyaluronate
  42. Squalane
  43. Soluble Proteoglycan
  44. Hydrolyzed Elastin
  45. Sodium Dna
  46. Carbomer
  47. Xanthan Gum
  48. Fragrance(Parfum)

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Not medical advice. GlowPal is educational. Patch-test new products and talk to a qualified healthcare professional before changing your routine, especially if you're pregnant, nursing, or have a diagnosed skin condition. See our terms.