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Shop Isntree Hyaluronic Acid Watery Sun Gel SPF 50+ PA++++
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Isntree

Hyaluronic Acid Watery Sun Gel SPF 50+ PA++++

~$22· 1.69 fl ozAM onlySPF 50chemical filter
AcneVisible poresDryness

What it's good for

Key actives from our research database. Click any to read the full evidence dossier.

  • OctisalateModerate evidenceFull dossier ↗

    A supporting UVB filter that improves both protection and formula feel. It is rarely the star of a sunscreen, but it helps the complete filter blend deliver the SPF printed on the bottle.

    Good for: Sun protection

  • HomosalateModerate evidenceFull dossier ↗

    A supporting UVB filter in many lightweight chemical sunscreens. It helps a formula reach its labeled SPF, but it needs UVA partners such as avobenzone for broad-spectrum coverage.

    Good for: Sun protection

  • BemotrizinolModerate evidenceFull dossier ↗

    A modern broad-spectrum filter that covers both UVA and UVB and stays stable in sunlight. It is one reason many Korean and European sunscreens can combine high protection with a lighter feel.

    Good for: Sun protection

  • BisoctrizoleModerate evidenceFull dossier ↗

    A modern broad-spectrum filter known as Tinosorb M. It adds stable UVA and UVB coverage; because it is particulate, some formulas may show a slight cast depending on filter size and the rest of the base.

    Good for: Sun protection

  • Polysilicone-15Moderate evidenceFull dossier ↗

    A polymeric UVB filter used to build lightweight, silky sunscreen textures. It supports SPF while its silicone backbone helps the formula spread into an even protective film.

    Good for: Sun protection

  • DHHBModerate evidenceFull dossier ↗

    A modern UVA filter common in Korean and European sunscreens. It fills the long-wave UVA gap that UVB-focused filters cannot cover and is valued for remaining stable during sun exposure.

    Good for: Sun protection

  • Hyaluronic AcidStrong evidenceFull dossier ↗

    A pure hydrator that holds water in your skin. Makes skin look plumper and smoother almost immediately.

    Good for: Hydrating

  • PanthenolModerate evidenceFull dossier ↗

    Pro-vitamin B5. Deeply hydrates and helps repair the skin barrier, calming dry or compromised skin.

    Good for: Hydrating, Barrier repair

  • AllantoinAnecdotal evidenceFull dossier ↗

    A gentle smoother and skin-soother. Reduces flakiness and helps the surface look more even.

    Good for: Anti-inflammatory, Hydrating

Evidence behind the ingredients

Real citations from our research database, one per tracked active in this product. Click any ingredient name to read its full evidence dossier.

OctisalateModerate evidence2 citations

A supporting UVB filter that improves both protection and formula feel. It is rarely the star of a sunscreen, but it helps the complete filter blend deliver the SPF printed on the bottle.

Matta MK et al. Effect of Sunscreen Application on Plasma Concentration of Sunscreen Active Ingredients: A Randomized Clinical Trial. JAMA. 2020;323(3):256-267 — maximal-use study measured systemic exposure to octisalate and five other sunscreen actives.

2020Mechanism onlyPMID:31961417View source ↗

Bens G. Sunscreens. Advances in Experimental Medicine and Biology. 2014;810:429-463 — review of organic and inorganic sunscreen filters, their spectral roles, formulation, and safety considerations.

2014Mechanism onlyPMID:25207381View source ↗
HomosalateModerate evidence3 citations

A supporting UVB filter in many lightweight chemical sunscreens. It helps a formula reach its labeled SPF, but it needs UVA partners such as avobenzone for broad-spectrum coverage.

Matta MK et al. Effect of Sunscreen Application on Plasma Concentration of Sunscreen Active Ingredients: A Randomized Clinical Trial. JAMA. 2020;323(3):256-267 — maximal-use study measured systemic exposure to homosalate and five other sunscreen actives.

2020Mechanism onlyPMID:31961417View source ↗

Bens G. Sunscreens. Advances in Experimental Medicine and Biology. 2014;810:429-463 — review of organic and inorganic sunscreen filters, their spectral roles, formulation, and safety considerations.

2014Mechanism onlyPMID:25207381View source ↗

Kim TH et al. Percutaneous absorption, disposition, and exposure assessment of homosalate, a UV filtering agent, in rats. Journal of Toxicology and Environmental Health A. 2014;77(4):202-213.

2014Mechanism onlyPMID:24555679View source ↗
BemotrizinolModerate evidence2 citations

A modern broad-spectrum filter that covers both UVA and UVB and stays stable in sunlight. It is one reason many Korean and European sunscreens can combine high protection with a lighter feel.

Serpone N. Sunscreens and their usefulness: have we made any progress in the last two decades? Photochemical & Photobiological Sciences. 2021;20(2):189-244 — review of sunscreen-filter photochemistry, spectral coverage, stability, and formulation.

2021Mechanism onlyPMID:33721254View source ↗

Medeiros TS et al. Bemotrizinol-Loaded Carnauba Wax-Based Nanostructured Lipid Carriers for Sunscreen: Optimization, Characterization, and In vitro Evaluation. AAPS PharmSciTech. 2020;21(8):288.

2020Mechanism onlyPMID:33073311View source ↗
+6 more ingredients
BisoctrizoleModerate evidence3 citations

A modern broad-spectrum filter known as Tinosorb M. It adds stable UVA and UVB coverage; because it is particulate, some formulas may show a slight cast depending on filter size and the rest of the base.

Serpone N. Sunscreens and their usefulness: have we made any progress in the last two decades? Photochemical & Photobiological Sciences. 2021;20(2):189-244 — review of sunscreen-filter photochemistry, spectral coverage, stability, and formulation.

2021Mechanism onlyPMID:33721254View source ↗

Liuti F, Borrego L. Contact dermatitis caused by Tinosorb M: the importance of patch testing with pure methylene bis-benzotriazolyl tetramethylbutylphenol. Contact Dermatitis. 2015;73(3):192-193.

2015Mechanism onlyPMID:25962512View source ↗

Herzog B et al. In vivo and in vitro assessment of UVA protection by sunscreen formulations containing either butyl methoxy dibenzoyl methane, methylene bis-benzotriazolyl tetramethylbutylphenol, or microfine ZnO. International Journal of Cosmetic Science. 2002;24(3):170-185.

2002Positive (efficacy)PMID:18498509View source ↗
Polysilicone-15Moderate evidence2 citations

A polymeric UVB filter used to build lightweight, silky sunscreen textures. It supports SPF while its silicone backbone helps the formula spread into an even protective film.

Serpone N. Sunscreens and their usefulness: have we made any progress in the last two decades? Photochemical & Photobiological Sciences. 2021;20(2):189-244 — review of sunscreen-filter photochemistry, spectral coverage, stability, and formulation.

2021Mechanism onlyPMID:33721254View source ↗

Bens G. Sunscreens. Advances in Experimental Medicine and Biology. 2014;810:429-463 — review of organic and inorganic sunscreen filters, their spectral roles, formulation, and safety considerations.

2014Mechanism onlyPMID:25207381View source ↗
DHHBModerate evidence2 citations

A modern UVA filter common in Korean and European sunscreens. It fills the long-wave UVA gap that UVB-focused filters cannot cover and is valued for remaining stable during sun exposure.

Ye F et al. Ultrafast excited-state energy dissipation pathway of diethylamino hydroxybenzoyl hexyl benzoate (DHHB) via the nanoparticles. Photochemical & Photobiological Sciences. 2023;22(9):2133-2142.

2023Mechanism onlyPMID:37195390View source ↗

Serpone N. Sunscreens and their usefulness: have we made any progress in the last two decades? Photochemical & Photobiological Sciences. 2021;20(2):189-244 — review of sunscreen-filter photochemistry, spectral coverage, stability, and formulation.

2021Mechanism onlyPMID:33721254View source ↗
Hyaluronic AcidStrong evidence7 citations

A pure hydrator that holds water in your skin. Makes skin look plumper and smoother almost immediately.

Karabat MU, Tuncer MC. Effects of hyaluronic acid on skin at the cellular level: a systematic review. Rev Assoc Med Bras. 2025;71(8):e20250208. — Systematic review of 45 studies found low-molecular-weight HA stimulates keratinocyte proliferation and migration while high-molecular-weight HA drives skin hydration, supporting topical HA as an effective skin-hydrating and barrier-supporting ingredient.

2025Meta-analysis (positive)PMID:40990743View source ↗

Bravo B et al., Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence, Dermatology and Therapy 2022;12(12):2657-2680 — HA-based cosmeceuticals reliably improve hydration and signs of skin aging

2022Meta-analysis (positive)PMID:36200921View source ↗

Lee SG et al., Hyaluronan Oligosaccharides Improve Rosacea-Like Phenotype through Anti-Inflammatory and Epidermal Barrier-Improving Effects, Annals of Dermatology 2020

2020Mechanism onlyPMID:33911737View source ↗
PanthenolModerate evidence5 citations

Pro-vitamin B5. Deeply hydrates and helps repair the skin barrier, calming dry or compromised skin.

Gao Y et al., Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment, Journal of Cosmetic Dermatology 2025;24(7):e70223 — double-blind RCT (n=60): panthenol mask decreased erythema, enhanced hydration, repaired barrier vs saline

2025Positive (efficacy)PMID:40613435View source ↗

Cho YS et al., Use of Dexpanthenol for Atopic Dermatitis-Benefits and Recommendations Based on Current Evidence, Journal of Clinical Medicine 2022;11(14):3943 — Korean-authored review; dexpanthenol improves barrier and reduces severity in mild-to-moderate AD

2022Meta-analysis (positive)PMID:35887707View source ↗

Heise R et al., Accelerated wound healing with a dexpanthenol-containing ointment after fractional ablative CO2 laser resurfacing of photo-damaged skin in a randomized prospective clinical trial, Cutaneous and Ocular Toxicology 2019;38(3):274-278 — RCT: dexpanthenol significantly faster wound closure vs petroleum jelly post-laser

2019Positive (efficacy)PMID:30897983View source ↗
AllantoinAnecdotal evidence6 citations

A gentle smoother and skin-soother. Reduces flakiness and helps the surface look more even.

Xu Z et al., Efficacy and Safety of Topical Compound Heparin Sodium Allantoin Gel for the Treatment of Rosacea, Journal of Cosmetic Dermatology 2025;24(4):e70129 — RCT (n=82, 12 weeks): allantoin gel improved erythema and alleviated itching/burning vs traditional therapy

2025Positive (efficacy)PMID:40177799View source ↗

Tan C et al., The combination of allantoin, bisabolol, D-panthenol and dipotassium glycyrrhizinate mitigates UVB-induced PGE2 synthesis by keratinocytes, International Journal of Cosmetic Science 2024;46(5):691-701 — in vitro: allantoin combination reduced UVB-induced PGE2, IL-1α, IL-6, IL-8, TNFα

2024Mechanism onlyPMID:38433250View source ↗

Saucedo-Acuna RA et al. (Mexico), Characterization and In Vivo Assay of Allantoin-Enriched Pectin Hydrogel for the Treatment of Skin Wounds, International Journal of Molecular Sciences 2023;24(8):7377 — allantoin-pectin hydrogel reduced wound healing time by ~71% with complete closure at day 15 in rat model

2023Mechanism onlyPMID:37108540View source ↗

Sources: 10 clinical journals and regulatory databases across the US, EU, Korea, Japan, and China. Every entry points to a specific document. See methodology for the full list and what each outcome label means.

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