Skip to main content
Shop Hada Labo Hada Labo Plus Sensitive Skin Hydrating Lotion
Moisturizer
Hada Labo

Hada Labo Plus Sensitive Skin Hydrating Lotion

~$19

What it's good for

Key actives from our research database. Click any to read the full evidence dossier.

  • GlycerinModerate evidenceFull dossier ↗

    A workhorse hydrator that pulls water into your skin. In nearly every good moisturizer for a reason.

    Good for: Hydrating

  • HeartleafModerate evidenceFull dossier ↗

    A calming K-beauty botanical that's also antibacterial, so it pairs well for acne-prone, sensitive skin.

    Good for: Anti-inflammatory, Anti-acne

  • Hyaluronic AcidStrong evidenceFull dossier ↗

    A pure hydrator that holds water in your skin. Makes skin look plumper and smoother almost immediately.

    Good for: Hydrating

  • Hydrolyzed CollagenModerate evidenceFull dossier ↗

    The protein your skin loses with age, broken down small enough to absorb. Multiple meta-analyses of RCTs show measurable wins in wrinkles, elasticity, and hydration after ~12 weeks. Most evidence is oral, but topical helps surface hydration too.

    Good for: Anti-aging, Hydrating

  • Panax GinsengStrong evidenceFull dossier ↗

    A staple in Hanbang (traditional Korean medicine) skincare. It's packed with antioxidants and ginsenosides that help firm the skin, boost circulation, and defend against environmental aging.

    Good for: Anti-aging, Antioxidant, Barrier repair

  • Tranexamic AcidStrong evidenceFull dossier ↗

    Fades stubborn dark patches like melasma and deep marks left behind by acne or hormonal shifts. The one to reach for when other brighteners haven't worked.

    Good for: Brightening

Evidence behind the ingredients

Real citations from our research database, one per tracked active in this product. Click any ingredient name to read its full evidence dossier.

GlycerinModerate evidence6 citations

A workhorse hydrator that pulls water into your skin. In nearly every good moisturizer for a reason.

Danby SG et al., Different types of emollient cream exhibit diverse physiological effects on the skin barrier in adults with atopic dermatitis, Clinical and Experimental Dermatology 2022;47(6):1154-1164 — glycerol+urea emollient delivered superior barrier-strengthening and irritant protection

2022Positive (efficacy)PMID:35167133View source ↗

Youssef R et al., Glycerol 85% efficacy on atopic skin and its microbiome: a randomized controlled trial, Journal of Dermatological Treatment 2021;32(7):730-736 — topical glycerol 85% RCT on atopic skin

2021Positive (efficacy)PMID:31869257View source ↗

Evans NJ et al., Human axillary skin condition is improved following incorporation of glycerol into the stratum corneum from an antiperspirant formulation, Archives of Dermatological Research 2017;309(9):739-748 — 4% glycerol penetrated axillary SC, reduced irritation, improved hydration

2017Positive (efficacy)PMID:28889318View source ↗
HeartleafModerate evidence8 citations

A calming K-beauty botanical that's also antibacterial, so it pairs well for acne-prone, sensitive skin.

Song Z et al., Inhibition of LPS-Induced Skin Inflammatory Response and Barrier Damage via MAPK/NF-kB Signaling Pathway by Houttuynia cordata Thunb Fermentation Broth, Foods 2024

2024Mechanism onlyPMID:38790770View source ↗

Kwon N et al., Protective Effects of Fermented Houttuynia cordata Against UVA and H2O2-Induced Oxidative Stress in Human Skin Keratinocytes, Applied Biochemistry and Biotechnology 2023;195(5):3027-3046 — Korean-authored; fermented H. cordata showed antioxidant and anti-inflammatory protection against UVA/H2O2 stress

2023Mechanism onlyPMID:36495375View source ↗

Rafiq S et al., Pharmacological Effects of Houttuynia cordata Thunb (H. cordata): A Comprehensive Review, Pharmaceuticals (Basel) 2022

2022Mechanism onlyPMID:36145299View source ↗
Hyaluronic AcidStrong evidence7 citations

A pure hydrator that holds water in your skin. Makes skin look plumper and smoother almost immediately.

Karabat MU, Tuncer MC. Effects of hyaluronic acid on skin at the cellular level: a systematic review. Rev Assoc Med Bras. 2025;71(8):e20250208. — Systematic review of 45 studies found low-molecular-weight HA stimulates keratinocyte proliferation and migration while high-molecular-weight HA drives skin hydration, supporting topical HA as an effective skin-hydrating and barrier-supporting ingredient.

2025Meta-analysis (positive)PMID:40990743View source ↗

Bravo B et al., Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence, Dermatology and Therapy 2022;12(12):2657-2680 — HA-based cosmeceuticals reliably improve hydration and signs of skin aging

2022Meta-analysis (positive)PMID:36200921View source ↗

Lee SG et al., Hyaluronan Oligosaccharides Improve Rosacea-Like Phenotype through Anti-Inflammatory and Epidermal Barrier-Improving Effects, Annals of Dermatology 2020

2020Mechanism onlyPMID:33911737View source ↗
+3 more ingredients
Hydrolyzed CollagenModerate evidence7 citations

The protein your skin loses with age, broken down small enough to absorb. Multiple meta-analyses of RCTs show measurable wins in wrinkles, elasticity, and hydration after ~12 weeks. Most evidence is oral, but topical helps surface hydration too.

Reilly DM, Kynaston L, Naseem S, Proudman E, Laceby D. A Clinical Trial Shows Improvement in Skin Collagen, Hydration, Elasticity, Wrinkles, Scalp, and Hair Condition following 12-Week Oral Intake of a Supplement Containing Hydrolysed Collagen. Dermatology Research and Practice. 2024. — Randomized double-blind placebo-controlled trial; 12-week oral collagen supplement showed 44.6% decrease in collagen fragmentation, +13.8% hydration, +22.7% elasticity, -19.6% wrinkle index vs placebo.

2024Positive (efficacy)PMID:39021368View source ↗

Demir-Dora D, Ozsoy U, Yildirim Y, et al. The Efficacy and Safety of CollaSel Pro® Hydrolyzed Collagen Peptide Supplementation without Addons in Improving Skin Health in Adult Females: A Double Blind, Randomized, Placebo-Controlled Clinical Study. Journal of Clinical Medicine. 2024 Sep 11. — Double-blind RCT (n=112); significant improvements in skin elasticity (p=0.009), hydration (p<0.001), and roughness vs placebo.

2024Positive (efficacy)PMID:39336856View source ↗

Pu SY et al., Effects of Oral Collagen for Skin Anti-Aging: A Systematic Review and Meta-Analysis, Nutrients 2023;15(9):2080 — 26 RCTs / 1,721 patients: hydrolyzed collagen significantly improved skin hydration and elasticity vs placebo across multiple collagen sources

2023Meta-analysis (positive)PMID:37432180View source ↗
Panax GinsengStrong evidence5 citations

A staple in Hanbang (traditional Korean medicine) skincare. It's packed with antioxidants and ginsenosides that help firm the skin, boost circulation, and defend against environmental aging.

Jung SW et al., Protective Effects of Korean Red Ginseng Against Oxidative Stress-Induced Damage in Human Hair, Annals of Dermatology 2025

2025Mechanism onlyPMID:39894668View source ↗

Kim H et al., The Beneficial Effect of Korean Red Ginseng Extract on Atopic Dermatitis Patients: An 8 Weeks Open, Noncomparative Clinical Study, Annals of Dermatology 2018

2018Positive (efficacy)PMID:29853744View source ↗

Park HM et al., A single-center, randomized, double-blind, placebo-controlled study on the efficacy and safety of enzyme-treated red ginseng powder complex (BG11001) for antiwrinkle and proelasticity in individuals with healthy skin, Journal of Ginseng Research 2016

2016Positive (efficacy)PMID:27616902View source ↗
Tranexamic AcidStrong evidence10 citations

Fades stubborn dark patches like melasma and deep marks left behind by acne or hormonal shifts. The one to reach for when other brighteners haven't worked.

Liang Y et al., Comparative efficacy and safety of tranexamic acid for melasma by different administration methods: A systematic review and network meta-analysis, Journal of Cosmetic Dermatology 2024 — oral TXA + topical agents most effective delivery route

2024Meta-analysis (positive)PMID:38059683View source ↗

Tranexamic Acid Ameliorates Skin Hyperpigmentation by Downregulating Endothelin-1 Expression in Dermal Microvascular Endothelial Cells, Annals of Dermatology 2024;36(3):151-162 — mechanism study showing oral TXA suppresses endothelin-1 in vascular endothelial cells

2024Mechanism onlyPMID:38816976View source ↗

Calacattawi R, Alshahrani M, Aleid M et al., Tranexamic acid as a therapeutic option for melasma management: a meta-analysis and systematic review of randomized controlled trials, Journal of Dermatological Treatment 2024;35(1):2361106 — pooled RCT evidence that tranexamic acid significantly reduces melasma severity via plasmin-inhibition of UV-triggered melanogenesis

2024Meta-analysis (positive)PMID:38843906View source ↗

Sources: 10 clinical journals and regulatory databases across the US, EU, Korea, Japan, and China. Every entry points to a specific document. See methodology for the full list and what each outcome label means.

Similar comparisons

← Back to shop

Not medical advice. GlowPal is educational. Patch-test new products and talk to a qualified healthcare professional before changing your routine, especially if you're pregnant, nursing, or have a diagnosed skin condition. See our terms.