Yam And Pumpkin Enzyme Peel
- AllantoinFair evidence
- CalendulaGood evidence
- ChamomileGood evidence
- Coenzyme Q10Good evidence
- GlycerinGood evidence
- Glycolic AcidExcellent evidence
- Routine step
- Treatment
- When
- Morning and evening
- Pairs well with
- Retinol, Mandelic Acid, Hyaluronic Acid, Ceramides
- Use with care
- 4 layering conflicts, listed below
Apply a thin layer to the areas you are treating, after serums and before moisturizer. Follow the label on frequency.
This product contains an active that can irritate at first. Patch test on the inner forearm for 24 hours and start two or three times a week.
Ingredient research in this formula
These are ingredient-level research links, not evidence that this exact product has been clinically tested.
A gentle smoother and skin-soother. Reduces flakiness and helps the surface look more even.
Good for: Anti-inflammatory, Hydrating
A botanical with real clinical wins for irritated, post-procedure, or recovering skin, with randomized-trial support behind its soothing reputation. Gentle enough for delicate, easily reactive skin and dry, sensitive patches.
Good for: Anti-inflammatory
The classic "tea-bag-on-puffy-eyes" botanical. Calms angry skin via well-studied anti-inflammatory pathways, gently. Good for reactive or rosacea-prone complexions.
Good for: Anti-inflammatory, Antioxidant
A naturally-occurring antioxidant your skin loses as you age. Topical CoQ10 restores some of what time depletes, supporting energy production in skin cells and softening wrinkle depth.
Good for: Antioxidant, Anti-aging
A workhorse hydrator that pulls water into your skin. In nearly every good moisturizer for a reason.
Good for: Hydrating
Exfoliates the surface of your skin to smooth rough texture and fade dullness. The strongest of the AHAs, so start slow.
Good for: Exfoliating
A gentler exfoliator that also hydrates as it works. Good entry point if you have sensitive skin and want to try acids.
Good for: Exfoliating, Hydrating
A workhorse antioxidant that defends your skin from daily oxidative damage. Pairs especially well with vitamin C, and it's in nearly every good moisturizer for a reason.
Good for: Antioxidant
The ultimate vegan alternative to snail mucin. It provides the same deeply hydrating, stretchy texture but is derived entirely from wild yam roots. Very soothing for sensitive skin.
Good for: Hydrating, Barrier repair
Evidence behind the ingredients
Real citations from our research database, one per tracked active in this product. Click any ingredient name to read its full evidence dossier.
A gentle smoother and skin-soother. Reduces flakiness and helps the surface look more even.
Xu Z et al., Efficacy and Safety of Topical Compound Heparin Sodium Allantoin Gel for the Treatment of Rosacea, Journal of Cosmetic Dermatology 2025;24(4):e70129: RCT (n=82, 12 weeks): allantoin gel improved erythema and alleviated itching/burning vs traditional therapy
Tan C et al., The combination of allantoin, bisabolol, D-panthenol and dipotassium glycyrrhizinate mitigates UVB-induced PGE2 synthesis by keratinocytes, International Journal of Cosmetic Science 2024;46(5):691-701: in vitro: allantoin combination reduced UVB-induced PGE2, IL-1α, IL-6, IL-8, TNFα
Saucedo-Acuna RA et al. (Mexico), Characterization and In Vivo Assay of Allantoin-Enriched Pectin Hydrogel for the Treatment of Skin Wounds, International Journal of Molecular Sciences 2023;24(8):7377: allantoin-pectin hydrogel reduced wound healing time by about 71% with complete closure at day 15 in rat model
A botanical with real clinical wins for irritated, post-procedure, or recovering skin, with randomized-trial support behind its soothing reputation. Gentle enough for delicate, easily reactive skin and dry, sensitive patches.
Deligiannidou GE et al. (Greece), An Update of Phytotherapeutic Advances of Marigold (Calendula officinalis L.) in Wound Healing, Plants (Basel) 2025: peer-reviewed review of 2020-2025 experimental and clinical evidence on Calendula formulations for skin regeneration: healing rate, cell proliferation, inflammatory modulation
Effect of oral Calendula officinalis on second-degree burn wound healing (Iran), Scars Burns and Healing 2023
Siddiquee S et al., Efficacy of topical Calendula officinalis on prevalence of radiation-induced dermatitis: A randomised controlled trial, Australasian Journal of Dermatology 2021;62(1):e35-e40: topical calendula reduced radiation-induced dermatitis
The classic "tea-bag-on-puffy-eyes" botanical. Calms angry skin via well-studied anti-inflammatory pathways, gently. Good for reactive or rosacea-prone complexions.
Essential Oil of Matricaria chamomilla Alleviates Psoriatic-Like Skin Inflammation by Inhibiting PI3K/Akt/mTOR and p38MAPK Signaling Pathway, Clinical Cosmetic and Investigational Dermatology 2024
Comparative analysis of whole plant, flower and root extracts of Chamomilla recutita L. (Germany), Frontiers in Immunology 2024
Xu J et al., Therapeutic effects of chamomile volatile oil nanoemulsion/Bletilla striata polysaccharides gels on atopic dermatitis, International Journal of Biological Macromolecules 2024: topical chamomile volatile oil nanoemulsion (19.07 nm) reduced skin damage, epidermal thickness, and mast cell infiltration in atopic dermatitis mice; rebalanced Th1/Th2
+−6 more ingredients
A naturally-occurring antioxidant your skin loses as you age. Topical CoQ10 restores some of what time depletes, supporting energy production in skin cells and softening wrinkle depth.
Li S et al., Ginsenoside Nanoliposomes Deliver Ergothioneine and Coenzyme Q10 to Address Skin Aging via Mitochondrial Mechanisms, Colloids and Surfaces B: Biointerfaces 2026
Lain ET, Agrawal N, Ruvolo E, Weise JM, Callender VD, The Role of Coenzyme Q10 in Skin Aging and Opportunities for Topical Intervention: A Review, Journal of Clinical and Aesthetic Dermatology 2024;17(8):42-47
Ayunin Q, Miatmoko A, Soeratri W, Erawati T, Susanto J, Legowo D, Improving the anti-ageing activity of coenzyme Q10 through protransfersome-loaded emulgel, Scientific Reports 2022;12(1):906: topical CoQ10 protransfersomal emulgel increased collagen density and fibroblast count in UV-aged mouse skin
A workhorse hydrator that pulls water into your skin. In nearly every good moisturizer for a reason.
Danby SG et al., Different types of emollient cream exhibit diverse physiological effects on the skin barrier in adults with atopic dermatitis, Clinical and Experimental Dermatology 2022;47(6):1154-1164: glycerol+urea emollient delivered superior barrier-strengthening and irritant protection
Youssef R et al., Glycerol 85% efficacy on atopic skin and its microbiome: a randomized controlled trial, Journal of Dermatological Treatment 2021;32(7):730-736: topical glycerol 85% RCT on atopic skin
Evans NJ et al., Human axillary skin condition is improved following incorporation of glycerol into the stratum corneum from an antiperspirant formulation, Archives of Dermatological Research 2017;309(9):739-748: 4% glycerol penetrated axillary SC, reduced irritation, improved hydration
Exfoliates the surface of your skin to smooth rough texture and fade dullness. The strongest of the AHAs, so start slow.
Liu H et al., Topical agents for acne (covers AHA / fruit-acid arm), Cochrane Database of Systematic Reviews 2020;5:CD011368: conclusion: clinical benefit is unclear
Sarkar R et al., Comparative Evaluation of Efficacy and Tolerability of Glycolic Acid, Salicylic-Mandelic Acid, and Phytic Acid Combination Peels in Melasma, Dermatologic Surgery 2016;42(3):384-391: 35% glycolic acid and salicylic-mandelic peels equally effective and safe for melasma in Indian skin
Kubiak M et al., Evaluation of 70% glycolic peels versus 15% trichloroacetic peels for the treatment of photodamaged facial skin in aging women, Dermatologic Surgery 2014;40(8):883-891: both peels improved photodamaged skin; glycolic acid showed faster hydration recovery
A gentler exfoliator that also hydrates as it works. Good entry point if you have sensitive skin and want to try acids.
Fanning N et al., Treatment of mild-to-moderate facial cutaneous aging using a combination peel containing 6% trichloroacetic acid and 12% lactic acid, Journal of Cosmetic Dermatology 2023;22(11):3033-3041: three monthly peels significantly improved clarity, pigmentation, fine lines, roughness in 32 subjects
Tang SC, Yang JH, Dual effects of alpha-hydroxy acids on the skin, Molecules 2018;23(4):863: effect concentration-dependent
Babilas P et al., Cosmetic and dermatologic use of alpha hydroxy acids, JDDG: Journal der Deutschen Dermatologischen Gesellschaft 2012: supports AHAs including lactic acid for photoaging, pigmentation, and barrier effects
A workhorse antioxidant that defends your skin from daily oxidative damage. Pairs especially well with vitamin C, and it's in nearly every good moisturizer for a reason.
Neves JR et al., Efficacy of a topical serum containing L-ascorbic acid, neohesperidin, pycnogenol, tocopherol, and hyaluronic acid in relation to skin aging signs, Journal of Cosmetic Dermatology 2022;21(10):4462-4469: tocopherol-containing antioxidant serum reduced pollution-induced damage and improved aging signs
Warshaw EM et al., Patch Testing With Tocopherol and Tocopherol Acetate: The North American Contact Dermatitis Group Experience, 2001 to 2016, Dermatitis 2021;32(5):308-318: 15-year NACDG data: positive patch-test reactions to tocopherol rare given widespread cosmetic use
Lin FH et al., Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin, Journal of Investigative Dermatology 2005;125(4):826-832: ferulic acid + vit C + vit E combo doubled photoprotection vs C+E alone (cross-listed; same paper cited for Ferulic Acid and Vit C)
The ultimate vegan alternative to snail mucin. It provides the same deeply hydrating, stretchy texture but is derived entirely from wild yam roots. Very soothing for sensitive skin.
Raj PS, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD, Rettie AE, Ross D, Slaga TJ, Snyder PW, Tilton S, Fiume M, Heldreth B, Dioscorea Villosa (Wild Yam) Root Extract, International Journal of Toxicology 2023: Cosmetic Ingredient Review Expert Panel reaffirmed Dioscorea Villosa (Wild Yam) Root Extract as safe in the present practices of use and concentration in cosmetics (safety only; no efficacy claim)
Sources: 10 clinical journals and regulatory databases across the US, EU, Korea, Japan, and China. Every entry points to a specific document. See methodology for the full list and what each outcome label means.
Layering conflicts
Ingredients in this product that can react with common actives. Avoid stacking unless noted.
- Retinolhigh
Retinol + glycolic acid is a classic barrier-buster. Use on different nights.
- Tretinoinhigh
Tretinoin + glycolic acid causes significant barrier disruption. Never layer.
- Adapalenemedium
Adapalene + glycolic acid can over-exfoliate. Alternate nights.
- Salicylic Acidmedium
AHA + BHA stacking risks over-exfoliation. Use a pre-formulated AHA/BHA product or alternate days.
Similar comparisons
Not medical advice. GlowPal is educational. Patch-test new products and talk to a qualified healthcare professional before changing your routine, especially if you're pregnant, nursing, or have a diagnosed skin condition. See our terms.