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Shop Axis-Y Made For Me By Me Biome Comforting Infused Toner
Toner
Axis-Y

Made For Me By Me Biome Comforting Infused Toner

~$17· AXIS-Y Biome Comforting Infused Toner

What it's good for

Key actives from our research database. Click any to read the full evidence dossier.

  • Centella AsiaticaModerate evidenceFull dossier ↗

    Also called "cica," it calms redness, repairs the skin barrier, and speeds up recovery. The go-to for irritated or reactive skin.

    Good for: Anti-inflammatory, Barrier repair

  • Citric AcidModerate evidenceFull dossier ↗

    A fruit-derived AHA that exfoliates and antioxidizes. It shares the same basic mechanism as glycolic and lactic acid but is weaker gram-for-gram; in practice you'll see it doing dual duty (a little exfoliation plus pH stabilisation) in multi-acid toners and serums. When it appears low on an ingredient list, it's adjusting pH; higher up, it's contributing real exfoliation.

    Good for: Exfoliating, Antioxidant

  • GlycerinModerate evidenceFull dossier ↗

    A workhorse hydrator that pulls water into your skin. In nearly every good moisturizer for a reason.

    Good for: Hydrating

  • Salicylic AcidStrong evidenceFull dossier ↗

    Goes into your pores and dissolves the oil and dead skin clogging them. Best for blackheads, whiteheads, and oily, acne-prone skin.

    Good for: Anti-acne, Exfoliating

  • Tea Tree OilModerate evidenceFull dossier ↗

    A natural acne spot-treatment that kills the bacteria behind red, painful pimples. Slower than benzoyl peroxide but with fewer side effects when used at 5%.

    Good for: Anti-acne, Anti-inflammatory

New to this? Patch test on your inner arm for 24 to 48 hours before applying to your face. If you have sensitive skin or rosacea, start 2 to 3 times per week and build up slowly.

Evidence behind the ingredients

Real citations from our research database, one per tracked active in this product. Click any ingredient name to read its full evidence dossier.

Centella AsiaticaModerate evidence6 citations

Also called "cica," it calms redness, repairs the skin barrier, and speeds up recovery. The go-to for irritated or reactive skin.

Hur N et al., A Randomized, Double-Blind, Placebo-Controlled Trial Assessing the Effects of Oral Centella asiatica Extract on Skin Aging-Related Parameters in Middle-Aged Korean Women, Nutrients 2026

2026Positive (efficacy)PMID:42196964View source ↗

Borowicz KK et al., Geroprotective Potential of Centella asiatica: Modulation of Cellular Aging, Nutrients 2026

2026Mechanism onlyPMID:42280293View source ↗

Witkowska K et al., Topical Application of Centella asiatica in Wound Healing: Recent Insights into Mechanisms and Clinical Efficacy, Pharmaceutics 2024;16(10):1252 — modern hydrogel and nanostructured Centella delivery systems accelerate wound healing across wound types

2024Meta-analysis (positive)PMID:39458583View source ↗
Citric AcidModerate evidence4 citations

A fruit-derived AHA that exfoliates and antioxidizes. It shares the same basic mechanism as glycolic and lactic acid but is weaker gram-for-gram; in practice you'll see it doing dual duty (a little exfoliation plus pH stabilisation) in multi-acid toners and serums. When it appears low on an ingredient list, it's adjusting pH; higher up, it's contributing real exfoliation.

Tang SC, Yang JH. Dual Effects of Alpha-Hydroxy Acids on the Skin. Molecules. 2018;23(4):863.

2018Mechanism onlyPMC:PMC6017965View source ↗

Yamamoto Y, Uede K, Yonei N, Kishioka A, Ohtani T, Furukawa F. Effects of alpha-hydroxy acids on the human skin of Japanese subjects: the rationale for chemical peeling. Journal of Dermatology. 2006 Jan;33(1):16-22. — Clinical-mechanistic study in Japanese subjects demonstrating AHA (including citric acid class) keratolytic and epidermal renewal effects as rationale for chemical peeling.

2006Mechanism onlyPMID:16469079View source ↗

Bernstein EF, Underhill CB, Lakkakorpi J, et al. Citric acid increases viable epidermal thickness and glycosaminoglycan content of sun-damaged skin. Dermatologic Surgery. 1997 Aug;23(8):689-694. — Mechanistic study showing topical citric acid increased viable epidermal thickness and dermal glycosaminoglycans in sun-damaged skin, similar to glycolic acid and retinoic acid.

1997Mechanism onlyPMID:9256916View source ↗
GlycerinModerate evidence6 citations

A workhorse hydrator that pulls water into your skin. In nearly every good moisturizer for a reason.

Danby SG et al., Different types of emollient cream exhibit diverse physiological effects on the skin barrier in adults with atopic dermatitis, Clinical and Experimental Dermatology 2022;47(6):1154-1164 — glycerol+urea emollient delivered superior barrier-strengthening and irritant protection

2022Positive (efficacy)PMID:35167133View source ↗

Youssef R et al., Glycerol 85% efficacy on atopic skin and its microbiome: a randomized controlled trial, Journal of Dermatological Treatment 2021;32(7):730-736 — topical glycerol 85% RCT on atopic skin

2021Positive (efficacy)PMID:31869257View source ↗

Evans NJ et al., Human axillary skin condition is improved following incorporation of glycerol into the stratum corneum from an antiperspirant formulation, Archives of Dermatological Research 2017;309(9):739-748 — 4% glycerol penetrated axillary SC, reduced irritation, improved hydration

2017Positive (efficacy)PMID:28889318View source ↗
+2 more ingredients
Salicylic AcidStrong evidence9 citations

Goes into your pores and dissolves the oil and dead skin clogging them. Best for blackheads, whiteheads, and oily, acne-prone skin.

Liu Y et al., Clinical Efficacy of a Salicylic Acid-Containing Gel on Acne Management and Skin Barrier Function: A 21-Day Prospective Study, Journal of Cosmetic Dermatology 2025;24(7):e70353 — salicylic acid gel reduced acne lesions, regulated sebum, improved hydration and barrier function

2025Positive (efficacy)PMID:40682377View source ↗

Ye R et al., 2% supramolecular salicylic acid hydrogel vs. adapalene gel in mild to moderate acne vulgaris: multicenter, randomized, evaluator-blind, parallel-controlled trial, Journal of Cosmetic Dermatology 2024;23(6):2125-2134 — 2% SSA hydrogel was equally effective as adapalene gel for mild-to-moderate acne

2024Positive (efficacy)PMID:38590107View source ↗

Brumley C et al. Allergic contact dermatitis to salicylic acid: A case series of relevant sensitization. Contact Dermatitis. 2024;91(2):133-138. doi:10.1111/cod.14573 — Case series of 489 patch-tested patients (2020-2024): 21 positive reactions to salicylic acid. Documents that ACD to SA is likely underreported; testing at 5% concentration feasible.

2024Safety assessmentPMID:38686774View source ↗
Tea Tree OilModerate evidence6 citations

A natural acne spot-treatment that kills the bacteria behind red, painful pimples. Slower than benzoyl peroxide but with fewer side effects when used at 5%.

Najafi-Taher R et al., A topical gel of tea tree oil nanoemulsion containing adapalene versus adapalene marketed gel in patients with acne vulgaris: a randomized clinical trial, Archives of Dermatological Research 2022;314(7):673-679 — RCT showed tea tree oil + adapalene nanoemulsion gel produced significantly better reduction in total, inflammatory and non-inflammatory acne lesions than standard adapalene

2022Positive (efficacy)PMID:34251536View source ↗

Zambello A et al. Tea tree oil contact sensitization in children. Contact Dermatitis. 2021;84(2):123-124. doi:10.1111/cod.13699 — Documents allergic contact dermatitis from tea tree oil exposure in pediatric patients identified through patch testing; highlights sensitization risk in children.

2021Safety assessmentPMID:32885466View source ↗

Malhi HK, Tu J, Riley TV, Kumarasinghe SP, Hammer KA, Tea tree oil gel for mild to moderate acne; a 12 week uncontrolled, open-label phase II pilot study, Australasian Journal of Dermatology 2017;58(3):205-210

2017Positive (efficacy)PMID:27000386View source ↗

Sources: 10 clinical journals and regulatory databases across the US, EU, Korea, Japan, and China. Every entry points to a specific document. See methodology for the full list and what each outcome label means.

Layering conflicts

Ingredients in this product that can react with common actives. Avoid stacking unless noted.

  • Retinol + salicylic acid can over-exfoliate and damage the barrier. Alternate nights.

  • Tretinoin + salicylic acid — major irritation risk. Strict separation required.

  • AHA + BHA stacking risks over-exfoliation. Use a pre-formulated AHA/BHA product or alternate days.

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Not medical advice. GlowPal is educational. Patch-test new products and talk to a qualified healthcare professional before changing your routine, especially if you're pregnant, nursing, or have a diagnosed skin condition. See our terms.