Triple Lipid Restore 2:4:2
What it's good for
Key actives from our research database. Click any to read the full evidence dossier.
Refills the natural barrier between your skin cells. Locks moisture in, keeps irritants out, calms dry or damaged skin.
Good for: Barrier repair
The third (and most often missing) lipid in the skin barrier triumvirate. Without it, even ceramide-heavy creams underperform. Topping it up is what lets compromised, aged, or eczema-prone skin actually rebuild its waterproof layer.
Good for: Barrier repair
Evidence behind the ingredients
Real citations from our research database, one per tracked active in this product. Click any ingredient name to read its full evidence dossier.
Refills the natural barrier between your skin cells. Locks moisture in, keeps irritants out, calms dry or damaged skin.
Andrew PV et al., Topical supplementation with physiological lipids rebalances the stratum corneum ceramide profile and strengthens skin barrier function in adults predisposed to atopic dermatitis, British Journal of Dermatology 2025;193(4):729-740 — physiological-lipid emulsion raised SC ceramide NP/AP and improved barrier function vs control
Nugroho WT, Sawitri, Astindari, Utomo B, Listiawan MY, Ervianti E, Astari L. The Efficacy of Moisturisers Containing Ceramide Compared with Other Moisturisers in the Management of Atopic Dermatitis: A Systematic Literature Review and Meta-Analysis. Indian J Dermatol. 2023;68(1):53-58. — Meta-analysis of 5 studies found ceramide-containing moisturisers produced significantly greater improvement in SCORAD compared with non-ceramide moisturisers in atopic dermatitis.
Shindo S et al., Effects of a moisturizer containing pseudo-ceramide and a eucalyptus extract on sweating function in adult atopic dermatitis: a double-blind, randomized, controlled left-right comparison clinical trial, Journal of Cosmetic Dermatology 2022;21(10):4503-4509 — pseudo-ceramide + eucalyptus moisturizer restored sweating function and barrier in AD adults
The third (and most often missing) lipid in the skin barrier triumvirate. Without it, even ceramide-heavy creams underperform. Topping it up is what lets compromised, aged, or eczema-prone skin actually rebuild its waterproof layer.
Sugarman JL, Parish LC. Efficacy of a lipid-based barrier repair formulation in moderate-to-severe pediatric atopic dermatitis. J Drugs Dermatol. 2009;8(12):1106-1111. — ceramide/cholesterol/fatty-acid triple-lipid formulation reduced disease severity, pruritus and improved sleep at days 14 and 28.
Chamlin SL, Kao J, Frieden IJ, Sheu MY, Fowler AJ, Fluhr JW, Williams ML, Elias PM. Ceramide-dominant barrier repair lipids alleviate childhood atopic dermatitis: changes in barrier function provide a sensitive indicator of disease activity. J Am Acad Dermatol. 2002;47(2):198-208. — physiologic ceramide:cholesterol:fatty-acid lipid mixture; SCORAD improved significantly in 22 of 24 patients.
Zettersten EM, Ghadially R, Feingold KR, Crumrine D, Elias PM. Optimal ratios of topical stratum corneum lipids improve barrier recovery in chronologically aged skin. J Am Acad Dermatol. 1997;37(3 Pt 1):403-408.
Sources: 10 clinical journals and regulatory databases across the US, EU, Korea, Japan, and China. Every entry points to a specific document. See methodology for the full list and what each outcome label means.
Full ingredient list
Everything on the package label, not just the tracked actives above.
- Contains fragrance: Linalool, LimoneneWorth knowing if you have sensitive or reactive skin.
- Contains silicones: Dimethicone, Peg-10 Dimethicone, Lauryl Peg-9 Polydimethylsiloxyethyl Dimethicone, Dimethicone/Peg-10/15 Crosspolymer, Peg/Ppg-18/18 DimethiconeNo irritancy evidence. CIR rates this safe as used; some shoppers avoid it by preference.
+−Show all 37 ingredients
Listed in the order printed on the package. By regulation, ingredients at 1% or higher are listed in descending order by concentration, so the first entry is the largest part of the formula.
- Aqua/Water/Eau
- Dimethicone
- Hydrogenated Polyisobutene
- Glycerin
- Cholesterol
- C12-15 Alkyl Benzoate
- Ceramide 3
- Helianthus Annuus Seed Oil Unsaponifiables/Sunflower Seed Oil Unsaponifiables
- Bis-Peg-18 Methyl Ether Dimethyl Silane
- Sodium Polyacrylate
- Peg-10 Dimethicone
- Nylon-12
- Lauryl Peg-9 Polydimethylsiloxyethyl Dimethicone
- Dimethicone/Peg-10/15 Crosspolymer
- Phenoxyethanol
- Disteardimonium Hectorite
- Hydroxyethylpiperazine Ethane Sulfonic Acid
- Ammonium Polyacryloyldimethyl Taurate
- Chlorphenesin
- Caprylyl Glycol
- Peg/Ppg-18/18 Dimethicone
- Propylene Carbonate
- Disodium Edta
- Acrylonitrile/Methyl Methacrylate/Vinylidene Chloride Copolymer
- Adenosine
- Dipropylene Glycol
- Lavandula Angustifolia Oil/Lavender Oil
- Rosmarinus Officinalis Leaf Oil/Rosemary Leaf Oil
- T-Butyl Alcohol
- Mentha Piperita Oil/Peppermint Oil
- Sodium Citrate
- Linalool
- Isobutane
- Ceramide Eop
- Bht
- Tocopherol
- Limonene
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