PDRN Rejuvenating Cream
What it's good for
Key actives from our research database. Click any to read the full evidence dossier.
Refills the natural barrier between your skin cells. Locks moisture in, keeps irritants out, calms dry or damaged skin.
Good for: Barrier repair
Evidence behind the ingredients
Real citations from our research database, one per tracked active in this product. Click any ingredient name to read its full evidence dossier.
Refills the natural barrier between your skin cells. Locks moisture in, keeps irritants out, calms dry or damaged skin.
Andrew PV et al., Topical supplementation with physiological lipids rebalances the stratum corneum ceramide profile and strengthens skin barrier function in adults predisposed to atopic dermatitis, British Journal of Dermatology 2025;193(4):729-740 — physiological-lipid emulsion raised SC ceramide NP/AP and improved barrier function vs control
Nugroho WT, Sawitri, Astindari, Utomo B, Listiawan MY, Ervianti E, Astari L. The Efficacy of Moisturisers Containing Ceramide Compared with Other Moisturisers in the Management of Atopic Dermatitis: A Systematic Literature Review and Meta-Analysis. Indian J Dermatol. 2023;68(1):53-58. — Meta-analysis of 5 studies found ceramide-containing moisturisers produced significantly greater improvement in SCORAD compared with non-ceramide moisturisers in atopic dermatitis.
Shindo S et al., Effects of a moisturizer containing pseudo-ceramide and a eucalyptus extract on sweating function in adult atopic dermatitis: a double-blind, randomized, controlled left-right comparison clinical trial, Journal of Cosmetic Dermatology 2022;21(10):4503-4509 — pseudo-ceramide + eucalyptus moisturizer restored sweating function and barrier in AD adults
Sources: 10 clinical journals and regulatory databases across the US, EU, Korea, Japan, and China. Every entry points to a specific document. See methodology for the full list and what each outcome label means.
Full ingredient list
Everything on the package label, not just the tracked actives above.
- Contains fragrance: FragranceWorth knowing if you have sensitive or reactive skin.
- Contains silicones: Phenyl Trimethicone, Dimethicone, Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone, Dimethicone/Vinyl Dimethicone CrosspolymerNo irritancy evidence. CIR rates this safe as used; some shoppers avoid it by preference.
+−Show all 46 ingredients
Listed in the order printed on the package. By regulation, ingredients at 1% or higher are listed in descending order by concentration, so the first entry is the largest part of the formula.
- Water
- Dipropylene Glycol
- Glycerin
- Phenyl Trimethicone
- Oenothera Biennis (Evening Primrose) Oil
- Cetearyl Alcohol
- Glyceryl Glucoside
- Niacinamide
- Beeswax
- Arginine
- PEG-100 Stearate
- Hydroxyacetophenone
- 1,2-Hexanediol
- Glyceryl Stearate
- Sodium Polyacrylate
- Carbomer
- Dimethicone
- Hydrogenated Polydecene
- Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone
- Sodium Dna
- Dimethicone/Vinyl Dimethicone Crosspolymer
- Fragrance
- Butylene Glycol
- Adenosine
- Trideceth-6
- Disodium EDTA
- Panthenol
- Sodium Hyaluronate
- Pentylene Glycol
- Hydrolyzed
- Sodium Dna
- Hyaluronic Acid
- Tripeptide-1
- Tocopherol
- Uracil
- Thymine
- Adenine
- Hydrogenated Lecithin
- Portulaca Oleracea Extract
- Acetyl Hexapeptide-8
- Cytosine
- Guanine
- Centella Asiatica Extract
- Chamomilla Recutita (Matricaria) Flower Extract
- Vitex Agnus Castus Extract
- Ceramide NP
Similar comparisons
Not medical advice. GlowPal is educational. Patch-test new products and talk to a qualified healthcare professional before changing your routine, especially if you're pregnant, nursing, or have a diagnosed skin condition. See our terms.