Double Up Cream Ectoin & Panthenol
What it's good for
Key actives from our research database. Click any to read the full evidence dossier.
Pro-vitamin B5. Deeply hydrates and helps repair the skin barrier, calming dry or compromised skin.
Good for: Hydrating, Barrier repair
A desert-bacteria-derived molecule that wraps skin cells in a protective water layer. Genuinely helpful for irritated, atopic-prone, or post-procedure skin.
Good for: Hydrating, Barrier repair, Anti-inflammatory
Evidence behind the ingredients
Real citations from our research database, one per tracked active in this product. Click any ingredient name to read its full evidence dossier.
Pro-vitamin B5. Deeply hydrates and helps repair the skin barrier, calming dry or compromised skin.
Gao Y et al., Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment, Journal of Cosmetic Dermatology 2025;24(7):e70223 — double-blind RCT (n=60): panthenol mask decreased erythema, enhanced hydration, repaired barrier vs saline
Cho YS et al., Use of Dexpanthenol for Atopic Dermatitis-Benefits and Recommendations Based on Current Evidence, Journal of Clinical Medicine 2022;11(14):3943 — Korean-authored review; dexpanthenol improves barrier and reduces severity in mild-to-moderate AD
Heise R et al., Accelerated wound healing with a dexpanthenol-containing ointment after fractional ablative CO2 laser resurfacing of photo-damaged skin in a randomized prospective clinical trial, Cutaneous and Ocular Toxicology 2019;38(3):274-278 — RCT: dexpanthenol significantly faster wound closure vs petroleum jelly post-laser
A desert-bacteria-derived molecule that wraps skin cells in a protective water layer. Genuinely helpful for irritated, atopic-prone, or post-procedure skin.
Wu PY et al., The Skin Hydration and Anti-Ageing Benefits of Ectoine, Achieved Through Enhanced Src-ERK-Mediated HAS-2 and JNK-Driven AQP-3 Expression in Human Keratinocytes, Along with the Inhibition of MMP-1-Induced Collagen-I Degradation in Human Fibroblasts, Both With and Without UVB Irradiation, International Journal of Cosmetic Science 2026
Abd Elazim NE, Awad SM, El-Naggar MS, Mohamed RH, Topical Ectoin Versus Topical Dexpanthenol for Managing Acute Radiodermatitis Associated With Breast Cancer Radiotherapy: A Randomized Double-Blind Study, Dermatitis 2023;34(6):516-524 — double-blind RCT showed ectoin reduced symptom severity (pain, itching) and quality-of-life impairment vs dexpanthenol
Hon KL, Kung JS, Ng WG, Leung TF, Testing an Ectoin Containing Emollient for Atopic Dermatitis, Current Pediatric Reviews 2019;15(3):191-194
Sources: 10 clinical journals and regulatory databases across the US, EU, Korea, Japan, and China. Every entry points to a specific document. See methodology for the full list and what each outcome label means.
Full ingredient list
Everything on the package label, not just the tracked actives above.
- Contains silicones: Vinyl DimethiconeNo irritancy evidence. CIR rates this safe as used; some shoppers avoid it by preference.
+−Show all 32 ingredients
Listed in the order printed on the package. By regulation, ingredients at 1% or higher are listed in descending order by concentration, so the first entry is the largest part of the formula.
- Water
- Squalane
- Butylene Glycol
- Glycerin
- Vinyl Dimethicone
- 1,2-Hexanediol
- Dipropylene Glycol
- Methylpropanediol
- Niacinamide
- Propanediol
- Betaine
- Ectoin
- Panthenol
- Sodium Hyaluronate
- Cetearyl Olivate
- Sorbitan Olivate
- Melia Azadirachta Flower Extract
- Melia Azadirachta Leaf Extract
- Coccinia Indica Fruit Extract
- Adenosine
- Ammonium Acryloyldimethyltaurate/VP Copolymer
- Acrylates/C10-30 Alkyl Acrylate Crosspolymer
- Disodium EDTA
- Solanum Melongena (Eggplant) Fruit Extract
- Ocimum Sanctum Leaf Extract
- Corallina Officinalis Extract
- Curcuma Longa (Turmeric) Root Extract
- Ethylhexylglycerin
- Polyquaternium-51
- Sodium Stearoyl Glutamate
- Tromethamine
- Aniba Rosodora (Rosewood) Wood Oil
Similar comparisons
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