Shop Anua Heartleaf Silky Moisture Mild Sunscreen SPF50+ Broad Spectrum 50ml
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Anua

Heartleaf Silky Moisture Mild Sunscreen SPF50+ Broad Spectrum 50ml

~$18· 50mlSPF 50
RednessDrynessRadiance

Evidence behind the ingredients

Real citations from our research database — one per tracked active in this product. Click any ingredient name to read its full evidence dossier.

Hyaluronic AcidStrong evidence7 citations

A pure hydrator that holds water in your skin. Makes skin look plumper and smoother almost immediately.

Bravo B et al., Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence, Dermatology and Therapy 2022;12(12):2657-2680 — HA-based cosmeceuticals reliably improve hydration and signs of skin aging

2022Meta-analysis — positivePMID:36200921View source ↗

Lee SG et al., Hyaluronan Oligosaccharides Improve Rosacea-Like Phenotype through Anti-Inflammatory and Epidermal Barrier-Improving Effects, Annals of Dermatology 2020

2020Mechanism onlyPMID:33911737View source ↗

An JH et al., Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin, Annals of Dermatology 2019;31(3):263-271 — cross-linked HA microneedle patches improved wrinkles on Korean skin with minimal discomfort

2019Positive — efficacyPMID:33911590View source ↗
HeartleafModerate evidence9 citations

A calming K-beauty botanical that's also antibacterial, so it pairs well for acne-prone, sensitive skin.

Huang R et al., Houttuynia cordata polysaccharides ameliorate atopic dermatitis in mice through modulation of skin immune barrier and lipid metabolism, International Journal of Biological Macromolecules 2025;314:144264 — South-Central Minzu U Wuhan; HCP restored lipid metabolic homeostasis and modulated inflammation in AD mice

2025Mechanism onlyPMID:40393586View source ↗

Song Z et al., Inhibition of LPS-Induced Skin Inflammatory Response and Barrier Damage via MAPK/NF-kB Signaling Pathway by Houttuynia cordata Thunb Fermentation Broth, Foods 2024

2024Mechanism onlyPMID:38790770View source ↗

Kwon N et al., Protective Effects of Fermented Houttuynia cordata Against UVA and H2O2-Induced Oxidative Stress in Human Skin Keratinocytes, Applied Biochemistry and Biotechnology 2023;195(5):3027-3046 — Korean-authored; fermented H. cordata showed antioxidant and anti-inflammatory protection against UVA/H2O2 stress

2023Mechanism onlyPMID:36495375View source ↗
PanthenolModerate evidence5 citations

Pro-vitamin B5. Deeply hydrates and helps repair the skin barrier, calming dry or compromised skin.

Gao Y et al., Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment, Journal of Cosmetic Dermatology 2025;24(7):e70223 — double-blind RCT (n=60): panthenol mask decreased erythema, enhanced hydration, repaired barrier vs saline

2025Positive — efficacyPMID:40613435View source ↗

Cho YS et al., Use of Dexpanthenol for Atopic Dermatitis-Benefits and Recommendations Based on Current Evidence, Journal of Clinical Medicine 2022;11(14):3943 — Korean-authored review; dexpanthenol improves barrier and reduces severity in mild-to-moderate AD

2022Meta-analysis — positivePMID:35887707View source ↗

Heise R et al., Accelerated wound healing with a dexpanthenol-containing ointment after fractional ablative CO2 laser resurfacing of photo-damaged skin in a randomized prospective clinical trial, Cutaneous and Ocular Toxicology 2019;38(3):274-278 — RCT: dexpanthenol significantly faster wound closure vs petroleum jelly post-laser

2019Positive — efficacyPMID:30897983View source ↗
+3 more ingredients
Vitamin EModerate evidence6 citations

A workhorse antioxidant that defends your skin from daily oxidative damage. Pairs especially well with vitamin C, and it's in nearly every good moisturizer for a reason.

Neves JR et al., Efficacy of a topical serum containing L-ascorbic acid, neohesperidin, pycnogenol, tocopherol, and hyaluronic acid in relation to skin aging signs, Journal of Cosmetic Dermatology 2022;21(10):4462-4469 — tocopherol-containing antioxidant serum reduced pollution-induced damage and improved aging signs

2022Positive — efficacyPMID:35150043View source ↗

Warshaw EM et al., Patch Testing With Tocopherol and Tocopherol Acetate: The North American Contact Dermatitis Group Experience, 2001 to 2016, Dermatitis 2021;32(5):308-318 — 15-year NACDG data: positive patch-test reactions to tocopherol rare given widespread cosmetic use

2021Safety assessmentPMID:34238818View source ↗

Lin FH et al., Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin, Journal of Investigative Dermatology 2005;125(4):826-832 — ferulic acid + vit C + vit E combo doubled photoprotection vs C+E alone (cross-listed; same paper cited for Ferulic Acid and Vit C)

2005Positive — efficacyPMID:16185284View source ↗
UreaStrong evidence4 citations

A small molecule your skin already makes. Low concentrations deeply hydrate dry skin; higher concentrations soften thick, scaly patches. A workhorse for eczema and ichthyosis.

Jawed I et al., Effect of topical treatment with urea in ichthyosis, atopic dermatitis, psoriasis, and other skin conditions: a systematic review, Annals of Medicine and Surgery 2025

2025Meta-analysis — positivePMID:40109645View source ↗

Piquero-Casals J, Morgado-Carrasco D, Granger C, Trullas C, Jesus-Silva A, Krutmann J, Urea in Dermatology: A Review of its Emollient, Moisturizing, Keratolytic, Skin Barrier Enhancing and Antimicrobial Properties, Dermatology and Therapy (Heidelberg) 2021;11(6):1905-1915

2021Positive — efficacyPMID:34596890View source ↗

Ademola J, Frazier C, Kim SJ, Theaux C, Saudez X, Clinical evaluation of 40% urea and 12% ammonium lactate in the treatment of xerosis, American Journal of Clinical Dermatology 2002;3(3):217-22 — randomized double-blind comparison; 40% urea cream achieved improvement faster than 12% ammonium lactate lotion across hydration, texture, and roughness

2002Positive — efficacyPMID:11978141View source ↗
1 more citation view all on the Urea page ↗
GlycerinModerate evidence4 citations

A workhorse hydrator that pulls water into your skin. In nearly every good moisturizer for a reason.

Danby SG et al., Different types of emollient cream exhibit diverse physiological effects on the skin barrier in adults with atopic dermatitis, Clinical and Experimental Dermatology 2022;47(6):1154-1164 — glycerol+urea emollient delivered superior barrier-strengthening and irritant protection

2022Positive — efficacyPMID:35167133View source ↗

Evans NJ et al., Human axillary skin condition is improved following incorporation of glycerol into the stratum corneum from an antiperspirant formulation, Archives of Dermatological Research 2017;309(9):739-748 — 4% glycerol penetrated axillary SC, reduced irritation, improved hydration

2017Positive — efficacyPMID:28889318View source ↗

Fluhr JW et al., Glycerol and the skin: holistic approach to its origin and functions, British Journal of Dermatology 2008;159(1):23-34 — improves xerosis and barrier function

2008Positive — efficacyPMID:18510666View source ↗

Sources: PubMed · KCI · J-Stage · CNKI · Wanfang · SFD · MFDS · Cochrane · SCCS · CIR. Every entry points to a specific document. See methodology for what each outcome label means.

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