Bisabolol for Seborrheic dermatitis

The "calm-down" molecule in many sensitive-skin formulas. Reduces redness and stinging without bleaching your barrier, and plays nicely on top of retinoids or exfoliating acids.

Why it works for Seborrheic dermatitis

Calms the redness and inflammation in facial patches. It comes from chamomile and turns down the skin's inflammation signals. It is used in facial creams that pair it with an antifungal (piroctone olamine), and those creams have beaten plain cream in trials for mild to moderate facial seborrheic dermatitis.

How Bisabolol works

Chamomile-derived sesquiterpene alcohol that suppresses TNF-α and IL-6 in keratinocytes and macrophages and dampens TPA-induced skin inflammation in dose-dependent fashion.

Evidence

4 citations from our ingredient database. Full citation list on the Bisabolol ingredient page.

journal2025

Wu Y et al., Exploring the mechanism of alpha-Bisabolol in the treatment of psoriasis based on network pharmacology and experimental validation, European Journal of Pharmacology 2025 — alpha-bisabolol suppressed inflammation in TNF-alpha-treated keratinocytes and psoriasis mice via PI3K/AKT and NF-kB pathways; reduced IL-6, IL-1beta, TNF-alpha and skin lesions

journal2024

Karami H et al. (Brazil), Development of a hydrogel containing bisabolol-loaded nanocapsules for the treatment of atopic dermatitis in a Balb/c mice model, International Journal of Pharmaceutics 2024

journal2024

Tan C et al. (Brazil), The combination of allantoin, bisabolol, D-panthenol and dipotassium glycyrrhizinate mitigates UVB-induced PGE2 synthesis by keratinocytes, International Journal of Cosmetic Science 2024

journal2017

Werner R et al. (Germany), Determination of the Influence of the Antiphlogistic Ingredients Panthenol and Bisabolol on the SPF Value in vivo, Skin Pharmacology and Physiology 2017;30(4) — in vivo SPF + erythema study confirmed bisabolol does not suppress erythema response (no false-positive SPF inflation) while remaining a recognized antiphlogistic active

Products with Bisabolol in our catalog

These are the catalog products that list Bisabolol as a tracked ingredient.

PDRN Essence Stick Balm

$16 · Serum

I'm from

Rice Cream

$18.99 · Moisturizer

Glow Recipe

Avocado Ceramide Recovery Serum

$37.5 · Serum

Origins

Drink Up Intensive Overnight Hydrating Face Mask with Niacinamide & Hyaluronic Acid 2.5 fl oz

$27.3 · Treatment

Andalou

1000 Roses® Heavenly Night Cream

$23 · Moisturizer

Burt's Bees

Aloe After Sun Soother

$9 · Moisturizer

Full Bisabolol guide →Seborrheic dermatitis overview →