Moderate evidence

Bisabolol for Rosacea

The "calm-down" molecule in many sensitive-skin formulas. Reduces redness and stinging without bleaching your barrier, and plays nicely on top of retinoids or exfoliating acids.

Why it works for Rosacea

Calms skin inflammation. It is a compound from chamomile that quiets the inflammatory signals in skin. It turns up often in sensitive-skin and rosacea products because it soothes without much risk of triggering an allergy.

How Bisabolol works

Chamomile-derived sesquiterpene alcohol that suppresses TNF-α and IL-6 in keratinocytes and macrophages and dampens TPA-induced skin inflammation in dose-dependent fashion.

Evidence

4 citations from our ingredient database. Full citation list on the Bisabolol ingredient page.

journal2025

Wu Y et al., Exploring the mechanism of alpha-Bisabolol in the treatment of psoriasis based on network pharmacology and experimental validation, European Journal of Pharmacology 2025 — alpha-bisabolol suppressed inflammation in TNF-alpha-treated keratinocytes and psoriasis mice via PI3K/AKT and NF-kB pathways; reduced IL-6, IL-1beta, TNF-alpha and skin lesions

journal2024

Karami H et al. (Brazil), Development of a hydrogel containing bisabolol-loaded nanocapsules for the treatment of atopic dermatitis in a Balb/c mice model, International Journal of Pharmaceutics 2024

journal2024

Tan C et al. (Brazil), The combination of allantoin, bisabolol, D-panthenol and dipotassium glycyrrhizinate mitigates UVB-induced PGE2 synthesis by keratinocytes, International Journal of Cosmetic Science 2024

journal2017

Werner R et al. (Germany), Determination of the Influence of the Antiphlogistic Ingredients Panthenol and Bisabolol on the SPF Value in vivo, Skin Pharmacology and Physiology 2017;30(4) — in vivo SPF + erythema study confirmed bisabolol does not suppress erythema response (no false-positive SPF inflation) while remaining a recognized antiphlogistic active

Products with Bisabolol in our catalog

These are the catalog products that list Bisabolol as a tracked ingredient.

PDRN Essence Stick Balm

$16 · Serum

I'm from

Rice Cream

$18.99 · Moisturizer

Glow Recipe

Avocado Ceramide Recovery Serum

$37.5 · Serum

Origins

Drink Up Intensive Overnight Hydrating Face Mask with Niacinamide & Hyaluronic Acid 2.5 fl oz

$27.3 · Treatment

Andalou

1000 Roses® Heavenly Night Cream

$23 · Moisturizer

Burt's Bees

Aloe After Sun Soother

$9 · Moisturizer

Full Bisabolol guide →Rosacea overview →