Skip to main content
Shop SK-II R.N.A. Power Eye Cream
Treatment
SK-II

R.N.A. Power Eye Cream

~$145· 15g
Fine lines & firmnessDryness

What it's good for

Key actives from our research database. Click any to read the full evidence dossier.

  • PiteraModerate evidenceFull dossier ↗

    SK-II's signature ingredient, a specific yeast filtrate that improves clarity and texture over time.

    Good for: Brightening, Hydrating

  • Matrixyl PeptidesModerate evidenceFull dossier ↗

    Signals your skin to make more collagen. Quiet but real support for firmness and fine lines with consistent daily use.

    Good for: Anti-aging

Evidence behind the ingredients

Real citations from our research database, one per tracked active in this product. Click any ingredient name to read its full evidence dossier.

PiteraModerate evidence4 citations

SK-II's signature ingredient, a specific yeast filtrate that improves clarity and texture over time.

Miyamoto K et al., Significant Reversal of Facial Wrinkle, Pigmented Spot and Roughness by Daily Application of Galactomyces Ferment Filtrate-Containing Skin Products for 12 Months—An 11-Year Longitudinal Skin Aging Rejuvenation Study, Journal of Clinical Medicine 2023;12(3):1168 — Pitera is SK-II's commercial name for GFF; this 11-year longitudinal study directly evaluates the same active

2023Positive (efficacy)PMID:36769815View source ↗

Nakajima H et al., Transcriptomic Analysis of Human Keratinocytes Treated with Galactomyces Ferment Filtrate, a Beneficial Cosmetic Ingredient, Journal of Clinical Medicine 2022;11(16):4645 — GFF activates AhR/NRF2 antioxidant pathways while suppressing inflammatory transcripts

2022Mechanism onlyPMID:36012891View source ↗

Anwar AI et al., The effectiveness of Galactomyces ferment filtrate, dexpanthenol, and Centella asiatica combination serum in the treatment of post-acne hyperpigmentation in subjects with skin of color, Skinmed 2021;19(2):110-115 — Pitera is SK-II's commercial name for Galactomyces ferment filtrate; trial covers the same active

2021Positive (efficacy)PMID:33938432View source ↗
Matrixyl PeptidesModerate evidence6 citations

Signals your skin to make more collagen. Quiet but real support for firmness and fine lines with consistent daily use.

Yang Y et al., Comprehensive evaluation of the efficacy and safety of a new multi-component anti-aging topical eye cream, Skin Research and Technology 2024;30(7):e13790 — 12-week study of active complex containing Matrixyl 3000 peptides showed significant improvement in hydration, elasticity, periorbital wrinkles

2024Positive (efficacy)PMID:38932444View source ↗

Aruan RR et al., Double-blind, Randomized Trial on the Effectiveness of Acetylhexapeptide-3 Cream and Palmitoyl Pentapeptide-4 Cream for Crow's Feet, Journal of Clinical and Aesthetic Dermatology 2023;16(2):37-43 — RCT of topical palmitoyl pentapeptide-4 (Matrixyl) for periorbital wrinkles

2023Positive (efficacy)PMID:36909866View source ↗

Imhof L, Leuthard D, Topical Over-the-Counter Antiaging Agents: An Update and Systematic Review, Dermatology 2021;237(2):217-229 — SR covering topical antiaging peptides

2021Meta-analysis (positive)PMID:32882685View source ↗

Sources: 10 clinical journals and regulatory databases across the US, EU, Korea, Japan, and China. Every entry points to a specific document. See methodology for the full list and what each outcome label means.

Full ingredient list

Everything on the package label, not just the tracked actives above.

Drying alcohol freeSulfates free
  • Contains fragrance: Benzyl Alcohol, FragranceWorth knowing if you have sensitive or reactive skin.
  • Contains parabens: Methylparaben, Propylparaben, EthylparabenNo irritancy evidence. CIR rates this safe as used; some shoppers avoid it by preference.
  • Contains silicones: Dimethicone, Vinyl Dimethicone/​Methicone Silsesquioxane Crosspolymer, Dimethiconol, MethiconeNo irritancy evidence. CIR rates this safe as used; some shoppers avoid it by preference.
+Show all 52 ingredients

Listed in the order printed on the package. By regulation, ingredients at 1% or higher are listed in descending order by concentration, so the first entry is the largest part of the formula.

  1. Water
  2. Glycerin
  3. Galactomyces Ferment Filtrate
  4. Niacinamide
  5. Isohexadecane
  6. Butylene Glycol
  7. Pentylene Glycol
  8. Isopropyl Isostearate
  9. Petrolatum
  10. Dimethicone
  11. Caprylic/​Capric Triglyceride
  12. Vinyl Dimethicone/​Methicone Silsesquioxane Crosspolymer
  13. Polyacrylamide
  14. Phytosteryl/​Behenyl/​Octyldodecyl Lauroyl Glutamate
  15. Stearyl Alcohol
  16. Cetyl Alcohol
  17. C13-14 Isoparaffin
  18. Behenyl Alcohol
  19. Tocopheryl Acetate
  20. Polymethylsilsesquioxane
  21. Panthenol
  22. Nylon-12
  23. Benzyl Alcohol
  24. Dimethiconol
  25. Methylparaben
  26. PEG-100 Stearate
  27. Laureth-7
  28. Cetearyl Glucoside
  29. Cetearyl Alcohol
  30. Stearic Acid
  31. Mica
  32. Disodium EDTA
  33. Propylparaben
  34. Sodium PEG-7 Olive Oil Carboxylate
  35. Ethylparaben
  36. PEG-7 Glyceryl Cocoate
  37. Chlorella Vulgaris Extract
  38. Sodium Hydroxide
  39. Hydrolyzed Lupine Protein
  40. Fragrance
  41. Medicago Sativa (Alfalfa) Extract
  42. Hydrolyzed Soy Protein
  43. Polyquaternium-7
  44. Palmitoyl Dipeptide-7
  45. Hydrolyzed Yeast Protein
  46. Acanthopanax Senticosus (Eleuthero) Root Extract
  47. Palmitoyl Pentapeptide-4
  48. Methylsilanol Tri-PEG-8 Glyceryl Cocoate
  49. Methicone
  50. Cynara Scolymus (Artichoke) Leaf Extract
  51. Ci 77891
  52. Ci 77492

Similar comparisons

← Back to shop

Not medical advice. GlowPal is educational. Patch-test new products and talk to a qualified healthcare professional before changing your routine, especially if you're pregnant, nursing, or have a diagnosed skin condition. See our terms.