Rapid Clear Stubborn Acne Spot Treatment Gel 10% Benzoyl Peroxide (1 oz)
Tracked ingredients
Key actives from our research database. Click any to read the full evidence dossier.
Evidence behind the ingredients
Real citations from our research database — one per tracked active in this product. Click any ingredient name to read its full evidence dossier.
Kills the bacteria that cause inflammatory acne. The first thing to reach for when you have red, painful pimples.
Huang CY et al., Comparative Efficacy of Pharmacological Treatments for Acne Vulgaris: A Network Meta-Analysis of 221 Randomized Controlled Trials, Annals of Family Medicine 2023;21(4):358-369 — BPO combinations among most effective topical regimens for acne
Stein Gold L et al., Efficacy and Safety of a Fixed-Dose Clindamycin Phosphate 1.2%, Benzoyl Peroxide 3.1%, and Adapalene 0.15% Gel for Moderate-to-Severe Acne: A Randomized Phase II Study of the First Triple-Combination Drug, American Journal of Clinical Dermatology 2022;23(1):93-104 — triple-combination gel superior to vehicle and dyad comparators
Yang Z et al., Topical benzoyl peroxide for acne, Cochrane Database of Systematic Reviews 2020;3:CD011154 — BPO modestly more effective than placebo, low-certainty evidence
Sources: PubMed · KCI · J-Stage · CNKI · Wanfang · SFD · MFDS · Cochrane · SCCS · CIR. Every entry points to a specific document. See methodology for what each outcome label means.
Layering conflicts
Ingredients in this product that can react with common actives. Avoid stacking unless noted.
- Vitamin Cmedium
Benzoyl peroxide breaks down vitamin C, making both less effective. Use one in the morning and the other at night.
- Retinolmedium
Benzoyl peroxide can break down retinol. Use one in the morning and the other at night, or pick a stabilized formula made to combine them.
- Tretinoinmedium
Benzoyl peroxide breaks down tretinoin unless they're in a stabilized formula made to combine them. Use one in the morning and the other at night.
Similar comparisons
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