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Shop Mediheal PDRN Lifting Pad
Treatment
Mediheal

PDRN Lifting Pad

~$26.4· 100 pads
Fine lines & firmnessRadiance

What it's good for

Key actives from our research database. Click any to read the full evidence dossier.

  • PolydeoxyribonucleotideAnecdotal evidenceFull dossier ↗

    The "salmon DNA" trending in K-beauty and Korean clinics. Strong wound-healing pedigree translated into anti-aging. Speeds repair after lasers/microneedling, smooths fine lines, and brightens. Often layered with vitamin C and niacinamide. Worth knowing: salmon- or trout-derived PDRN has much stronger clinical evidence than plant ("phyto") PDRN, and the dose matters more than the marketing. Favor products that list a real PDRN concentration (roughly 1,000+ ppm) over big headline numbers on plant-derived versions.

    Good for: Barrier repair, Anti-aging

Evidence behind the ingredients

Real citations from our research database, one per tracked active in this product. Click any ingredient name to read its full evidence dossier.

PolydeoxyribonucleotideAnecdotal evidence4 citations

The "salmon DNA" trending in K-beauty and Korean clinics. Strong wound-healing pedigree translated into anti-aging. Speeds repair after lasers/microneedling, smooths fine lines, and brightens. Often layered with vitamin C and niacinamide. Worth knowing: salmon- or trout-derived PDRN has much stronger clinical evidence than plant ("phyto") PDRN, and the dose matters more than the marketing. Favor products that list a real PDRN concentration (roughly 1,000+ ppm) over big headline numbers on plant-derived versions.

Lee D et al., Skin Regeneration and Barrier-Improvement Efficacy of Polydeoxyribonucleotide Isolated from Panax Ginseng Adventitious Root, Molecules 2023;28(21):7240 — plant-derived PDRN promoted keratinocyte/fibroblast proliferation and strengthened barrier function

2023Mechanism onlyPMID:37959659View source ↗

Lee S, Won KH et al., A Mixture of Topical Forms of Polydeoxyribonucleotide, Vitamin C, and Niacinamide Attenuated Skin Pigmentation and Increased Skin Elasticity by Modulating Nrf2, Molecules 2022;27(4):1276 — topical PDRN + Vit C + niacinamide reduced melanin and improved elasticity in UV-B model, comparable to hydroquinone

2022Positive (efficacy)PMID:35209068View source ↗

Squadrito F et al., Polydeoxyribonucleotide: A Promising Biological Platform to Accelerate Impaired Skin Wound Healing, Pharmaceuticals (Basel) 2021;14(11):1103 — review documenting PDRN activation of adenosine A2A receptors, VEGF release, and accelerated wound healing across diabetic, thermal, and ischemic models

2021Mechanism onlyPMID:34832885View source ↗

Sources: 10 clinical journals and regulatory databases across the US, EU, Korea, Japan, and China. Every entry points to a specific document. See methodology for the full list and what each outcome label means.

Full ingredient list

Everything on the package label, not just the tracked actives above.

Fragrance freeDrying alcohol freeSulfates freeParabens freeSilicones free
+Show all 44 ingredients

Listed in the order printed on the package. By regulation, ingredients at 1% or higher are listed in descending order by concentration, so the first entry is the largest part of the formula.

  1. Water
  2. Glycerin
  3. Glycereth-26
  4. Niacinamide
  5. Methylpropanediol
  6. Rosa Damascena Flower Water
  7. 1,2-Hexanediol
  8. Betaine
  9. Hydroxyacetophenone
  10. Hydroxyethyl Urea
  11. Dipotassium Glycyrrhizate
  12. Sodium Citrate
  13. Octyldodeceth-16
  14. Panthenol
  15. PVP
  16. Citric Acid
  17. Adenosine
  18. Disodium EDTA
  19. Butylene Glycol
  20. Allantoin
  21. Methyl Diisopropyl Propionamide
  22. Gardenia Florida Flower Extract
  23. Ribes Nigrum (Black Currant) Leaf Extract
  24. Rubus Suavissimus (Raspberry) Leaf Extract
  25. Sea Water
  26. Hedera Helix (Ivy) Leaf/​Stem Extract
  27. Houttuynia Cordata Extract
  28. Chrysanthemum Zawadskii Extract
  29. Pelargonium Graveolens Flower Oil
  30. Glycine Soja (Soybean) Seed Extract
  31. Myosotis Sylvatica Flower/​Leaf/​Stem Extract
  32. Polyglyceryl-10 Laurate
  33. Glutathione
  34. Hydrogenated Lecithin
  35. Ectoin
  36. Gluconolactone
  37. Ethyl Hexanediol
  38. Rosa Damascena Flower Extract
  39. Quercetin
  40. Squalane
  41. Sodium Dna (100 Ppb)
  42. Caprylyl Glycol
  43. Hydrolyzed Proanthocyanidin
  44. Acetyl Hexapeptide-8

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