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Shop Mary&May Tranexamic Acid + Glutathione Eye Cream Mini
Treatment
Mary&May

Tranexamic Acid + Glutathione Eye Cream Mini

· Standard Size
At a glance
Routine step
Treatment
When
Morning and evening
Pairs well with
Niacinamide, Vitamin C, Azelaic Acid, Hydroquinone
How to use

Apply a thin layer to the areas you are treating, after serums and before moisturizer. Follow the label on frequency.

Ingredient research in this formula

These are ingredient-level research links, not evidence that this exact product has been clinically tested.

  • Tranexamic AcidExcellent evidenceFull dossier

    Fades stubborn dark patches like melasma and deep marks left behind by acne or hormonal shifts. The one to reach for when other brighteners haven't worked.

    Good for: Brightening

  • GlutathioneGood evidenceFull dossier

    A "master antioxidant" your body already makes. In skincare it gently lightens overall tone and helps fade pigmentation when used consistently over months.

    Good for: Brightening, Antioxidant

Evidence behind the ingredients

Real citations from our research database, one per tracked active in this product. Click any ingredient name to read its full evidence dossier.

Tranexamic AcidExcellent evidence10 citations

Fades stubborn dark patches like melasma and deep marks left behind by acne or hormonal shifts. The one to reach for when other brighteners haven't worked.

Liang Y et al., Comparative efficacy and safety of tranexamic acid for melasma by different administration methods: A systematic review and network meta-analysis, Journal of Cosmetic Dermatology 2024: oral TXA + topical agents most effective delivery route

2024Meta-analysis (positive)PMID:38059683View source ↗

Tranexamic Acid Ameliorates Skin Hyperpigmentation by Downregulating Endothelin-1 Expression in Dermal Microvascular Endothelial Cells, Annals of Dermatology 2024;36(3):151-162: mechanism study showing oral TXA suppresses endothelin-1 in vascular endothelial cells

2024Mechanism onlyPMID:38816976View source ↗

Calacattawi R, Alshahrani M, Aleid M et al., Tranexamic acid as a therapeutic option for melasma management: a meta-analysis and systematic review of randomized controlled trials, Journal of Dermatological Treatment 2024;35(1):2361106: pooled RCT evidence that tranexamic acid significantly reduces melasma severity via plasmin-inhibition of UV-triggered melanogenesis

2024Meta-analysis (positive)PMID:38843906View source ↗
GlutathioneGood evidence5 citations

A "master antioxidant" your body already makes. In skincare it gently lightens overall tone and helps fade pigmentation when used consistently over months.

Stanescu C et al., Glutathione in Skin Aging and Tissue Regeneration: A Systematic Review of Molecular Mechanisms, Redox Modulation, and Biomedical Implications, Molecules 2026

2026Meta-analysis (positive)PMID:41900080View source ↗

Sarkar R et al., Glutathione as a skin-lightening agent and in melasma: a systematic review, International Journal of Dermatology 2025

2025Meta-analysis (mixed)PMID:39444151View source ↗

Wahab S et al., Combination of topical and oral glutathione as a skin-whitening agent: a double-blind randomized controlled clinical trial, International Journal of Dermatology 2021;60(8):1013-1018: 8-week RCT showed combination significantly lowered melanin and raised lightness vs placebo

2021Positive (efficacy)PMID:33871071View source ↗

Sources: 10 clinical journals and regulatory databases across the US, EU, Korea, Japan, and China. Every entry points to a specific document. See methodology for the full list and what each outcome label means.

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