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Shop Mary&May Tranexamic Acid + Glutathione Eye Cream
Treatment
Mary&May

Tranexamic Acid + Glutathione Eye Cream

~$11.85· Standard Size

What it's good for

Key actives from our research database. Click any to read the full evidence dossier.

  • Tranexamic AcidStrong evidenceFull dossier ↗

    Fades stubborn dark patches like melasma and deep marks left behind by acne or hormonal shifts. The one to reach for when other brighteners haven't worked.

    Good for: Brightening

  • GlutathioneModerate evidenceFull dossier ↗

    A "master antioxidant" your body already makes. In skincare it gently lightens overall tone and helps fade pigmentation when used consistently over months.

    Good for: Brightening, Antioxidant

Evidence behind the ingredients

Real citations from our research database, one per tracked active in this product. Click any ingredient name to read its full evidence dossier.

Tranexamic AcidStrong evidence10 citations

Fades stubborn dark patches like melasma and deep marks left behind by acne or hormonal shifts. The one to reach for when other brighteners haven't worked.

Liang Y et al., Comparative efficacy and safety of tranexamic acid for melasma by different administration methods: A systematic review and network meta-analysis, Journal of Cosmetic Dermatology 2024 — oral TXA + topical agents most effective delivery route

2024Meta-analysis (positive)PMID:38059683View source ↗

Tranexamic Acid Ameliorates Skin Hyperpigmentation by Downregulating Endothelin-1 Expression in Dermal Microvascular Endothelial Cells, Annals of Dermatology 2024;36(3):151-162 — mechanism study showing oral TXA suppresses endothelin-1 in vascular endothelial cells

2024Mechanism onlyPMID:38816976View source ↗

Calacattawi R, Alshahrani M, Aleid M et al., Tranexamic acid as a therapeutic option for melasma management: a meta-analysis and systematic review of randomized controlled trials, Journal of Dermatological Treatment 2024;35(1):2361106 — pooled RCT evidence that tranexamic acid significantly reduces melasma severity via plasmin-inhibition of UV-triggered melanogenesis

2024Meta-analysis (positive)PMID:38843906View source ↗
GlutathioneModerate evidence5 citations

A "master antioxidant" your body already makes. In skincare it gently lightens overall tone and helps fade pigmentation when used consistently over months.

Stanescu C et al., Glutathione in Skin Aging and Tissue Regeneration: A Systematic Review of Molecular Mechanisms, Redox Modulation, and Biomedical Implications, Molecules 2026

2026Meta-analysis (positive)PMID:41900080View source ↗

Sarkar R et al., Glutathione as a skin-lightening agent and in melasma: a systematic review, International Journal of Dermatology 2025

2025Meta-analysis (mixed)PMID:39444151View source ↗

Wahab S et al., Combination of topical and oral glutathione as a skin-whitening agent: a double-blind randomized controlled clinical trial, International Journal of Dermatology 2021;60(8):1013-1018 — 8-week RCT showed combination significantly lowered melanin and raised lightness vs placebo

2021Positive (efficacy)PMID:33871071View source ↗

Sources: 10 clinical journals and regulatory databases across the US, EU, Korea, Japan, and China. Every entry points to a specific document. See methodology for the full list and what each outcome label means.

Full ingredient list

Everything on the package label, not just the tracked actives above.

Drying alcohol freeSulfates freeParabens free
  • Contains fragrance: FragranceWorth knowing if you have sensitive or reactive skin.
  • Contains silicones: Dimethiconol, Dimethicone/​Vinyl Dimethicone CrosspolymerNo irritancy evidence. CIR rates this safe as used; some shoppers avoid it by preference.
+Show all 38 ingredients

Listed in the order printed on the package. By regulation, ingredients at 1% or higher are listed in descending order by concentration, so the first entry is the largest part of the formula.

  1. Purified Water
  2. Ethylhexyl Palmitate
  3. Glycereth-26
  4. Glycerin
  5. Cetearyl Alcohol
  6. Niacinamide
  7. Hydrogenated Poly(C6-14 Olefin)
  8. Beeswax
  9. Caprylic/​Capric Triglyceride
  10. Polyglyceryl-2 Stearate
  11. Dipropylene Glycol
  12. Isododecane
  13. Glyceryl Stearate
  14. Hydroxyethyl Acrylate/​Sodium Acryloyldimethyl Taurate Copolymer
  15. Stearyl Alcohol
  16. Glycol Stearate Se
  17. Sodium Polyacrylate
  18. Hydroxyacetophenone
  19. Stearic Acid
  20. Dimethiconol
  21. Dimethicone/​Vinyl Dimethicone Crosspolymer
  22. Hydrogenated Polydecene
  23. Hydrogenated Lecithin
  24. Tranexamic Acid (1,000Ppm)
  25. Betaine
  26. Glutathione (1,000Ppm)
  27. Panthenol
  28. Fragrance
  29. Hippophae Rhamnoides Fruit Oil
  30. Butylene Glycol
  31. Adenosine
  32. Sorbitan Isostearate
  33. Caprylyl Glycol
  34. Trideceth-6
  35. 1,2-Hexanediol
  36. Disodium EDTA
  37. Sodium Hyaluronate
  38. Ascorbic Acid

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Not medical advice. GlowPal is educational. Patch-test new products and talk to a qualified healthcare professional before changing your routine, especially if you're pregnant, nursing, or have a diagnosed skin condition. See our terms.