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Shop Hada Labo Kouji Treatment Cream
Treatment
Hada Labo

Kouji Treatment Cream

~$25· 1.76 Ounce (Pack of 1)

What it's good for

Key actives from our research database. Click any to read the full evidence dossier.

  • GlycerinModerate evidenceFull dossier ↗

    A workhorse hydrator that pulls water into your skin. In nearly every good moisturizer for a reason.

    Good for: Hydrating

  • Rice Ferment FiltrateAnecdotal evidenceFull dossier ↗

    The rice-water glow trend behind viral rice toners and essences. Lab and animal studies point to brightening and hydration, but human studies are still thin. Think of it as a pleasant, low-risk hydrator with promising early evidence rather than a proven brightener.

    Good for: Brightening, Hydrating

  • Shea ButterModerate evidenceFull dossier ↗

    A rich, naturally occlusive plant butter from the African karite tree. Soothes dry, irritation-prone skin, refills the lipid barrier, and was well tolerated enough in randomized trials that most participants used it comfortably as a daily emollient.

    Good for: Barrier repair, Hydrating, Anti-inflammatory

Evidence behind the ingredients

Real citations from our research database, one per tracked active in this product. Click any ingredient name to read its full evidence dossier.

GlycerinModerate evidence6 citations

A workhorse hydrator that pulls water into your skin. In nearly every good moisturizer for a reason.

Danby SG et al., Different types of emollient cream exhibit diverse physiological effects on the skin barrier in adults with atopic dermatitis, Clinical and Experimental Dermatology 2022;47(6):1154-1164 — glycerol+urea emollient delivered superior barrier-strengthening and irritant protection

2022Positive (efficacy)PMID:35167133View source ↗

Youssef R et al., Glycerol 85% efficacy on atopic skin and its microbiome: a randomized controlled trial, Journal of Dermatological Treatment 2021;32(7):730-736 — topical glycerol 85% RCT on atopic skin

2021Positive (efficacy)PMID:31869257View source ↗

Evans NJ et al., Human axillary skin condition is improved following incorporation of glycerol into the stratum corneum from an antiperspirant formulation, Archives of Dermatological Research 2017;309(9):739-748 — 4% glycerol penetrated axillary SC, reduced irritation, improved hydration

2017Positive (efficacy)PMID:28889318View source ↗
Rice Ferment FiltrateAnecdotal evidence3 citations

The rice-water glow trend behind viral rice toners and essences. Lab and animal studies point to brightening and hydration, but human studies are still thin. Think of it as a pleasant, low-risk hydrator with promising early evidence rather than a proven brightener.

Yan X, Yang M, Cai X, et al., Fermented rice bran extract delays skin aging by increasing the synthesis of collagen and elastin, Front Pharmacol 2025;16:1692491 — across cell, 3D-tissue and mouse models fermented rice bran extract increased collagen and elastin, reduced TEWL and improved elasticity

2025Mechanism onlyDOI:10.3389/fphar.2025.1692491View source ↗

Yang F et al., In Vitro Anti-Aging Effects of Yeast/Rice Fermentation Filtrate Combined with Sialic Acid in Cosmetic Applications, Antioxidants (Basel) 2025

2025Mechanism onlyPMID:41154493View source ↗

Sangkaew O, Yompakdee C, Fermented Unpolished Black Rice (Oryza sativa L.) Inhibits Melanogenesis via ERK, p38, and AKT Phosphorylation in B16F10 Melanoma Cells, J Microbiol Biotechnol 2020;30(8):1184-1194 — fermented black rice reduced melanin and tyrosinase activity in vitro (anti-melanogenesis mechanism)

2020Mechanism onlyPMID:32423183View source ↗
Shea ButterModerate evidence4 citations

A rich, naturally occlusive plant butter from the African karite tree. Soothes dry, irritation-prone skin, refills the lipid barrier, and was well tolerated enough in randomized trials that most participants used it comfortably as a daily emollient.

O'Connor RJ et al., Clinical Evaluation of a Diaper Containing a Shea Butter-Based Emollient and Impact on Diapered Skin Erythema, Pediatr Dermatol 2025;42(3):532-538 — RCT n=271 infants, shea-butter diaper reduced dermatitis

2025Positive (efficacy)PMID:40189822View source ↗

Burnett CL, Bergfeld WF, Belsito DV, et al. Safety Assessment of Butyrospermum parkii (Shea)-Derived Ingredients as Used in Cosmetics. Cosmetic Ingredient Review Expert Panel Final Report.

2024Safety assessmentDOI:10.1177/10915818231224230View source ↗

Verallo-Rowell VM, Katalbas SS, Pangasinan JP. Natural (Mineral, Vegetable, Coconut, Essential) Oils and Contact Dermatitis. Curr Allergy Asthma Rep. 2016;16(7):51. — discussing shea butter unsaponifiable fraction NF-kB inhibition and dermatologic use.

2016Mechanism onlyPMID:27373890View source ↗

Sources: 10 clinical journals and regulatory databases across the US, EU, Korea, Japan, and China. Every entry points to a specific document. See methodology for the full list and what each outcome label means.

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