Ingredients Exfoliating Silica Spicules
109Sp
Tier · Anecdotal evidence
Exfoliating · Anti-aging

Silica Spicules

INCI: Hydrolyzed Sponge · Also called: Sponge Spicules, Micro-needles, Spicule Tok

Liquid microneedling in a bottle. It causes a temporary prickly sensation but creates tiny pathways in your skin so all your other expensive serums can actually penetrate deeper.

For your skin

Liquid microneedling in a bottle. It causes a temporary prickly sensation but creates tiny pathways in your skin so all your other expensive serums can actually penetrate deeper.

Want the science? Keep reading ↓

Mechanism of action

Microscopic needle-like structures harvested from marine sponges that embed in the stratum corneum for up to 72 hours, creating microchannels that dramatically boost the absorption of subsequent actives while stimulating microcirculation.

Why we tier this anecdotal

4 cited papers across 2 countries. Most of what's cited here is mechanism-level or in-vitro work. We track this as Anecdotal until controlled clinical trials accumulate.

3
China
1
International

Cited research

🇨🇳

He W, Zhang C, Lai H, Wu G, Xiong M, Peng H, Chen M, Wang KJ, The topical application of Sphistin(12-38) in combination with sponge spicules for the acne treatment, Drug Delivery and Translational Research 2025 — sponge spicules increased skin penetration of an antimicrobial peptide ~6-fold; combination cured 100% of rabbit-ear acne in vivo over 2 weeks (animal/penetration mechanism)

2025Mechanism onlyPMID:39107673View source ↗
🇨🇳

Jin Y, Zhang C, Jia M, Chen M, Enhanced Dermal Delivery of Nanoparticulate Formulation of Cutibacterium acnes Using Sponge Spicules for Atopic Dermatitis Treatment, International Journal of Nanomedicine 2025 — Haliclona sp. sponge spicules enhanced dermal delivery of a nanoparticulate formulation (delivery mechanism, preclinical)

2025Mechanism onlyPMID:40103747View source ↗
🇨🇳

Zhang C, Duan J, Huang Y, Chen M, Enhanced Skin Delivery of Therapeutic Peptides Using Spicule-Based Topical Delivery Systems, Pharmaceutics 2021;13(12):2119 — marine sponge (Haliclona sp.) spicules created microchannels in the stratum corneum that enhanced transdermal delivery of peptides; permeability scaled with spicule aspect ratio (delivery mechanism, in-vitro/ex-vivo)

2021Mechanism onlyPMID:34959402View source ↗
🌐

Udompataikul M, Wongniraspai M, Showpittapornchai U, Jariyapongsakul A, The study on effects and safety of Spongilla lacustris in 3% hydrogen peroxide solution on rat skin, Journal of the Medical Association of Thailand 2012 — rat-skin study: Spongilla spicules punctured the epidermis and enhanced hydrogen-peroxide penetration; safe short-term, long-term granuloma risk noted (penetration mechanism, animal)

2012Mechanism onlyPMID:23513460View source ↗

Sources: PubMed · KCI · J-Stage · CNKI · Wanfang · SFD · MFDS · Cochrane · SCCS · CIR. Every entry points to a specific document. See methodology for what each outcome label means.