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Ingredients Hydrating Jojoba Oil
81Jo
Tier · Moderate evidence
Hydrating · Barrier repair · Anti-inflammatory

Jojoba Oil

INCI: Simmondsia Chinensis (Jojoba) Seed Oil · Also called: Jojoba

Technically a wax that masquerades as oil, molecularly closer to your own sebum than any other plant oil. Hydrates without clogging pores, calms inflammation, and plays well in acne-prone and sensitive routines.

For your skin

Technically a wax that masquerades as oil, molecularly closer to your own sebum than any other plant oil. Hydrates without clogging pores, calms inflammation, and plays well in acne-prone and sensitive routines.

Want the science? Keep reading ↓

Mechanism of action

Liquid wax ester (not a triglyceride) whose chain length and polarity mimic human sebum; integrates into intercellular lipids, restores stratum corneum integrity, and shows non-comedogenic emollience even on oily/acne-prone skin.

Why we tier this moderate

6 cited papers across 3 countries. The mechanism is well-described and there's at least one controlled trial in the literature, but we tier this Moderate rather than Strong to stay honest about how many specific papers we cite directly.

3
European Union
2
International
1
United States

Cited research

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Tietel Z, Melamed S, Ogen-Shtern N, et al. Topical application of jojoba (Simmondsia chinensis L.) wax enhances the synthesis of pro-collagen III and hyaluronic acid and reduces inflammation in the ex-vivo human skin organ culture model. Frontiers in Pharmacology. 2024;15:1333085. — Ex-vivo human skin model showing jojoba wax reduced LPS-induced IL-6/IL-8/TNFα by ~30% and enhanced pro-collagen III and hyaluronic acid synthesis.

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Blaak J, Staib P, An updated review on efficacy and benefits of sweet almond, evening primrose and jojoba oils in skin care applications, International Journal of Cosmetic Science 2022;44(1):1-9 — jojoba oil documented as effective for strengthening stratum corneum integrity, recovery, and lipid ratio

2022Meta-analysis (positive)PMID:34957578View source ↗
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Lin TK, Zhong L, Santiago JL, Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils, International Journal of Molecular Sciences 2017;19(1):70 — jojoba reviewed among 19 plant oils: supports stratum-corneum lipid replenishment, anti-inflammatory and wound-healing effects

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Pazyar N, Yaghoobi R, Ghassemi MR, Kazerouni A, Rafeie E, Jamshydian N. Jojoba in dermatology: a succinct review. Giornale Italiano di Dermatologia e Venereologia. 2013 Dec;148(6):687-691. — Narrative dermatology review covering jojoba's skin barrier, moisturizing, anti-inflammatory, and non-comedogenic properties.

2013Positive (efficacy)PMID:24442052View source ↗
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Ranzato E, Martinotti S, Burlando B. Wound healing properties of jojoba liquid wax: an in vitro study. Journal of Ethnopharmacology. 2011 Mar 24;134(2):443-449. — In vitro study showing jojoba liquid wax accelerated wound closure of HaCaT keratinocytes and human dermal fibroblasts.

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Meyer J et al., Evaluation of additive effects of hydrolyzed jojoba (Simmondsia chinensis) esters and glycerol: a preliminary study, J Cosmet Dermatol 2008;7(4):268-74 — DB RCT, hydrolyzed jojoba improved skin condition/TEWL

2008Positive (efficacy)PMID:19146603View source ↗

Sources: 10 clinical journals and regulatory databases across the US, EU, Korea, Japan, and China. Every entry points to a specific document. See methodology for the full list and what each outcome label means.