For your skin
A "molecule your own immune cells make," now bottled. Kills surface bacteria without nuking the barrier, calms itch and redness in eczema, and gives compromised or post-procedure skin a clean reset, gentle enough to spray around eyes.
Want the science? Keep reading ↓Mechanism of action
Endogenous oxidant produced by neutrophil myeloperoxidase; at cosmetic concentrations (~0.01-0.05%) it is broadly antimicrobial yet non-cytotoxic, inhibits NF-κB-driven inflammatory genes (Ptgs2, Il19, Tlr4), and blunts itch signaling in atopic models.
Why we tier this moderate
2 cited papers across 1 country. The mechanism is well-described and there's at least one controlled trial in the literature, but we tier this Moderate rather than Strong to stay honest about how many specific papers we cite directly.
Cited research
Wentworth AB et al., Topical hypochlorous acid (HOCl) blocks inflammatory gene expression and tumorigenic progression in UV-exposed SKH-1 high risk mouse skin, Redox Biology 2021;46:102108 — topical HOCl suppressed UV-induced inflammatory genes (Ptgs2, Il19, Tlr4) and tumor burden in photocarcinogenesis model
Fukuyama T et al., Hypochlorous acid is antipruritic and anti-inflammatory in a mouse model of atopic dermatitis, Clinical and Experimental Allergy 2018;48(1):78-88 — 0.05% HOCl hydrogel significantly reduced scratching, inflammatory cytokines, and itch behavior in AD model, comparably to topical steroid
Sources: PubMed · KCI · J-Stage · CNKI · Wanfang · SFD · MFDS · Cochrane · SCCS · CIR. Every entry points to a specific document. See methodology for what each outcome label means.