Ingredients Antioxidant Astaxanthin
41At
Sourced from microbe
Tier · Moderate evidence
Antioxidant

Astaxanthin

INCI: Astaxanthin · Also called: Haematococcus Pluvialis Extract

A powerful pink antioxidant from algae. Defends against UV and environmental damage.

For your skin

A powerful pink antioxidant from algae. Defends against UV and environmental damage.

Want the science? Keep reading ↓

Mechanism of action

Carotenoid antioxidant from algae that quenches singlet oxygen far more efficiently than vitamin E.

Why we tier this moderate

8 cited papers across 3 countries. The mechanism is well-described and there's at least one controlled trial in the literature, but we tier this Moderate rather than Strong to stay honest about how many specific papers we cite directly.

5
Japan
2
Korea
1
International

Cited research

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Chung BY et al., Astaxanthin Protects Ultraviolet B-Induced Oxidative Stress and Apoptosis in Human Keratinocytes via Intrinsic Apoptotic Pathway, Annals of Dermatology 2022;34(2):125-131 — astaxanthin significantly inhibited UVB-induced cytotoxicity and ROS in human keratinocytes

2022Mechanism onlyPMID:35450317View source ↗
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Zhou X et al., Systematic Review and Meta-Analysis on the Effects of Astaxanthin on Human Skin Ageing, Nutrients 2021;13(9):2917 — meta-analysis: oral astaxanthin improves skin moisture and elasticity; wrinkle data inconclusive

2021Meta-analysis — mixedPMID:34578794View source ↗
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Ito N et al., The Protective Role of Astaxanthin for UV-Induced Skin Deterioration in Healthy People — A Randomized, Double-Blind, Placebo-Controlled Trial, Nutrients 2018;10(7):817 — 4 mg/day oral astaxanthin protected against UV-induced skin deterioration

2018Positive — efficacyPMID:29941810View source ↗
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Tominaga K et al., Protective effects of astaxanthin on skin deterioration, Journal of Clinical Biochemistry and Nutrition 2017;61(1):33-39 — 16-week RCT (n=65 women): 6-12 mg/day astaxanthin maintained skin moisture and prevented age-related wrinkle worsening vs placebo

2017Positive — efficacyPMID:28751807View source ↗
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Tsukahara H et al., Effects of Intake of Astaxanthin Contained Drink on Skin Condition, Japanese Journal of Complementary and Alternative Medicine 2016;13(2):57-62 — 8-week double-blind placebo-controlled RCT (n=20 Japanese women 30-49): 3 mg/day astaxanthin significantly improved moisture, TEWL, elasticity, minimal erythema dose, and skin texture vs placebo

2016Positive — efficacyJSTAGE:jcam-13-2-57View source ↗
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Yoon HS et al., Supplementing with dietary astaxanthin combined with collagen hydrolysate improves facial elasticity and decreases matrix metalloproteinase-1 and -12 expression: a comparative study with placebo, Journal of Medicinal Food 2014;17(7):810-816 — combination supplement improved facial elasticity and reduced MMP-1/-12

2014Positive — efficacyPMID:24955642View source ↗
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Tominaga K et al., Cosmetic benefits of astaxanthin on human subjects, Acta Biochimica Polonica 2012;59(1):43-7 — 6 mg/day oral + topical reduced crow's-feet wrinkles, age spots; improved elasticity & moisture

2012Positive — efficacyPMID:22428137View source ↗
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Suganuma K et al., Astaxanthin attenuates the UVA-induced up-regulation of matrix-metalloproteinase-1 and skin fibroblast elastase in human dermal fibroblasts, Journal of Dermatological Science 2010;58(2):136-142 — in-vitro: 4-8 μM astaxanthin after UVA significantly attenuated MMP-1 and SFE/NEP induction in human dermal fibroblasts

2010Mechanism onlyPMID:20219323View source ↗

Sources: PubMed · KCI · J-Stage · CNKI · Wanfang · SFD · MFDS · Cochrane · SCCS · CIR. Every entry points to a specific document. See methodology for what each outcome label means.